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ChemicalBook >> journal list>> Bioorganic & Medicinal Chemistry
Bioorganic & Medicinal Chemistry

Bioorganic & Medicinal Chemistry

IF:3.3 CiteScore:6.8 Articles:413
Bioorganic & Medicinal Chemistry provides an international forum for the publication of full original research papers and critical reviews on molecular interactions in key biological targets such as receptors, channels, enzymes, nucleotides, lipids and saccharides. The aim of the journal is to promote a better understanding at the molecular level of life processes, and living organisms, as well as the interaction of these with chemical agents. A special feature will be that colour illustrations will be reproduced at no charge to the author, provided that the Editor agrees that colour is essential to the information content of the illustration in question.

D-DARTS: an alternative method for NaV1.5 affinity molecules identification based on dual-drug affinity responsive target stability

Published: 9 October 2025 DOI: 10.1016/j.bmc.2025.118436
Zirui Lü, Xiandong Dai, Huixia Li, Cunlin Wang, Fanhua Meng

Virtual screening, synthesis, optimization and anti-inflammatory activity of novel chromones as specific COX-2 inhibitors

Published: 10 August 2025 DOI: 10.1016/j.bmc.2025.118345
Meng Qin, Mengdi Zhang, Min Wang, Huiqing Guo, Laibing Wang, Jianping Chen, Shuyan Yu, Yuheng Ma

Tc-99m labeled PSMA-617 as a potential SPECT radiotracer for prostate cancer diagnostics: Complexation optimization and its in vitro/vivo evaluation

Published: 1 February 2025 DOI: 10.1016/j.bmc.2024.118058
Kalapaphuk Tachatumvitoon , Charasphat Preuksarattanawut , Thititip Tippayamontri , Piyachai Khomein

Synthesis and structural optimization of oncolytic peptide LTX-315

Published: 15 May 2024 DOI: 10.1016/j.bmc.2024.117760
Min Song , Qing Liu , Jing-Fang Yao , Yu-Tao Wang , Yan-Nan Ma , Huan Xu , Qian-Yao Yu , Zhibo Li , Shan-Shan Du , Yun-Kun Qi

Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors

Published: 1 March 2024 DOI:
Yining Tang , Chunlin Zhuang

Discovery of novel biaryl benzoxazepinones as dual-mode receptor-interacting protein kinase-1 (RIPK1) inhibitors

Published: 1 February 2024 DOI:
YuFeng Xin , Pengcheng Dai , Hongming Shao , Chunlin Zhuang , Jiao Li

Scaffold hopping derived novel benzoxazepinone RIPK1 inhibitors as anti-necroptosis agents

Published: 15 August 2023 DOI: 10.1016/j.bmc.2023.117385
Jiaqin Tang , Yanran Wu , Wenli Zhao, Zhuo Qu, Jianqiang Yu, Zhizhong Wang, Ying Shi

Efficient Delivery of VEGFA mRNA for Promoting Wound Healing via Ionizable Lipid Nanoparticles

Published: 15 January 2023 DOI:
Shuo Dong, Ji Wang, Zongke Guo, Yanhao Zhang, Wenhui Zha, Yang Wang, Chao Liu, Hanlei Xing, Xinsong Li

Design, synthesis, and bioactivity study on Lissodendrins B derivatives as PARP1 inhibitor.

Published: 1 September 2022 DOI: 10.1016/j.bmc.2022.116892
Xinning Liu , Xianfeng Wei , Xionghao Li , Rilei Yu , Tao Jiang , Chenyang Zhao

Molecular similarity guided optimization of novel Nrf2 activators with 1,2,4-oxadiazole core

Published: 15 August 2016 DOI: 10.1016/j.bmc.2016.05.056
Li-Li Xu , Xian Zhang , Zheng-Yu Jiang , Qi-Dong You

Camptothecin: current perspectives

Published: 1 April 2004 DOI: 10.1016/j.bmc.2003.11.036
Craig J. Thomas, Nicolas J. Rahier, Sidney M. Hecht
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