Chemical Safety Data Sheet MSDS / SDS
15(R)-PROSTAGLANDIN F2ALPHA
Revision Date:2026-05-31Revision Number:1
Product identifier
- Product name: 15(R)-PROSTAGLANDIN F2ALPHA
- CBnumber: CB9714380
- CAS: 37658-84-7
- Synonyms: 15(R)-Prostaglandin F2α,(+)-Prostaglandin F2α
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501 Dispose of contents/container to..…
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P370+P378 In case of fire: Use … for extinction.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P308+P313 IF exposed or concerned: Get medical advice/attention.
Hazard statements
H336 May cause drowsiness or dizziness
H361 Suspected of damaging fertility or the unborn child
H319 Causes serious eye irritation
H302 Harmful if swallowed
H225 Highly Flammable liquid and vapour
Substance
- Product name: 15(R)-PROSTAGLANDIN F2ALPHA
- Synonyms: 15(R)-Prostaglandin F2α,(+)-Prostaglandin F2α
- CAS: 37658-84-7
- MF: C20H34O5
- MW: 354.48
Description of first aid measures
General information
Immediately remove any clothing soiled by the product.
After inhalation
Supply fresh air; consult doctor in case of complaints.
After skin contact
Immediately rinse with water.
After eye contact
Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.
After swallowing
If symptoms persist consult doctor.
Most important symptoms and effects, both acute and delayed
No further relevant information available.
Indication of any immediate medical attention and special treatment needed
No further relevant information available.
FIRE-FIGHTING MEASURES
| Fire-fighting measure | Details |
|---|---|
| Suitable extinguishing agents | CO2, extinguishing powder or water spray. Fight larger fires with water spray or alcohol resistant foam. For safety reasons unsuitable extinguishing agents: Water with full jet |
| Special hazards arising from the substance or mixture | No further relevant information available. |
| Protective equipment | No special measures required. |
NFPA 704
2
3
0
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Wear protective equipment. Keep unprotected persons away.
Environmental precautions
Do not allow to enter sewers/ surface or ground water.
Methods and material for containment and cleaning up
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Dispose contaminated material as waste according to section 13.
Ensure adequate ventilation.
Dispose contaminated material as waste according to section 13.
Ensure adequate ventilation.
Protective Action Criteria for Chemicals
PAC-1
79-20-9 Methyl acetate 250 ppm
PAC-2
79-20-9 Methyl acetate 1,700 ppm
PAC-3
79-20-9 Methyl acetate 1 0000* ppm
Reference to other sections
See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.
Precautions for safe handling
Ensure good ventilation/exhaustion at the workplace.
Open and handle receptacle with care.
Prevent formation of aerosols.
Open and handle receptacle with care.
Prevent formation of aerosols.
Information about protection against explosions and fires
Keep ignition sources away - Do not smoke.
Protect against electrostatic charges.
Keep respiratory protective device available.
Protect against electrostatic charges.
Keep respiratory protective device available.
Conditions for safe storage, including any incompatibilities
Storage
Store in accordance with information listed on the product insert
Requirements to be met by storerooms and receptacles
Store in a cool location.
Information about storage in one common storage facility
Not required.
Further information about storage conditions
Keep receptacle tightly sealed.
Store in cool, dry conditions in well sealed receptacles.
Store in cool, dry conditions in well sealed receptacles.
Specific end use(s)
No further relevant information available.
Control parameters
Components with limit values that require monitoring at the workplace:
The following constituent is the only constituent of the product which has a PEL, TLV or other recommended exposure limit.
At this time, the remaining constituent has no known exposure limits.
The following constituent is the only constituent of the product which has a PEL, TLV or other recommended exposure limit.
At this time, the remaining constituent has no known exposure limits.
| 79-20-9 Methyl acetate | |
|---|---|
| PEL | Long-term value: 610 mg/m3, 200 ppm |
| REL | Short-term value: 760 mg/m3, 250 ppm Long-term value: 610 mg/m3, 200 ppm |
| TLV | Short-term value: 757 mg/m3, 250 ppm Long-term value: 606 mg/m3, 200 ppm |
Components with limit values that require monitoring at the workplace
The following constituent is the only constituent of the product which has a PEL, TLV or other recommended exposure limit.
Additional information
The lists that were valid during the creation were used as basis.
Exposure controls
Appropriate engineering controls
No further data; see section 7.
Personal protective equipment
General protective and hygienic measures
Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Store protective clothing separately.
Avoid contact with the eyes.
Avoid contact with the eyes and skin.
Breathing equipment
In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.
Protection of hands
Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
Eye protection
Tightly sealed goggles
Information on basic physicochemical properties
- Evaporation RateNot determined.
- Solids content0.5 %
- VOC content0.00 % 0.0 g/l / 0.00 lb/gal
- Organic solvents99.5 %
- Danger of explosionProduct is not explosive. However, formation of explosive air/vapor mixtures are possible.
- Ignition temperatureProduct is not selfigniting.
- FormLiquid
- Particle characteristicsNot applicable.
- Vapor DensityNot determined.
- Relative DensityNot determined.
- Density at 20 °C (68 °F)0.93 g/cm3 (7.76085 lbs/gal)
- Vapor Pressure at 50 °C (122 °F)800 hPa (600 mm Hg)
- Vapor Pressure at 20 °C (68 °F)220 hPa (165 mm Hg)
- Partition coefficient (n-octanol/water)Not determined.
- Water at 20 °C (68 °F)330 g/l
- Solubility in / Miscibility with10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
- DynamicNot determined.
- SOLUBILITY10 mM Na2CO3: >6.5 mg/ml (from PGF2a)
- KinematicNot determined.
- pHNot determined.
- Decomposition temperatureNot determined.
- Auto igniting454 °C (849.2 °F)
- Flash point-13 °C (8.6 °F)
- Explosion limitsLower: 3.1 Vol %
Upper: 16 Vol % - FlammabilityHighly flammable.
- Boiling point/Boiling range57 °C (134.6 °F)
- Melting point/Melting range-98 °C (-144.4 °F)
- FormulationA solution in methyl acetate
- Odor ThresholdNot determined.
- Molecular Weight354.5 g/mol
- Structural FormulaC20H34O5
- OdorPleasant
- ColorAccording to product specification
- Physical StateLiquid
Reactivity
No further relevant information available.
Chemical stability
Thermal decomposition / conditions to be avoided
No decomposition if used according to specifications.
Possibility of hazardous reactions
No dangerous reactions known.
Conditions to avoid
No further relevant information available.
Incompatible materials
strong oxidizing agents, base
Hazardous decomposition products
carbon dioxide, carbon monoxide
RTECS Number
Information on toxicological effects
Acute toxicity
LD/LC50 values that are relevant for classification:
| Substance / Estimate | Route | Endpoint | Value |
|---|---|---|---|
| 79-20-9 Methyl acetate | Oral | LD50 | 6,482 mg/kg (rat) |
| 79-20-9 Methyl acetate | Inhalative | LC50/4 h | >49.2 mg/l (rabbit) |
Primary irritant effect
on the skin
No irritant effect.
on the eye
Irritating effect.
Sensitization
No sensitizing effects known.
Additional toxicological information
The product shows the following dangers according to internally approved calculation methods for preparations
Irritant
Irritant
Interactive effects
No interactive effects between components are known.
Carcinogenic categories
IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
NTP (National Toxicology Program)
None of the ingredients is listed.
OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.
Alternative sources for toxicological information
No non-standard sources for toxicological information where used.
Toxicity
Aquatic toxicity
No further relevant information available.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Mobility in soil
No further relevant information available.
Results of PBT and vPvB assessment
PBT
Not applicable.
vPvB
Not applicable.
| · | Other adve | rse | effects | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| · | Additional | ecol | ogical | information: | ||||||||||
| · | General no | tes: | ||||||||||||
| Water haza | rd cl | ass 1 ( | Self-assessment): | slightly | hazardous | for | w | ater | ||||||
| Do not allo | w un | diluted | product or large q | uantitie | s of it to re | ach | ground | water, | water | course | or | sewage | ||
| system. |
PBT:
Not applicable.
vPvB:
Not applicable.
Waste treatment methods
Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
Uncleaned packagings
Recommendation
Disposal must be made according to official regulations.
UN-Number
DOT, IMDG, IATA UN1231
UN proper shipping name
DOT, IATA Methyl acetate solution
IMDG METHYL ACETATE solution
IMDG METHYL ACETATE solution
Transport hazard class(es)
DOTClass: 3 Flammable liquids
Label: 3
IMDG, IATA
Label: 3
Class: 3 Flammable liquids
Label: 3
Label: 3
Packing group
DOT, IMDG, IATA II
Environmental hazards
Not applicable.
Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code
Not applicable.
Transport/Additional information
DOT:
Quantity limitations
On passenger aircraft/rail: 5 L
On cargo aircraft only: 60 L
On cargo aircraft only: 60 L
IMDG:
Limited quantities (LQ)
1L
Excepted quantities (EQ)
Code: E2
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 500 ml
Maximum net quantity per inner packaging: 30 ml
Maximum net quantity per outer packaging: 500 ml
IATA:
Remarks
When sold in quantities of less than or equal to 1 mL, or 1 g, with an Excepted Quantity Code of
E1, E2, E4, or E5, this item meets the De Minimis
Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as
Dangerous Goods/Excepted Quantity.
E1, E2, E4, or E5, this item meets the De Minimis
Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as
Dangerous Goods/Excepted Quantity.
Special precautions for user
Warning: Flammable liquids
Hazard identification number (Kemler code)
33
EMS Number
F-E, S-D
Stowage Category
B
UN "Model Regulation"
UN 1231 METHYL ACETATE SOLUTION, 3, II
Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
Sara
| Section 355 (extremely hazardous substances): | None of the ingredients is listed. |
| Section 313 (Specific toxic chemical listings): | None of the ingredients is listed. |
| TSCA (Toxic Substances Control Act): | 79-20-9 Methyl acetate ACTIVE |
| Hazardous Air Pollutants: | None of the ingredients is listed. |
| Chemicals known to cause cancer: | None of the ingredients is listed. |
| Chemicals known to cause reproductive toxicity for females: | None of the ingredients is listed. |
| Chemicals known to cause reproductive toxicity for males: | None of the ingredients is listed. |
| Chemicals known to cause developmental toxicity: | None of the ingredients is listed. |
Carcinogenic categories
| EPA (Environmental Protection Agency): | None of the ingredients is listed. |
TLV (Threshold Limit Value)
None of the ingredients is listed.
NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
Chemical safety assessment
A Chemical Safety Assessment has not been carried out.
Abbreviations and acronyms
IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
VOC: Volatile Organic Compounds (USA, EU)
LC50: Lethal concentration, 50 percent
LD50: Lethal dose, 50 percent
PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety & Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Flammable liquids 2: Flammable liquids – Category 2
Eye irritation 2A: Serious eye damage/eye irritation – Category 2A
Reproductive toxicity 2: Reproductive toxicity – Category 2
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) – Category 3
DOT: US Department of Transportation
IATA: International Air Transport Association
EINECS: European Inventory of Existing Commercial Chemical Substances
ELINCS: European List of Notified Chemical Substances
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
VOC: Volatile Organic Compounds (USA, EU)
LC50: Lethal concentration, 50 percent
LD50: Lethal dose, 50 percent
PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety & Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Flammable liquids 2: Flammable liquids – Category 2
Eye irritation 2A: Serious eye damage/eye irritation – Category 2A
Reproductive toxicity 2: Reproductive toxicity – Category 2
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) – Category 3
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.