一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

ChemicalBook >> journal list >> Analytical Chemistry >>article
Analytical Chemistry

Analytical Chemistry

IF: 6.7
Download PDF

Distinguishment of Glycan Isomers by Trapped Ion Mobility Spectrometry

Published:24 June 2021 DOI: 10.1021/acs.analchem.1c01461 PMID: 34165974
Zhan Gao, Lei Li, Weiwei Chen, Zihan Ma, Yuan Li, Yuanji Gao, Chuan-Fan Ding, Xiaoyong Zhao*, Yuanjiang Pan*

Abstract

The in-depth study of glycan has drawn large research interests since it is one of the main biopolymers on the earth with a variety of biological functions. However, the distinguishment of glycans is still difficult due to the similarity of the monosaccharide building block, the anomer, and the linkage of glycosidic bonds. In this study, four novel and representative copper-bound diastereoisomeric complex ions were simultaneously detected in a single measurement by trapped ion mobility mass spectrometry, including mononuclear copper-bound dimeric ions [(Cu2+)(A)(l-Ser)-H]+ and [(Cu2+)(A)(l-His)-H]+, the mononuclear copper-bound trimeric ion [(Cu2+)(A)(l-Ser)(l-His)-H]+, and the binuclear copper-bound tetrameric ion [(Cu2+)2(A)(l-Ser)2(l-His)-3H]+ (where A denotes an oligosaccharide, and l-Ser and l-His denote l-serine and l-histidine, respectively). By combining the collision cross sections of complex ions, 23 oligosaccharide isomers were successfully distinguished including two pairs of sialylated glycan linkage isomers. In addition, due to the unique dissociation pathways of the trimeric ion, both the relative and absolute quantification of the individual isomer in the mixture could be determined using a mass spectrometry-based kinetic method. Finally, the method established above was successfully applied to the identification and quantification of glycan isomers in dairy beverages and juice. The method in the present study was sensitive to the fine difference of glycan isomers and might have wide applicability in glycoscience.

Substances (18)

Materials
Procduct Name CAS Molecular Formula Supplier Price
D-(+)-Cellobiose 528-50-7 C12H22O11 521 suppliers $8.00-$2190.00
D-(+)-Cellobiose 528-50-7 C12H22O11 521 suppliers $8.00-$2190.00
D-(+)-Cellobiose 528-50-7 C12H22O11 521 suppliers $8.00-$2190.00
D-(+)-Cellobiose 528-50-7 C12H22O11 521 suppliers $8.00-$2190.00
Maltose 69-79-4 C12H22O11 486 suppliers $5.00-$3029.39
Maltose 69-79-4 C12H22O11 486 suppliers $5.00-$3029.39
Maltose 69-79-4 C12H22O11 486 suppliers $5.00-$3029.39
Maltose 69-79-4 C12H22O11 486 suppliers $5.00-$3029.39
ISOMALTOSE 499-40-1 C12H22O11 389 suppliers $16.00-$3282.70
ISOMALTOSE 499-40-1 C12H22O11 389 suppliers $16.00-$3282.70

Similar articles

IF:8.3

Efficient Separation of Xylene Isomers by a Pillar-Layer Metal–Organic Framework

ACS Applied Materials & Interfaces Liping Yang, Hanbang Liu,etc Published: 30 August 2021
高碑店市| 清苑县| 海淀区| 罗山县| 博乐市| 山东省| 舒兰市| 达州市| 房山区| 乌苏市| 广州市| 河北省| 崇阳县| 巩留县| 揭西县| 枣阳市| 京山县| 南岸区| 吕梁市| 若尔盖县| 尼勒克县| 竹山县| 肃宁县| 微博| 陕西省| 金华市| 河南省| 会同县| 商都县| 宾阳县| 长岛县| 望都县| 北流市| 平陆县| 广汉市| 金溪县| 临江市| 佛冈县| 阿瓦提县| 北辰区| 福清市|