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Phytomedicine

IF:6.7 CiteScore:10.3 Articles:670

Phytomedicine is a therapy-oriented journal that publishes innovative studies on the efficacy, safety, quality, and mechanisms of action of specified plant extracts, phytopharmaceuticals, and their isolated constituents. This includes clinical, pharmacological, pharmacokinetic, and toxicological studies of herbal medicinal products, preparations, and purified compounds with defined and consistent quality, ensuring reproducible pharmacological activity. Founded in 1994, Phytomedicine aims to focus and stimulate research in this field and establish internationally accepted scientific standards for pharmacological studies, proof of clinical efficacy, and safety of phytomedicines.

Phytochemicals: A potential next generation agent for radioprotection

Published: 1 November 2022 DOI: 10.1016/j.phymed.2022.154188
Bimal Prasad Jit , Subhaswaraj Pattnaik , Rakesh Arya , Rutumbara Dash , Saubhagya Subhadarsini Sahoo , Biswajita Pradhan , Prajna Paramita Bhuyan , Pradyota Kumar Behera , Mrutyunjay Jena , Ashok Sharma , Paban Kumar Agrawala , Rajendra Kumar Behera

Berberine-mediated REDD1 down-regulation ameliorates senescence of retinal pigment epithelium by interrupting the ROS-DDR positive feedback loop

Published: 1 September 2022 DOI: 10.1016/j.phymed.2022.154181
Qingqiu Chen , Guang Xin , Shiyi Li , Yuman Dong , Xiuxian Yu, Chengyu Wan, Zeliang Wei, Yuda Zhu, Kun Zhang, Yilan Wang, Fan Li, Cuicui Zhang, E Wen, Yulong Li, Hai Niu, Wen Huang

Saucerneol attenuates nasopharyngeal carcinoma cells proliferation and metastasis through selectively targeting Grp94

Published: 1 July 2022 DOI:
Yanfang Cheng, Qian Wang, Zhikang Zhang, Chao Zhao, Huihao Zhou, Jun Xu, Qiong Gu

Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin

Published: 1 May 2022 DOI: 10.1016/j.phymed.2022.154018
Congcong Zhang , Dingqi Zhang , Yongli Wang , Linzhang Zhang , Shenglan Qi , Qinqin Fang , Ying Xu , Jiamei Chen , Xuemei Cheng , Ping Liu , Changhong Wang , Wei Liu

Samhwangsasim-tang attenuates neuronal apoptosis and cognitive decline through BDNF-mediated activation of tyrosin kinase B and p75-neurotrophin receptors

Published: 1 May 2022 DOI: 10.1016/j.phymed.2022.153997
Malk Eun Pak , Yeo Jin Park , Hye Jin Yang , Youn-Hwan Hwang , Wei Li , Younghoon Go

Astragaloside IV promotes the angiogenic capacity of adipose-derived mesenchymal stem cells in a hindlimb ischemia model by FAK phosphorylation via CXCR2

Published: 1 February 2022 DOI:
Weiyi Wang , Zekun Shen , Yanan Tang, Bingyi Chen, Jinxing Chen, Jiaxuan Hou, Jiayan Li, Mengzhao Zhang, Shuang Liu, Yifan Mei, Liwei Zhang, Shaoying Lu

Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches

Published: 1 January 2022 DOI: 10.1016/j.phymed.2021.153805
Qiang Sun , Ting Gong , Maolun Liu , Shan Ren , Han Yang , Sha Zeng , Hui Zhao , Li Chen , Tianqi Ming , Xianli Meng , Haibo Xu

Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling

Published: 1 December 2021 DOI: 10.1016/j.phymed.2021.153781
Ke-xin Wang , Guan-hua Du , Xue-mei Qin , Li Gao

Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis

Published: 1 October 2021 DOI:
Ting Xiao , Yuli Wei , Mengqi Cui , Xiaohe Li , Hao Ruan , Liang Zhang , Jiali Bao , Shanfa Ren , Dandi Gao , Ming Wang , Ronghao Sun , Mingjiang Li , Jianping Lin , Dongmei Li , Cheng Yang , Honggang Zhou

Naringenin protects RPE cells from NaIO3-induced oxidative damage in vivo and in vitro through up-regulation of SIRT1

Published: 1 January 2021 DOI: 10.1016/j.phymed.2020.153375
Wenpei Chen , Bingqing Lin , Shichuan Xie , Wei Yang , Junli Lin , Zhaojia Li , Yaxian Zhan , Shuhua Gui , Baoqin Lin

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis

Published: 1 February 2020 DOI: 10.1016/j.phymed.2019.153160
Xingwu Jiang , Si Chen , Qiansen Zhang , Chunyang Yi , Jiacheng He , Xiyun Ye , Mingyao Liu , Weiqiang Lu

Novel steroidal saponin isolated from Trillium tschonoskii maxim. exhibits anti-oxidative effect via autophagy induction in cellular and Caenorhabditis elegans models

Published: 1 December 2019 DOI: 10.1016/j.phymed.2019.153088
An-Guo Wu , Jin-Feng Teng , Vincent Kam-Wai Wong , Xiao-Gang Zhou , Wen-Qiao Qiu , Yong Tang , Jian-Ming Wu , Rui Xiong , Rong Pan , Yi-Ling Wang , Bin Tang , Tian-Yi Ding , Lu Yu , Wu Zeng , Da-Lian Qin , Betty Yuen-Kwan Law

Effect of Euphorbia factor L1 on intestinal barrier impairment and defecation dysfunction in Caenorhabditis elegans

Published: 1 December 2019 DOI: 10.1016/j.phymed.2019.153102
Zhu An , Ji Zonghui , Zhao Jingwei , Zhang Wenjing , Sun Yuqing , Zhang Tao , Gao Shan , Li Guojun , Wang Qi

Amygdalin, quackery or cure?

Published: 15 April 2016 DOI: 10.1016/j.phymed.2016.02.004
Roman A. Blaheta , Karen Nelson , Axel Haferkamp , Eva Juengel

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