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Science Translational Medicine

Science Translational Medicine

IF:14.6 CiteScore:26.7 Articles:309
Science Translational Medicine is an online journal that focuses on publishing research at the intersection of science, engineering, and medicine. The goal of the journal is to promote human health by providing a platform for researchers from various disciplines to communicate their latest advancements in biomedical, translational, and clinical research. The journal aims to address the slow translation of scientific knowledge into effective treatments and health measures. It publishes articles that fill the knowledge gaps between preclinical research and medical applications, with a focus on accelerating the translation of knowledge into new ways of preventing, diagnosing, and treating human diseases. The scope of Science Translational Medicine includes various areas such as cardiovascular disease, immunology/vaccines, metabolism/diabetes/obesity, neuroscience/neurology/psychiatry, cancer, infectious diseases, policy, behavior, bioengineering, chemical genomics/drug discovery, imaging, applied physical sciences, medical nanotechnology, drug delivery, biomarkers, gene therapy/regenerative medicine, toxicology and pharmacokinetics, data mining, cell culture, animal and human studies, medical informatics, and other interdisciplinary approaches to medicine. The target audience of the journal includes researchers and management in academia, government, and the biotechnology and pharmaceutical industries. It is also relevant to physician scientists, regulators, policy makers, investors, business developers, and funding agencies.

An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis

Published: 4 January 2023 DOI: 10.1126/scitranslmed.add3949
Shuang?Wang, Kenneth?Li, Eliana?Pickholz, Ross?Dobie, Kylie P.?Matchett, Neil C.?Henderson, Chris?Carrico, Ian?Driver, Martin?Borch Jensen, Li?Chen, Mathieu?Petitjean, Dipankar?Bhattacharya, Maria I.?Fiel, Xiao?Liu, Tatiana?Kisseleva, Uri?Alon, Miri?Adler, Ruslan?Medzhitov, Scott L.?Friedman

PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma

Published: 23 September 2020 DOI: 10.1126/scitranslmed.aay0152
Tian-Yi Jiang, Yu-Fei Pan, Zheng-Hua Wan, Yun-Kai Lin, Bin Zhu, Zhen-gang Yuan, Yun-Han Ma, Yuan-Yuan Shi, Tian-Mei Zeng, Li-Wei Dong, Ye-Xiong Tan, Hong-Yang Wang
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