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Cancer Science

Cancer Science

IF:4.5 Articles:406
Cancer Science (formerly Japanese Journal of Cancer Research) is a monthly publication of the Japanese Cancer Association. First published in 1907, the Journal continues to publish original articles, editorials, and letters to the editor, describing original research in the fields of basic, translational and clinical cancer research. The Journal also accepts reports and case reports. Cancer Science aims to present highly significant and timely findings that have a significant clinical impact on oncologists or that may alter the disease concept of a tumor. The Journal will not publish case reports that describe a rare tumor or condition without new findings to be added to previous reports; combination of different tumors without new suggestive findings for oncological research; remarkable effect of already known treatments without suggestive data to explain the exceptional result. Review articles may also be published.

Dauricine Overcomes Osimertinib Resistance in Lung Cancer by Inducing Ferroptosis via Stabilizing SAT1

Published: 8 June 2025 DOI: 10.1111/cas.70113
Biying Men, Zhijie Chen, Haotian Ge, Zhuoying Yang, Liang Yun, Jianjun Jiang, Meijuan Dian, Yujing He, Zehao Zhou, Ruihao Zhang, Tianbao Yan, Zichao Li, Yingxin Zhang, Yongjie He, Junming He, Xuguang Rao, Shuan Rao

Splicing factor TRA2A contributes to esophageal cancer progression via a noncanonical role in lncRNA m6 A methylation

Published: 14 June 2023 DOI:
Mingrong Bei, Shijia Hao, Kai Lin, Qiuyang Chen, Yujie Cai, Xing Zhao, Leiming Jiang, Lirui Lin, Geng Dong, Jianzhen Xu

Histone H1.2 promotes hepatocarcinogenesis by regulating signal transducer and activator of transcription 3 signaling

Published: 16 March 2022 DOI: 10.1111/cas.15336
Qing Wang, Yuchen Chen, Yunhao Xie, Dong Yang, Yuyan Sun, Yangmian Yuan, Hong Chen, Yu Zhang, Kun Huang, Ling Zheng

NLRP4 negatively regulates type I interferon response and influences the outcome in anti‐programmed cell death protein (PD)‐1/PD‐ligand 1 therapy

Published: 20 December 2021 DOI: 10.1111/cas.15243
Hui Wang, Liliang Xia, Cheng-cheng Yao, Hui Dong, Yi Yang, Chong Li, Wen-xiang Ji, Rui-ming Sun, Huang-qi Duan, Wenli Mengzhou, Wei-min Xia, Shu-jun Wang, Ping Ji, Ziming Li, Lei Jiao, Ying Wang, Shun Lu

LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.

Published: 2 December 2021 DOI: 10.1111/cas.15229
Yingqiang Liu, Mengzhen Lai, Shan Li, Yanan Wang, Fang Feng, Tao Zhang, Linjiang Tong, Mengge Zhang, Hao Chen, Yi Chen, Peiran Song, Yan Li, Gang Bai, Yi Ning, Haotian Tang, Yan Fang, Yi Chen, Xiaoyun Lu, Meiyu Geng, Ke Ding, Ker Yu, Hua Xie, Jian Ding

Suppression of multiple anti-apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms

Published: 22 November 2021 DOI: 10.1111/cas.15210
Hisashi Takei, Juan Luiz Coelho-Silva, Cristina Tavares Leal, Adriana Queiroz Arantes Rocha, Thiago Mantello Bianco, Robert S. Welner, Yuta Mishima, Ikei S. Kobayashi, Ann Mullally, Keli Lima, Jo?o Agostinho Machado-Neto, Susumu S. Kobayashi, Lorena Lobo de Figueiredo-Pontes

C644‐0303, a small‐molecule inhibitor of the Wnt/β‐catenin pathway, suppresses colorectal cancer growth, et al. C644‐0303, a small‐molecule inhibitor of the Wnt/β‐catenin pathway, suppresses colorectal cancer growth

Published: 25 August 2021 DOI: 10.1111/cas.15118
Yu Yan, Yidan Zhang, Mengyuan Li, Yazhuo Zhang, Xinxin Zhang, Xiaonan Zhang, Yuting Xu, Wei Wei, Jie Wang, Xiaohan Xu, Qiaoling Song, Chenyang Zhao

Exosomes mediate intercellular transfer of non–autonomous tolerance to proteasome inhibitors in mixed-lineage leukemia

Published: 14 February 2020 DOI: 10.1111/cas.14351
Maolin Ge, Zhi Qiao, Yan Kong, Hui Lu, Han Liu

Promoting Effects of Potassium Dibasic Phosphate on Early-stage Renal Carcinogenesis in Unilaterally Nephrectomized Rats Treated with N-Ethyl-N-hydroxyethylnitrosamine

Published: 1 July 1992 DOI: 10.1111/j.1349-7006.1992.tb01967.x
Yoshio Hiasa, Noboru Konishi, Shingo Nakaoka, Toshimitsu Nakamura, Kiyoji Nishii, Masato Ohshima
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