Chemical Safety Data Sheet MSDS / SDS

2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox

Revision Date:2026-05-31Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: 2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox
CBnumber: CB8111696
CAS: 35511-15-0
EINECS Number: 252-601-4
Synonyms: methyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide,2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P501 Dispose of contents/container to..…

P273 Avoid release to the environment.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P270 Do not eat, drink or smoke when using this product.

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P271 Use only outdoors or in a well-ventilated area.

P264 Wash skin thouroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378 In case of fire: Use … for extinction.

P391 Collect spillage. Hazardous to the aquatic environment

P337+P313 IF eye irritation persists: Get medical advice/attention.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313 IF SKIN irritation occurs: Get medical advice/attention.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P403+P235 Store in a well-ventilated place. Keep cool.

P405 Store locked up.

Hazard statements

H315 Causes skin irritation

H319 Causes serious eye irritation

H371 May cause damage to organs

H370 Causes damage to organs

H372 Causes damage to organs through prolonged or repeated exposure

H335 May cause respiratory irritation

H410 Very toxic to aquatic life with long lasting effects

H227 Combustible liquid

SECTION 3: Composition/information on ingredients

Substance

Product name: 2-Methyl-4-hydroxy-2H-1,2-benzisothiazine-3-carboxylic acid ethyl ester-1,1-diox
Synonyms: methyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide,2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-3-CARBOXYLIC METHYL ESTER-1,1-DIOXIDE
CAS: 35511-15-0
EC number: 252-601-4
MF: C11H11NO5S
MW: 269.27

SECTION 4: First aid measures

4.1 Description of first-aid measures

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

4.2 Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

4.3 Indication of any immediate medical attention and special treatment needed

No data available

4.4 Notes to physician

No data available

SECTION 5: Firefighting measures

5.1 Extinguishing media

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

5.2 Special hazards arising from the substance or mixture

Carbon oxides
Nitrogen oxides (NOx)
Sulfur oxides
Combustible.

5.3 Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.
Suppress (knock down) gases/vapors/mists with a water spray jet.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: Protective equipment see section 8.
For personal protection see section 8.

6.2 Environmental precautions

No special precautionary measures necessary.

6.3 Methods and materials for containment and cleaning up

Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

6.4 Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry.

Storage stabilityRecommended storage temperature

2 - 8 °C

Storage class

Storage class (TRGS 510): 11: Combustible Solids

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

8.2 Exposure controls

Appropriate engineering controls

Change contaminated clothing. Wash hands after working with substance.

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L

Respiratory protection

required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Control of environmental exposure

No special precautionary measures necessary.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

a) Physical statesolid
b) ColorWhite to Pale Yellow
c) OdorNo data available
d) Melting point/freezing pointMelting point: 165 °C
e) Initial boiling point and boiling range439.9±55.0 °C(Predicted)
f) Flammability (solid, gas)No data available
g) Upper/lower flammability or explosive limitsNo data available
h) Flash pointNot applicable
i) Autoignition temperatureNo data available
j) Decomposition temperatureNo data available
k) pHNo data available
l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available
m) Water solubilityat 25 °C - (calculated)slightly soluble
n) Partition coefficient n-octanol/waterlog Pow: 1.170 at 25 °C - Bioaccumulation is not expected.
o) Vapor pressureNo data available
p) Density1.514±0.06 g/cm3(Predicted)
Relative density1.514±0.06 g/cm3(Predicted)
q) Relative vapor densityNo data available
r) Particle characteristicsNo data available
s) Explosive propertiesNot classified as explosive.
t) Oxidizing propertiesnone
SolubilityChloroform (Slightly), Methanol (Slightly)

9.2 Other safety information

No data available

SECTION 10: Stability and reactivity

10.1 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

10.2 Possibility of hazardous reactions

No data available

10.3 Conditions to avoid

no information available

10.4 Incompatible materials

Strong oxidizing agents

10.5 Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information