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Place of alfacalcidol in treatment of osteoporosis and osteoporotic fractures

Published:25 December 2022 DOI: 10.33667/2078-5631-2022-29-8-12
N. Toroptsova,?O. Nikitinskaya,?O. Dobrovolskaya

Abstract

Alfacalcidol has shown its efficacy and safety in the treatment of patients with osteoporosis (OP) during various clinical studies. The article presents data from a study conducted in real clinical practice in order to assess the relevance of alfacalcidol in the treatment of OP patients and the patients' adherence to treatment. A survey of doctors and patients with OP and low-energy fractures was conducted. Alfacalcidol was prescribed by doctors in 27 % of cases, while in 19 % – in combination with antiresorptive drugs. Among the interviewed patients with the average duration of OP 3 years, 25 % of the respondents took alfacalcidol. Adherence to treatment during the last year was 38 %. Follow-up of patients after a low-energy fracture showed that 31 % of them received alfacalcidol, among whom treatment adherence for 36 months was 50 % for monotherapy, and 21 % for combination therapy. Thus, the survey showed that in real clinical practice, alfacalcidol is widely used both in the management of patients with OP and after low-energy fractures.

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Related products
Procduct Name CAS Molecular Formula Supplier Price
Alfacalcidol 41294-56-8 C27H44O2 446 suppliers $37.00-$2913.80
Alfacalcidol 1809782-28-2 C42H71O5PSi3 9 suppliers Inquiry
Alfacalcidol 147125-21-1 C39H70O4Si2 5 suppliers Inquiry
Alfacalcidol 189102-76-9 C25H52O2Si2 3 suppliers Inquiry
Alfacalcidol 197647-61-3 C13H24O 2 suppliers Inquiry
Alfacalcidol 146434-16-4 C18H32O3 2 suppliers Inquiry
Alfacalcidol 157306-59-7 C21H40O2Si 1 suppliers Inquiry
Alfacalcidol 1279049-53-4 C27H44O2 - Inquiry

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