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International Journal of Molecular Sciences

IF:4.9 CiteScore:8.1 Articles:13472

The International Journal of Molecular Sciences (ISSN 1422-0067) provides an advanced forum for chemistry, molecular physics (chemical physics and physical chemistry) and molecular biology. It publishes research articles, reviews, communications and short notes. Our aim is to encourage scientists to publish their theoretical and experimental results in as much detail as possible. Therefore, there is no restriction on the length of the papers or the number of electronics supplementary files. For articles with computational results, the full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material (including animated pictures, videos, interactive Excel sheets, software executables and others).

Virtual Drug Repositioning as a Tool to Identify Natural Small Molecules That Synergize with Lumacaftor in F508del-CFTR Binding and Rescuing

Published: 14 October 2022 DOI: 10.3390/ijms232012274
Paola Fossa, Matteo Uggeri, Alessandro Orro, Chiara Urbinati, Alessandro Rondina, Maria Milanesi, Nicoletta Pedemonte, Emanuela Pesce, Rita Padoan, Robert C Ford, Xin Meng, Marco Rusnati, Pasqualina D'Ursi

Diflubenzuron Induces Cardiotoxicity in Zebrafish Embryos.

Published: 8 October 2022 DOI: 10.3390/ijms231911932
Xue Han,?Xiaowen Xu,?Tingting Yu,?Meifeng Li,?Yulong Liu,?Jingli Lai,?Huiling Mao,?Chengyu Hu,?Shanghong Wang

Antiviral Drugs Screening for Swine Acute Diarrhea Syndrome Coronavirus

Published: 24 September 2022 DOI: 10.3390/ijms231911250
Yangzhen Chen, Yecheng You, Shuqi Wang, Lin Jiang, Lili Tian, Shaozhou Zhu, Xiaoping An, Lihua Song, Yigang Tong, Huahao Fan

AST-487 Inhibits RET Kinase Driven TERT Expression in Bladder Cancer

Published: 16 September 2022 DOI: 10.3390/ijms231810819
Neeraj Agarwal, Qiong Zhou, Deepak Arya, Sébastien Rinaldetti, Jason Duex, Daniel V LaBarbera, Dan Theodorescu

Dual Inhibition of EGFR and IGF-1R Signaling Leads to Enhanced Antitumor Efficacy against Esophageal Squamous Cancer

Published: 8 September 2022 DOI: 10.3390/ijms231810382
Jia Kang, Zanzan Guo, Haoqi Zhang, Rongqi Guo, Xiaofei Zhu, Xiaofang Guo

Glycidyl Methacrylate-Based Copolymers as Healing Agents of Waterborne Polyurethanes.

Published: 23 July 2022 DOI: 10.3390/ijms23158118
Ioanna Tzoumani, Amaia Soto Beobide, Zacharoula Iatridi, George A Voyiatzis, Georgios Bokias, Joannis K Kallitsis

Nonsteroidal Anti-Inflammatory Drugs as PPARγ Agonists Can Induce PRODH/POX-Dependent Apoptosis in Breast Cancer Cells: New Alternative Pathway in NSAID-Induced Apoptosis

Published: 28 January 2022 DOI: 10.3390/ijms23031510
Adam Kazberuk, Magda Chalecka, Jerzy Palka, Arkadiusz Surazynski

PAR4-Mediated PI3K/Akt and RhoA/ROCK Signaling Pathways Are Essential for Thrombin-Induced Morphological Changes in MEG-01 Cells

Published: 11 January 2022 DOI: 10.3390/ijms23020776
Yunkyung Heo, Hyejin Jeon, Wan Namkung

hnRNPA2B1-Mediated Extracellular Vesicles Sorting of miR-122-5p Potentially Promotes Lung Cancer Progression

Published: 28 November 2021 DOI: 10.3390/ijms222312866
Chuang Li, Fang Qin, Wei Wang, Yifan Ni, Mingyu Gao, Mingxiong Guo, Guihong Sun

Downregulation of MMP-9 Enhances the Anti-Migratory Effect of Cyclophosphamide in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines

Published: 26 November 2021 DOI: 10.3390/ijms222312783
Magdalena Izdebska, Wioletta Zielińska, Adrian Krajewski, Marta Ha?as-Wi?niewska, Klaudia Miko?ajczyk, Maciej Gagat, Alina Grzanka

Synthesis, Properties, and Selected Technical Applications of Magnesium Oxide Nanoparticles: A Review.

Published: 25 November 2021 DOI: 10.3390/ijms222312752
Jaroslav Hornak

The Mechanism of Leptin on Inhibiting Fibrosis and Promoting Browning of White Fat by Reducing ITGA5 in Mice

Published: 16 November 2021 DOI: 10.3390/ijms222212353
Yuexia Liu, Yizhou Li, Juntong Liang, Zhuwen Sun, Qiong Wu, Yongnian Liu, Chao Sun

Cinobufagin Exerts Anticancer Activity in Oral Squamous Cell Carcinoma Cells through Downregulation of ANO1

Published: 7 November 2021 DOI: 10.3390/ijms222112037
Sungwoo Jo, Eunhee Yang, Yechan Lee, Dongkyu Jeon, Wan Namkung

25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses

Published: 1 November 2021 DOI: 10.3390/ijms222111869
Qiaoshuai Lan, Chao Wang, Jie Zhou, Lijue Wang, Fanke Jiao, Yanbo Zhang, Yanxing Cai, Lu Lu, Shuai Xia, Shibo Jiang

Developing Wound Dressings Using 2-deoxy-D-Ribose to Induce Angiogenesis as a Backdoor Route for Stimulating the Production of Vascular Endothelial Growth Factor.

Published: 23 October 2021 DOI: 10.3390/ijms222111437
Serkan Dikici, Muhammad Yar, Anthony J Bullock, Joanna Shepherd, Sabiniano Roman, Sheila MacNeil

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