Chemical Safety Data Sheet MSDS / SDS
2-tert-Butyl-4,6-dimethylphenol
Revision Date:2026-05-31Revision Number:1
Product identifier
- Product name: 2-tert-Butyl-4,6-dimethylphenol
- CBnumber: CB1311291
- CAS: 1879-09-0
- EINECS Number: 217-533-1
- Synonyms: Topanol A,2-TERT-BUTYL-4,6-DIMETHYLPHENOL
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P501 Dispose of contents/container to..…
P405 Store locked up.
P391 Collect spillage. Hazardous to the aquatic environment
P314 Get medical advice/attention if you feel unwell.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P270 Do not eat, drink or smoke when using this product.
P264 Wash skin thouroughly after handling.
P262 Do not get in eyes, on skin, or on clothing.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Hazard statements
H302 Harmful if swallowed
H310 Fatal in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H411 Toxic to aquatic life with long lasting effects
H373 May cause damage to organs through prolonged or repeated exposure
Substance
- Product name: 2-tert-Butyl-4,6-dimethylphenol
- Synonyms: Topanol A,2-TERT-BUTYL-4,6-DIMETHYLPHENOL
- CAS: 1879-09-0
- EC number: 217-533-1
- MF: C12H18O
- MW: 178.27
First Aid Measures
General adviceIf symptoms persist, call a physician. Do not breathe dust/fume/gas/mist/vapors/spray. Do not get in eyes, on skin, or on clothing.
Eye contact
Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. If symptoms persist, call a physician.
Skin Contact
Consult a physician if necessary. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Wash contaminated clothing before reuse.
Wash off immediately with plenty of water. If skin irritation persists, call a physician.
Immediate medical attention is not required.
Inhalation
Wash off immediately with plenty of water. If skin irritation persists, call a physician.
Immediate medical attention is not required.
Remove to fresh air Call a physician If breathing is irregular or stopped, administer artificial respiration Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation
Artificial respiration and/or oxygen may be necessary Immediate medical attention is not required Move to fresh air in case of accidental inhalation of vapors If symptoms persist, call a physician
Ingestion
Artificial respiration and/or oxygen may be necessary Immediate medical attention is not required Move to fresh air in case of accidental inhalation of vapors If symptoms persist, call a physician
Rinse mouth. Drink plenty of water. If symptoms persist, call a physician. Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Call a physician.
Self-protection of the first aider
Use personal protective equipment as required.
Most important symptoms and effects, both acute and delayed
SymptomsNo information available.
Indication of any immediate medical attention and special treatment needed
Note to physiciansTreat symptomatically.
Suitable Extinguishing Media
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.
Specific hazards arising from the chemical
Specific hazards arising from the chemicalNo information available.
Hazardous combustion products
Carbon oxides.
Explosion data
Sensitivity to Mechanical ImpactNo information available.
Sensitivity to Static Discharge
No information available.
Protective equipment and precautions for firefighters
Protective equipment and precautions for firefightersAs in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
NFPA 704
2
1
0
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal precautionsUse personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak.
Environmental precautions
Environmental precautionsPrevent entry into waterways, sewers, basements or confined areas. Do not flush into surface water or sanitary sewer system. Prevent further leakage or spillage if safe to do so.
Prevent product from entering drains. See Section 12 for additional Ecological Information.
Prevent product from entering drains. See Section 12 for additional Ecological Information.
Methods and material for containment and cleaning up
Methods for containmentPrevent further leakage or spillage if safe to do so.
Methods for cleaning up
Cover liquid spill with sand, earth or other non-combustible absorbent material. Dam up.
Use personal protective equipment as required. Take up mechanically, placing in appropriate containers for disposal. Clean contaminated surface thoroughly. Soak up with inert absorbent material. Pick up and transfer to properly labeled containers.
Use personal protective equipment as required. Take up mechanically, placing in appropriate containers for disposal. Clean contaminated surface thoroughly. Soak up with inert absorbent material. Pick up and transfer to properly labeled containers.
Precautions for safe handling
Advice on safe handlingAvoid contact with skin, eyes or clothing. Use personal protective equipment as required.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Use with local exhaust ventilation.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Use with local exhaust ventilation.
Conditions for safe storage, including any incompatibilities
Storage ConditionsKeep container tightly closed in a dry and well-ventilated place. Keep out of the reach of children. Keep containers tightly closed in a cool, well-ventilated place. Keep in properly labeled containers. Store at room temperature.
Incompatible materials
None known based on information supplied.
Control parameters
Exposure GuidelinesThis product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Appropriate engineering controls
Engineering ControlsShowers
Eyewash stations
Ventilation systems
Eyewash stations
Ventilation systems
Individual protection measures, such as personal protective equipment
Eye/face protectionTight sealing safety goggles. Face protection shield.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended.
Information on basic physicochemical properties
- Physical Stateliquid
- AppearanceNo information available
- OdorNo information available
- pHNo information available
- Melting point/freezing point22 °C
- Boiling point249 °C
- Flash point112 °C
- Liquid Density0.92 g/cm3
- Evaporation rateNo information available
- Upper flammability limitsNo information available
- Lower flammability limitNo information available
- Vapor pressure19.95 mmHg
- Vapor density1
- Specific gravity0.96
- Water solubility120mg/L at 20℃
- Solubility in other solventsNo information available
- Partition coefficient4.52
- Autoignition temperatureNo information available
- Decomposition temperatureNo information available
- Kinematic viscosityNo information available
- Explosive propertiesNo information available
- Oxidizing propertiesNo information available
- Density and/or relative density0,917 g/cm3
- SolubilityInsoluble in water
- ColourWhite or Colorless to Light yellow
Reactivity
Not applicable
Chemical stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing.
Hazardous polymerization
No information available.
Conditions to avoid
Extremes of temperature and direct sunlight.
Incompatible materials
Strong oxidizing agents.
Hazardous Decomposition Products
Carbon oxides.
Information on likely routes of exposure
InhalationClassified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.
Information on toxicological effects
SymptomsClassified based on available data. For more details, see section 2.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic ToxicityAvoid repeated exposure.
Numerical measures of toxicity - Product Information
Unknown acute toxicityClassified based on available data. For more details, see section 2
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
The following values are calculated based on chapter 3.1 of the GHS document
500 mg/kg
Ecotoxicity
Very toxic to aquatic life with long lasting effects
0% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
0% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
Persistence and degradability
No information available.
Bioaccumulation
No information available.
Mobility
No information available.
Disposal of wastes
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging
Do not reuse container.
Other Information
Waste codes should be assigned by the user based on the application for which the product was used.
DOT
UN/ID noUN2810
Hazard Class
6.1
Packing Group
I
Toxic liquids, organic, n.o.s.
UN2810, Toxic liquids, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I
Emergency Response Guide Number
Toxic liquids, organic, n.o.s.
UN2810, Toxic liquids, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I
153
IMDG
UN/ID noUN2810
Hazard Class
6.1
Packing Group
I
Toxic liquid, organic, n.o.s.
UN2810, Toxic liquid, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I, Marine pollutant
Special Provisions
Toxic liquid, organic, n.o.s.
UN2810, Toxic liquid, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I, Marine pollutant
274, 315
EmS-No
F-A, S-A
IATA
UN/ID noUN2810
Hazard Class
6.1
Packing Group
I
Toxic liquid, organic, n.o.s.
UN2810, Toxic liquid, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I
ERG Code
Toxic liquid, organic, n.o.s.
UN2810, Toxic liquid, organic, n.o.s. (2-tert-butyl-4,6-dimethylphenol), 6.1, I
6L
International Inventories
All of the components in the product are on the following Inventory lists
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) Australia (AICS) South Korea (KECL): China (IECSC)
ENCS (Japan): Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) Australia (AICS) South Korea (KECL): China (IECSC)
ENCS (Japan): Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| 2-tert-butyl-4,6-dimethylphen ol | X | X | - | X | - | X | X | X | X | X |
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazardYes
Chronic Health Hazard
No
Fire hazard
No
Sudden release of pressure hazard
No
Reactive hazard
No
CWA (Clean Water Act)
This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).
CFR 122.42).
US State Regulations
California Proposition 65
This product does not contain any Proposition 65 chemicals.
U.S. State Right-to-Know Regulations
This product does not contain any substances regulated by state right-to-know regulations
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.