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ACS Combinatorial Science

ACS Combinatorial Science

IF:3.78
The Journal of Combinatorial Chemistry has been relaunched as ACS Combinatorial Science under the leadership of new Editor-in-Chief M.G. Finn of The Scripps Research Institute. The journal features an expanded scope and will build upon the legacy of the Journal of Combinatorial Chemistry, a highly cited leader in the field.

The E3 ubiquitin ligase ARIH1 promotes antiviral immunity and autoimmunity by inducing mono-ISGylation and oligomerization of cGAS

Published: 10 October 2022 DOI: 10.1038/s41467-022-33671-5
Tian-Chen Xiong,?Ming-Cong Wei,?Fang-Xu Li,?Miao Shi,?Hu Gan,?Zhen Tang,?Hong-Peng Dong,?Tianzi Liuyu,?Pu Gao,?Bo Zhong,?Zhi-Dong Zhang,?Dandan Lin

An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway

Published: 10 March 2022 DOI: 10.1038/s41467-022-28946-w
Fuhui Meng,?Yang Xiao,?Yujia Ji,?Ziyi Sun,?Xiaoming Zhou

The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery

Published: 20 January 2021 DOI: 10.1038/s41467-020-20718-8
Ziyang Fu,?Bin Huang,?Jinle Tang,?Shuyan Liu,?Ming Liu,?Yuxin Ye,?Zhihong Liu,?Yuxian Xiong,?Wenning Zhu,?Dan Cao,?Jihui Li,?Xiaogang Niu,?Huan Zhou,?Yong Juan Zhao,?Guoliang Zhang,?Hao Huang

Targeting USP47 overcomes tyrosine kinase inhibitor resistance and eradicates leukemia stem/progenitor cells in chronic myelogenous leukemia

Published: 4 January 2021 DOI: 10.1038/s41467-020-20259-0
Hu Lei,?Han-Zhang Xu,?Hui-Zhuang Shan,?Meng Liu,?Ying Lu,?Zhi-Xiao Fang,?Jin Jin,?Bo Jing,?Xin-Hua Xiao,?Shen-Meng Gao,?Feng-Hou Gao,?Li Xia,?Li Yang,?Li-Gen Liu,?Wei-Wei Wang,?Chuan-Xu Liu,?Yin Tong,?Yun-Zhao Wu,?Jun-Ke Zheng,?Guo-Qiang Chen,?Li Zhou,?Ying-Li Wu

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model

Published: 12 November 2020 DOI: 10.1038/s41467-020-19547-6
Xufeng Cen,?Yanying Chen,?Xiaoyan Xu,?Ronghai Wu,?Fusheng He,?Qingwei Zhao,?Qiming Sun,?Cong Yi,?Jie Wu,?Ayaz Najafov,?Hongguang Xia

Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease

Published: 4 September 2020 DOI: 10.1038/s41467-020-18233-x
Lifeng Fu,?Fei Ye,?Yong Feng,?Feng Yu,?Qisheng Wang,?Yan Wu,?Cheng Zhao,?Huan Sun,?Baoying Huang,?Peihua Niu,?Hao Song,?Yi Shi,?Xuebing Li,?Wenjie Tan,?Jianxun Qi,?George Fu Gao

Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response

Published: 7 March 2019 DOI: 10.1016/j.molcel.2018.12.006
Johannes H Wilbertz,?Franka Voigt,?Ivana Horvathova,?Gregory Roth,?Yinxiu Zhan,?Jeffrey A Chao

Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation

Published: 30 April 2018 DOI: 10.1038/s41467-018-04072-4
Dingfeng Li,?Juan Zhang,?Ming Wang,?Xiaohui Li,?Huarui Gong,?Huiping Tang,?Lin Chen,?Lili Wan,?Qiang Liu

Selective isolation of gold facilitated by second-sphere coordination with α-cyclodextrin.

Published: 1 January 2013 DOI: 10.1038/ncomms2891
Zhichang Liu, Marco Frasconi, Juying Lei, Zachary J Brown, Zhixue Zhu, Dennis Cao, Julien Iehl, Guoliang Liu, Albert C Fahrenbach, Youssry Y Botros, Omar K Farha, Joseph T Hupp, Chad A Mirkin, J Fraser Stoddart
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