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Molecular Therapy
Molecular Therapy
IF:12
CiteScore:19.2
Articles:357
Molecular Therapy is the leading journal for research in gene transfer, vector development, stem cell manipulation, and therapeutic interventions. It covers a broad spectrum of topics including genetic and acquired disease correction, vaccine development, pre-clinical validation, safety/efficacy studies, and clinical trials. With a focus on advancing genetics, medicine, and biotechnology, Molecular Therapy publishes peer-reviewed research, reviews, and commentaries to showcase the latest advancements in the field. With an impressive impact factor of 12.4 in 2022, it continues to attract top-tier contributions.
Flavopiridol restores granulopoiesis in experimental models of severe congenital neutropenia
Published: 4 June 2025
DOI: 10.1016/j.ymthe.2024.10.031
Masoud Nasri,?Benjamin Dannenmann,?Larissa Doll,?Betül Findik,?Franka Bernhard,?Sergey Kandabarau,?Maksim Klimiankou,?Meinrad Gawaz,?Claudia Lengerke,?Cornelia Zeidler,?Karl Welte,?Julia Skokowa
Masoud Nasri,?Benjamin Dannenmann,?Larissa Doll,?Betül Findik,?Franka Bernhard,?Sergey Kandabarau,?Maksim Klimiankou,?Meinrad Gawaz,?Claudia Lengerke,?Cornelia Zeidler,?Karl Welte,?Julia Skokowa
Renal tubular epithelial IGFBP7 interacts with PKM2 to drive renal lipid accumulation and fibrosis
Published: 8 May 2025
DOI: 10.1016/j.ymthe.2025.05.013
Ju-Tao Yu,Shuai-Shuai Xie,Xiao-Yu Shen,Zeng Li,Xiao-Wei Hu,Yao Zhang,Ze-Hui Dong,Jia-Nan Wang,Xiang-Yu Li,Yu-Hang Dong,Chao Li,Ming-Lu Ji,Xiao-Guo Suo,Chen Yang,Juan Jin,Wei Wang,Jia-Gen Wen,Ming-Ming Liu,Li Li,Qin Yang,Xiao-Ming Meng
Ju-Tao Yu,Shuai-Shuai Xie,Xiao-Yu Shen,Zeng Li,Xiao-Wei Hu,Yao Zhang,Ze-Hui Dong,Jia-Nan Wang,Xiang-Yu Li,Yu-Hang Dong,Chao Li,Ming-Lu Ji,Xiao-Guo Suo,Chen Yang,Juan Jin,Wei Wang,Jia-Gen Wen,Ming-Ming Liu,Li Li,Qin Yang,Xiao-Ming Meng
Targeting viral suppressor of RNAi confers anti-coronaviral activity
Published: 8 January 2025
DOI: 10.1016/j.ymthe.2024.12.009
Jiyao Chen,?JingFang Mu,?Kangping Zhou,?Yuming Zhang,?Jieling Zhang,?Ting Shu,?Weijuan Shang,?Yujie Ren,?Xi-Qiu Xu,?Leike Zhang,?Shuai Yuan,?Dingyu Zhang,?Kun Cai,?Yang Qiu,?Xi Zhou
Jiyao Chen,?JingFang Mu,?Kangping Zhou,?Yuming Zhang,?Jieling Zhang,?Ting Shu,?Weijuan Shang,?Yujie Ren,?Xi-Qiu Xu,?Leike Zhang,?Shuai Yuan,?Dingyu Zhang,?Kun Cai,?Yang Qiu,?Xi Zhou
Targeting RORγ inhibits the growth and metastasis of hepatocellular carcinoma
Published: 6 March 2024
DOI: 10.1016/j.ymthe.2024.01.032
Qianqian Liu,?Junhua Wang,?Huizi Sun,?Zhenhua Zhang,?Hong Wang,?Shuai Ma,?Chenxi Zhang,?Qianqian Wang,?Guodi Cai,?Jianwei Zheng,?Yichu Nie,?Peiqing Liu,?Junjian Wang
Qianqian Liu,?Junhua Wang,?Huizi Sun,?Zhenhua Zhang,?Hong Wang,?Shuai Ma,?Chenxi Zhang,?Qianqian Wang,?Guodi Cai,?Jianwei Zheng,?Yichu Nie,?Peiqing Liu,?Junjian Wang
Polyphyllin D punctures hypertrophic lysosomes to reverse drug resistance of hepatocellular carcinoma by targeting acid sphingomyelinase
Published: 5 July 2023
DOI: 10.1016/j.ymthe.2023.05.015
Yang Wang,?Yan-Yan Chen,?Gui-Bin Gao,?Yang-Han Zheng,?Nan-Nan Yu,?Lan Ouyang,?Xuejuan Gao,?Nan Li,?Shi-Yuan Wen,?Shangjia Huang,?Qian Zhao,?Langxia Liu,?Mingrong Cao,?Shuixing Zhang,?Jing Zhang,?Qing-Yu He
Yang Wang,?Yan-Yan Chen,?Gui-Bin Gao,?Yang-Han Zheng,?Nan-Nan Yu,?Lan Ouyang,?Xuejuan Gao,?Nan Li,?Shi-Yuan Wen,?Shangjia Huang,?Qian Zhao,?Langxia Liu,?Mingrong Cao,?Shuixing Zhang,?Jing Zhang,?Qing-Yu He
Dual-aptamer-engineered M1 macrophage with enhanced specific targeting and checkpoint blocking for solid-tumor immunotherapy.
Published: 3 August 2022
DOI: 10.1016/j.ymthe.2022.04.015
Husun Qian,?Yixin Fu,?Minkang Guo,?Yu Chen,?Dian Zhang,?Yu Wei,?Fangfang Jin,?Qian Zeng,?Yange Wang,?Chengsen Chai,?Shijia Ding,?Wei Cheng,?Tingmei Chen
Husun Qian,?Yixin Fu,?Minkang Guo,?Yu Chen,?Dian Zhang,?Yu Wei,?Fangfang Jin,?Qian Zeng,?Yange Wang,?Chengsen Chai,?Shijia Ding,?Wei Cheng,?Tingmei Chen