Chemical Safety Data Sheet MSDS / SDS
Piperonyl chloride
Revision Date:2026-05-31Revision Number:1
Product identifier
- Product name: Piperonyl chloride
- CBnumber: CB0358033
- CAS: 20850-43-5
- EINECS Number: 244-081-2
- Synonyms: 5-(chloromethyl)benzo[d][1,3]dioxole,piperonyl chloride
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
Hazard statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Substance
- Product name: Piperonyl chloride
- Synonyms: 5-(chloromethyl)benzo[d][1,3]dioxole,piperonyl chloride
- CAS: 20850-43-5
- EC number: 244-081-2
- MF: C8H7ClO2
- MW: 170.59
First Aid Measures
General adviceConsult a physician if necessary. Remove to fresh air.
Eye contact
Wash with plenty of water.
Skin Contact
Wash skin with soap and water.
Inhalation
Remove to fresh air If breathing is difficult, give oxygen If not breathing, give artificial respiration
Ingestion
Never give anything by mouth to an unconscious person. Clean mouth with water.
Most important symptoms and effects, both acute and delayed
SymptomsNo information available.
Indication of any immediate medical attention and special treatment needed
Note to physiciansTreat symptomatically.
Suitable Extinguishing Media
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.
Specific hazards arising from the chemical
Specific hazards arising from the chemicalThermal decomposition can lead to release of toxic/corrosive gases and vapors.
Hazardous combustion products
Carbon oxides. Phosgene.
Explosion data
Sensitivity to Mechanical ImpactNo information available.
Sensitivity to Static Discharge
No information available.
Protective equipment and precautions for firefighters
Protective equipment and precautions for firefightersAs in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Personal precautions, protective equipment and emergency procedures
Personal precautionsEnsure adequate ventilation, especially in confined areas.
Environmental precautions
Environmental precautionsSee Section 12 for additional Ecological Information.
Methods and material for containment and cleaning up
Methods for containmentPrevent further leakage or spillage if safe to do so.
Methods for cleaning up
Pick up and transfer to properly labeled containers.
Precautions for safe handling
Advice on safe handlingThermal decomposition can lead to release of toxic/corrosive gases and vapors.
Conditions for safe storage, including any incompatibilities
Storage ConditionsKeep containers tightly closed in a dry, cool and well-ventilated place. Store at room temperature.
Incompatible materials
None known based on information supplied.
Control parameters
Exposure Guidelines.
Other Information
Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d 962 (11th Cir., 1992).
| Dichloromethane | TWA: 50 ppm | TWA: 25 ppm | IDLH: 2300 ppm |
|---|---|---|---|
| 75-09-2 | (vacated) TWA: 500 ppm (vacated) STEL: 2000 ppm 5 min in any 3 h (vacated) Ceiling: 1000 ppm STEL: 125 ppm see 29 CFR 1910.1052 |
Appropriate engineering controls
Engineering ControlsShowers
Eyewash stations
Ventilation systems
Eyewash stations
Ventilation systems
Individual protection measures, such as personal protective equipment
Eye/face protectionWear safety glasses with side shields (or goggles).
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
Handle in accordance with good industrial hygiene and safety practice.
Information on basic physicochemical properties
- Physical Stateliquid
- AppearanceNo information available
- OdorNo information available
- pHNo information available
- Melting point/freezing pointNo information available
- Boiling point97 °C
- Flash point116 °C
- Liquid Density1.31 g/mL
- Evaporation rateNo information available
- Upper flammability limitsNo information available
- Lower flammability limitNo information available
- Vapor pressureNo information available
- Vapor densityNo information available
- Specific gravityNo information available
- Water solubilityNo information available
- Solubility in other solventsNo information available
- Partition coefficient1.47
- Autoignition temperatureNo information available
- Decomposition temperatureNo information available
- Kinematic viscosityNo information available
- Explosive propertiesNo information available
- Oxidizing propertiesNo information available
- Density and/or relative density1.32
- SolubilityChloroform, Methanol
Reactivity
Not applicable
Chemical stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing.
Hazardous polymerization
No information available.
Conditions to avoid
Extremes of temperature and direct sunlight.
Incompatible materials
Strong oxidizing agents.
Hazardous Decomposition Products
Carbon oxides. Phosgene.
Information on likely routes of exposure
InhalationClassified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.
Information on toxicological effects
SymptomsClassified based on available data. For more details, see section 2.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic ToxicityMay cause adverse liver effects. Target Organ Effects Central Vascular System (CVS), Central nervous system, Eyes, Liver, Lungs, Skin. Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.
Chemical name ACGIH IARC NTP OSHA
Dichloromethane A3 Group2A Reasonably Anticipated X 75-09-2
Numerical measures of toxicity - Product Information
Unknown acute toxicity50% of the mixture consists of ingredient(s) of unknown toxicity
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
The following values are calculated based on chapter 3.1 of the GHS document
1600 mg/kg
ATEmix (inhalation-dust/mist)
76 mg/l
Ecotoxicity
| Chemical name | Algae/aquatic plants | Fish | Toxicity to Microorganisms | Crustacea |
|---|---|---|---|---|
| Dichloromethane 75-09-2 | 500: 72 h Pseudokirchneriella subcapitata mg/L EC50 500: 96 h Pseudokirchneriella subcapitata mg/L EC50 | 193: 96 h Lepomis macrochirus mg/L LC50 flow-through 193: 96 h Lepomis macrochirus mg/L LC50 static 262 - 855: 96 h Pimephales promelas mg/L LC50 static 140.8 - 277.8: 96 h Pimephales promelas mg/L LC50 flow-through | - | 190: 48 h Daphnia magna mg/L EC50 1532 - 1847: 48 h Daphnia magna mg/L EC50 Static |
Dichloromethane 500: 72 h 193: 96 h Lepomis
- 190: 48 h Daphnia magna
Pimephales promelas mg/L
Persistence and degradability No information available. Bioaccumulation No information available. Mobility No information available.
Dichloromethane
1.25 75-09-2
Disposal of wastes
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging
Do not reuse container.
California Hazardous Waste Status
This product contains one or more substances that are listed with the State of California as a hazardous waste.
| Chemical name | California Hazardous Waste Status |
|---|---|
| Dichloromethane 75-09-2 | Toxic |
DOT
UN/ID noUN1593
Hazard Class
6.1
Packing Group
III
Proper shipping name
Dichloromethane Reportable Quantity (RQ) (Dichloromethane: RQ (kg)= 0.454)
Description
UN1593, Dichloromethane, 6.1, III
Emergency Response Guide Number
160
IMDG
UN/ID noUN1593
Hazard Class
6.1
Packing Group
III
Proper shipping name
Dichloromethane
Description
UN1593, Dichloromethane, 6.1, III
EmS-No
F-A, S-A
IATA
UN/ID noUN1593
Hazard Class
6.1
Packing Group
III
Proper shipping name
Dichloromethane
Description
UN1593, Dichloromethane, 6.1, III
ERG Code
6L
International Inventories
All of the components in the product are on the following Inventory lists
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) ENCS (Japan):
X - Listed
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
TSCA (United States): Canada (DSL/NDSL) Europe (EINECS/ELINCS/NLP) ENCS (Japan):
X - Listed
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| Dichloromethane | X | X | - | X | - | X | X | X | X | X |
| 3,4-Methylenedioxybenzyl chloride | X | - | X | X | - | X | - | - | - | - |
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| Dichloromethane | X | X | - | X | - | X | X | X | X | X |
| 3,4-Methylenedioxybenzyl | X | - | X | X | - | X | - | - | - | chloride |
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazardYes
Chronic Health Hazard
Yes
Fire hazard
No
Sudden release of pressure hazard
No
Reactive hazard
No
CWA (Clean Water Act)
This product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42).
| Chemical name | CWA - Reportable Quantities | CWA - Toxic Pollutants | CWA - Priority Pollutants | CWA - Hazardous Substances |
|---|---|---|---|---|
| Dichloromethane 75-09-2 | X | X |
US State Regulations
California Proposition 65
This product contains the following Proposition 65 chemicals.
| Chemical name California Proposition 65 |
|---|
| Chemical name |
| Dichloromethane - 75-09-2 |
U.S. State Right-to-Know Regulations
| Chemical name | New Jersey | Massachusetts | Pennsylvania |
|---|---|---|---|
| Dichloromethane 75-09-2 | X | X | X |
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.