Chemical Safety Data Sheet MSDS / SDS
1,1,3-Trichloroacetone
Revision Date:2026-05-30Revision Number:1
Product identifier
- Product name: 1,1,3-Trichloroacetone
- CBnumber: CB1275319
- CAS: 921-03-9
- EINECS Number: 213-063-6
- Synonyms: 1,1,3-Trichloroacetone,1,1,3-TRICHLOROPROPANONE
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
Hazard statements
H314 Causes severe skin burns and eye damage
H330 Fatal if inhaled
H410 Very toxic to aquatic life with long lasting effects
Substance
- Product name: 1,1,3-Trichloroacetone
- Synonyms: 1,1,3-Trichloroacetone,1,1,3-TRICHLOROPROPANONE
- CAS: 921-03-9
- EC number: 213-063-6
- MF: C3H3Cl3O
- MW: 161.41
If inhaled
Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor/ physician.
In case of skin contact
Take off all contaminated clothing immediately. If on skin, rinse well with water. If skin irritation or rash occurs: Get medical advice/ attention.
In case of eye contact
Rinse with plenty of water. If easy to do, remove contact lens, if worn. Immediately call a POISON CENTER or doctor/ physician.
If swallowed
Immediately call a POISON CENTER or doctor/ physician. Rinse mouth.
Most important symptoms and effects, both acute and delayed
None known.
Suitable extinguishing media
Dry powder, Foam, Water spray, Carbon dioxide (CO2)
Specific hazards during fire fighting
No information available.
Specific extinguishing methods
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Immediately evacuate personnel to safe areas. Remove undamaged containers from fire area if it is safe to do so.
Special protective equipment for fire-fighters
Use personal protective equipment.
Personal precautions, protective equipment and emergency procedures
Wear suitable protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Environmental precautions
Should not be released into the environment.
Methods and materials for containment and cleaning up
Collect as much of the spill as possible with a suitable absorbent material.
Handling
Technical measuresPrevent generation of vapor or mist. Take precautionary measures against static discharge. Use explosion-proof equipment.
Local/Total ventilation
Ensure adequate ventilation. Handle product only in closed system or provide appropriate exhaust ventilation at machinery. Use a local exhaust ventilation.
Advice on safe handling
Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not subject to grinding, shock or friction. Wash hands and face thoroughly after handling.
Avoidance of contact
Oxidizing agents, Bases
Storage
Conditions for safe storageKeep container tightly closed. Store in a cool and shaded area. Keep in a well-ventilated place. Keep under inert gas. Store locked up.
Ingredients with workplace control parameters
Contains no substances with occupational exposure limit values.
Engineering measures
Install a closed system or local exhaust.
Also install safety shower and eye bath.
Also install safety shower and eye bath.
Personal protective equipment
Respiratory protectionGas mask
Self-contained breathing apparatus
Eye/face protection
Self-contained breathing apparatus
Safety glasses
Safety goggles
Face-shield
Skin and body protection
Safety goggles
Face-shield
Impervious protective clothing
Hand protection
Impervious gloves *Use personal protective equipment(PPE) approved under appropriate government standards and follow local and national regulations.
Information on basic physicochemical properties
- Physical stateOil
- Appearanceliquid
- Colorcolorless - yellow
- OdorNo data available
- Odor ThresholdNo data available
- pHNo data available
- Melting point/freezing pointNo data available
- Boiling point/boiling range172 °C
- Flash point80 °C
- Evaporation rateNo data available
- FlammabilityNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Lower explosion limit / Lower flammability limit6.3 %(V)
- Vapor pressure30-350Pa at 20-50℃
- Relative density1.53
- Solubility(ies)Chloroform, Methanol
- Water solubilityNo data available
- Solubility in other solventsChloroform, Methanol
- Partition coefficient: n-octanol/water (log value)No data available
- Autoignition temperatureNo data available
- Decomposition temperatureNo data available
- Viscosity, dynamicNo data available
- Viscosity, kinematicNo data available
- Molecular weight161.41 g/mol
Reactivity
No data available
Chemical stability
Stable under normal conditions.
Possibility of hazardous reactions
None under normal processing.
Conditions to avoid
Electrical spark Open flame Exposure to air.
Incompatible materials
Oxidizing agents, Bases
Hazardous decomposition products
Carbon monoxide, Carbon dioxide (CO2), Hydrogen chloride gas
Acute toxicity
Product
Acute oral toxicity
Assessment: The component/mixture is toxic after single ingestion.
Acute inhalation toxicity
Assessment: The component/mixture is extremely toxic after short term inhalation.
Components
1,1,3-Trichloroacetone
Acute oral toxicity
Assessment: The component/mixture is toxic after single ingestion.
Acute inhalation toxicity
LC50 (Mouse): 360 mg/m3 Exposure time: 2 h Test atmosphere: dust/mist Assessment: The component/mixture is extremely toxic after short term inhalation.
LC50 (Rat)
390 mg/m3 Exposure time: 2 h Test atmosphere: dust/mist
Skin corrosion/irritation
Product
Result
Causes burns.
Components
1,1,3-Trichloroacetone
Result
Causes burns.
Serious eye damage/eye irritation
Product
Result
Irreversible effects on the eye
Components
1,1,3-Trichloroacetone
Result
Irreversible effects on the eye
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2.
Germ cell mutagenicity
Classified based on available data. For more details, see section 2.
Carcinogenicity
Classified based on available data. For more details, see section 2.
Reproductive toxicity
Classified based on available data. For more details, see section 2.
STOT-single exposure
Classified based on available data. For more details, see section 2.
STOT-repeated exposure
Classified based on available data. For more details, see section 2.
Repeated dose toxicity
Classified based on available data. For more details, see section 2.
Aspiration toxicity
Classified based on available data. For more details, see section 2.
RTECS No.
UC3840000 (1,1,3-Trichloroacetone)
Ecotoxicity
Product:
Ecotoxicology Assessment
Acute aquatic toxicityVery toxic to aquatic life.
Chronic aquatic toxicity
Very toxic to aquatic life with long lasting effects.
Components:
1,1,3-Trichloroacetone:
Ecotoxicology Assessment
Acute aquatic toxicityVery toxic to aquatic life.
Chronic aquatic toxicity
Very toxic to aquatic life with long lasting effects.
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesDisposal in accordance with local and national regulations. Take precautions against ignition or explode. Entrust disposal to a licensed waste disposal company.
Contaminated packaging
Disposal in accordance with local and national regulations. Before disposal of used container, remove contents completely.
International Regulations
IATA-DGR
Not permitted for transport
IMDG-Code
UN numberUN 3390
Proper shipping name
TOXIC BY INHALATION LIQUID, CORROSIVE, N.O.S.
Class
6.1
Subsidiary risk
8
Packing group
I
EmS Code
F-A, S-B
Domestic regulation
GB 6944/12268
UN numberUN 3390
Proper shipping name
TOXIC BY INHALATION LIQUID, CORROSIVE, N.O.S.
Class
6.1
Subsidiary risk
8
Packing group
I
Measures on the Environmental Administration of New Chemical Substances Registration
Registration/Notification numberB1A232215685
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
Downstream users need to comply with the conditions of safe use of the chemical, understand the environmental and health hazard and risk management measures identified on the SDS as well as the local/national regulations concerning the chemical.
The ingredients of this product are reported in the following inventories
CH BAGREGOn the inventory, or in compliance with the inventory
TSCA
Substance(s) not listed on TSCA inventory
AICS
On the inventory, or in compliance with the inventory
DSL
This product contains the following components that are not on the
Canadian DSL nor NDSL.
1,1,3-Trichloroacetone
ENCS
Canadian DSL nor NDSL.
1,1,3-Trichloroacetone
Not in compliance with the inventory
ISHL
Not in compliance with the inventory
KECI
Not in compliance with the inventory
PICCS
On the inventory, or in compliance with the inventory
IECSC
Not in compliance with the inventory
NZIoC
On the inventory, or in compliance with the inventory
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.