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Nature Cell Biology

IF:19.1 CiteScore:28.4 Articles:219

Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology

Mouse trophectoderm stem cells generated with morula signalling inducers capture an early trophectoderm state

Published: 14 August 2025 DOI: 10.1038/s41556-025-01732-8
Yake Gao, Mingying Li, Wei Guan, Wei Guo, Shu Wei, Fang Yan, Wenrui Han, Xueting Zhang, Tong Yin, Yunkun Dang, Huanhuan Li, José C. R. Silva, Jian Zhang

SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis

Published: 29 October 2024 DOI: 10.1038/s41556-024-01530-8
Songxiao Zhong, Xindi Li, Changhao Li, Haiyan Bai, Jingjing Chen, Lu Gan, Jiyun Zhu, Taerin Oh, Xingxing Yan, Jiaying Zhu, Niankui Li, Hisashi Koiwa, Thomas Meek, Xu Peng, Bin Yu, Zhonghui Zhang, Xiuren Zhang

Full-length GSDME mediates pyroptosis independent from cleavage.

Published: 12 July 2024 DOI: 10.1038/s41556-024-01463-2
Bo Zhou, Zhi-hong Jiang, Meng-ran Dai, Yuan-li Ai, Li Xiao, Chuan-qi Zhong, Liu-Zheng Wu, Qi-tao Chen, Hang-zi Chen, Qiao Wu

SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming

Published: 6 February 2024 DOI: 10.1038/s41556-024-01349-3
Xi Xu, Yanhui Yu, Wenwen Zhang, Weiwei Ma, Chong He, Guo Qiu, Xinyi Wang, Qiong Liu, Minyi Zhao, Jiayi Xie, Fang Tao, John M. Perry, Qifa Liu, Shuan Rao, Xunlei Kang, Meng Zhao, Linjia Jiang

Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition

Published: 2 January 2024 DOI:
Weiwei Cui, Meng Guo, Dong Liu, Peng Xiao, Chuancheng Yang, Haidi Huang, Chunhui Liang, Yinghong Yang, Xiaolong Fu, Yudan Zhang, Jiaxing Liu, Shuang Shi, Jingjing Cong, Zili Han, Yunfei Xu, Lutao Du, Chengqian Yin, Yongchun Zhang, Jinpeng Sun, Wei Gu, Renjie Chai, Shu Zhu, Bo Chu

The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells

Published: 24 July 2023 DOI:
Haisha Liang, Xinyu Ma, Yuanyuan Zhang, Yuheng Liu, Nan Liu, Weiying Zhang, Jianhui Chen, Boqi Liu, Wanqing Du, Xiaohui Liu, Li Yu

PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.

Published: 24 April 2023 DOI: 10.1038/s41556-023-01122-y
Xiaosai Yao, Jing Han Hong, Amrita M. Nargund, Michelle Shu Wen Ng, Hong Lee Heng, Zhimei Li, Peiyong Guan, Masahiro Sugiura, Pek Lim Chu, Loo Chien Wang, Xiaofen Ye, James Qu, Xiu Yi Kwek, Jeffrey Chun Tatt Lim, Wen Fong Ooi, Joanna Koh, Zhenxun Wang, You-Fu Pan, Yan Shan Ong, Kiat-Yi Tan, Jian Yuan Goh, Sheng Rong Ng, Luca Pignata, Dachuan Huang, Alexander Lezhava, Su Ting Tay, Minghui Lee, Xun Hui Yeo, Wai Leong Tam, Sun Young Rha, Shang Li, Ernesto Guccione, Andrew Futreal, Jing Tan, Joe Poh Sheng Yeong, Wanjin Hong, Robert Yauch, Kenneth Tou-En Chang, Radoslaw M. Sobota, Patrick Tan, Bin Tean Teh

BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling

Published: 11 May 2020 DOI: 10.1038/s41556-020-0516-x
Shengyong Yu, Chunhua Zhou, Shangtao Cao, Jiangping He, Baomei Cai, Kaixin Wu, Yue Qin, Xingnan Huang, Lizhan Xiao, Jing Ye, Shuyang Xu, Wenxiu Xie, Junqi Kuang, Shilong Chu, Jing Guo, He Liu, Wei Pang, Lin Guo, Mengying Zeng, Xiaoshan Wang, Rongping Luo, Chen Li, Guoqing Zhao, Bo Wang, Linlin Wu, Jiekai Chen, Jing Liu, Duanqing Pei

Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity.

Published: 4 May 2020 DOI:
Yi Huang, Huanyu Wang, Yize Hao, Hualong Lin, Menghao Dong, Jin Ye, Lei Song, Yunzhi Wang, Qingqing Li, Benjie Shan, Yizhou Jiang, Hongqi Li, Zhiming Shao, Guido Kroemer, Huafeng Zhang, Li Bai, Tengchuan Jin, Chao Wang, Yuting Ma, Yongping Cai, Chen Ding, Suling Liu, Yueyin Pan, Wei Jiang, Rongbin Zhou

Migrasome formation is mediated by assembly of micron-scale tetraspanin macrodomains

Published: 1 August 2019 DOI: 10.1038/s41556-019-0367-5
Yuwei Huang, Ben Zucker, Shaojin Zhang, Sharon Elias, Yun Zhu, Hui Chen, Tianlun Ding, Ying Li, Yujie Sun, Jizhong Lou, Michael M. Kozlov, Li Yu