Chemical Safety Data Sheet MSDS / SDS
Ethyl silicate
Revision Date:2026-05-31Revision Number:1
Product identifier
- Product name: Ethyl silicate
- CBnumber: CB3854369
- CAS: 78-10-4
- EINECS Number: 201-083-8
- Synonyms: 78-10-4,TEOS
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H226 Flammable liquid and vapour
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
Substance
- Product name: Ethyl silicate
- Synonyms: 78-10-4,TEOS
- CAS: 78-10-4
- EC number: 201-083-8
- MF: C8H20O4Si
- MW: 208.33
4.1 Description of first-aid measures
No data available
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides silicon oxides
Combustible.
Combustible.
5.3 Advice for firefighters
No data available
NFPA 704
2
3
1
| HEALTH | 2 | Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 1 | Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
For personal protection see section 8.
6.2 Environmental precautions
No data available
6.3 Methods and materials for containment and cleaning up
No data available
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Moisture sensitive. Handle and store under inert gas.
Storage class
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters8.2 Exposure controls
Skin protectionFull contact
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.2 mm
Break through time: 30 min
Material tested: P (KCL 743 / Aldrich Z677388, Size M)
Control of environmental exposure
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.2 mm
Break through time: 30 min
Material tested: P (KCL 743 / Aldrich Z677388, Size M)
Prevent product from entering drains.
Information on basic physicochemical properties
- a) Physical stateliquid, clear
- b) Colorcolorless
- c) OdorNo data available
- d) Melting point/freezing pointMelting point: -82.5 °C at ca.1,013 hPa
- e) Initial boiling point and boiling range165 - 166 °C at 1,013 hPa
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 23 %(V)
Lower explosion limit: 1.3 %(V) - h) Flash point45 °C - closed cup - DIN 51755 Part 1
- i) Autoignition temperature222 °C at 960.8 hPa
- j) Decomposition temperatureNo data available
- k) pH7 (20°C)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: 0.6 mPa.s at 20 °C - m) Water solubility1.49 g/l at 23 °C at 7 hPa - soluble
- n) Partition coefficient n-octanol/waterlog Pow: 3.18 at 40 °C - Bioaccumulation is not expected.
- o) Vapor pressure< 1 hPa at 20 °C
- p) Density0.94 g/cm3 at 20 °C - DIN 51757
- Relative density0.933 g/mL at 20 °C(lit.)
- q) Relative vapor density7.2 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- SolubilitySoluble in ethanol and 2-propanol.
- Dielectric constant4.1（20℃）
9.2 Other safety information
Relative vapor density7.19 - (Air = 1.0)
10.1 Chemical stability
No data available
10.2 Possibility of hazardous reactions
No data available
10.3 Conditions to avoid
No data available
10.4 Incompatible materials
Strong oxidizing agents, Strong acids
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - > 2,500 mg/kg (OECD Test Guideline 423)
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
LD50 Oral - Rat - 6,270 mg/kg
Remarks: (RTECS)
LC50 Inhalation - Rat - male - 4 h - 10 mg/l - vapor (OECD Test Guideline 403)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Symptoms: mucosal irritations, Cough, Shortness of breath, Inhalation may lead to the formation of oedemas in the respiratory tract., Possible damages:, damage of respiratory tract
LD50 Dermal - Rabbit - 5,878 mg/kg
Remarks: (RTECS)
Skin corrosion/irritation
Symptoms: Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract.
LD50 Oral - Rat - 6,270 mg/kg
Remarks: (RTECS)
LC50 Inhalation - Rat - male - 4 h - 10 mg/l - vapor (OECD Test Guideline 403)
Remarks: (Regulation (EC) No 1272/2008, Annex VI)
Symptoms: mucosal irritations, Cough, Shortness of breath, Inhalation may lead to the formation of oedemas in the respiratory tract., Possible damages:, damage of respiratory tract
LD50 Dermal - Rabbit - 5,878 mg/kg
Remarks: (RTECS)
Skin - Rabbit
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: No skin irritation - 4 h (OECD Test Guideline 404)
Remarks: Causes serious eye irritation.
(Regulation (EC) No 1272/2008, Annex VI)
Respiratory or skin sensitization
(Regulation (EC) No 1272/2008, Annex VI)
Buehler Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 406)
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay)
Result: negative
Carcinogenicity
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: Mutagenicity (Salmonella typhimurium - reverse mutation assay)
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Gavage - NOAEL (No observed adverse effect level) - 10 - 50 mg/kg
RTECS: VV9450000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After uptake of large quantities:
Tiredness narcosis
Damage to:
Kidney
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Liver - Irregularities - Based on Human Evidence
RTECS: VV9450000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After uptake of large quantities:
Tiredness narcosis
Damage to:
Kidney
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Liver - Irregularities - Based on Human Evidence
12.1 Toxicity
Toxicity to fish semi-static test LC50 - Danio rerio (zebra fish) - > 245 mg/l - 96 h (Regulation (EC) No. 440/2008, Annex, C.1)
Toxicity to daphnia flow-through test EC50 - Daphnia magna (Water flea) - > 75 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 100 mg/l - 3 h (OECD Test Guideline 209)
Toxicity to daphnia flow-through test EC50 - Daphnia magna (Water flea) - > 75 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae static test ErC50 - Pseudokirchneriella subcapitata - > 100 mg/l - 72 h (OECD Test Guideline 201)
Toxicity to bacteria static test EC50 - activated sludge - > 100 mg/l - 3 h (OECD Test Guideline 209)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 98 % - Readily biodegradable.
(Directive 67/548/EEC Annex V, C.4.A.)
Result: 98 % - Readily biodegradable.
(Directive 67/548/EEC Annex V, C.4.A.)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
14.1 UN number
ADR/RID: 1292
IMDG: 1292
IATA-DGR: 1292
IMDG: 1292
IATA-DGR: 1292
14.2 UN proper shipping name
ADR/RID: TETRAETHYL SILICATE
IMDG: TETRAETHYL SILICATE
IATA-DGR: Tetraethyl silicate
IMDG: TETRAETHYL SILICATE
IATA-DGR: Tetraethyl silicate
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: III
IMDG: III
IATA-DGR: III
IMDG: III
IATA-DGR: III
14.5 Environmental hazards
ADR/RID: yes
IMDG Marine pollutant: yes
IATA-DGR: no
IMDG Marine pollutant: yes
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
Strong oxidizing agents, Strong acids
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.