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ChemicalBook >> CAS DataBase List >> 11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE

$38 - $2230
Product name: 11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE
CAS: 102394-31-0
MF: C24H31N5O2
MW: 421.54
EINECS:
MDL Number:MFCD00864743
Synonyms:11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE;AF-DX 116;6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one,5,11-dihydro-11-((2-((diethylamino)m ;ethyl)-7-piperidinyl)acetyl)- ;11-((2-((Diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-(6H)-pyrido[2.3-b][1.4]benzodiazepin-6-one;6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-;6H-Pyrido(2,3-B)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-((2-((diethylamino)methyl)-7-piperidinyl)acetyl)-;Brn 4212983

Price53 Properties Safety Information Description

53 prices

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aablocks
ACHEMBLOCK
Alichem
ApexBio Technology
Biosynth
Cayman Chemical
ChemScene
Crysdot
Sigma-Aldrich
Tocris
TRC
Usbiological

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10
5mg
1mg
50
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25mg
50mg
100mg
250MG
1g
5g

Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One
Packaging5mg
Price$81
Updated2026-05-25
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Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One
Packaging10mg
Price$119
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One
Packaging25mg
Price$218
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One
Packaging50mg
Price$337
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One
Packaging100mg
Price$528
Updated2026-05-25
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Manufactureraablocks
Product numberAA00078W
Product description11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One ≥98%
Packaging1mg
Price$38
Updated2026-05-25
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ManufacturerACHEMBLOCK
Product numberX203156
Product descriptionAF-DX 116 98.00%
Packaging250MG
Price$960
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberX203156
Product descriptionAF-DX 116 98.00%
Packaging100MG
Price$505
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberX203156
Product descriptionAF-DX 116 98.00%
Packaging25MG
Price$175
Updated2026-05-27
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ManufacturerAlichem
Product number102394310
Product description11-(2-(2-((Diethylamino)methyl)piperidin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one
Packaging5g
Price$2185.4
Updated2021-12-16
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ManufacturerAlichem
Product number102394310
Product description11-(2-(2-((Diethylamino)methyl)piperidin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one
Packaging1g
Price$912.6
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6598
Product descriptionAF-DX 116
Packaging10mg
Price$251
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB6598
Product descriptionAF-DX 116
Packaging50mg
Price$1053
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB6598
Product descriptionAF-DX 116
Packaging50mg
Price$1053
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB6598
Product descriptionAF-DX 116
Packaging5mg
Price$165
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB6598
Product descriptionAF-DX 116
Packaging1mg
Price$58
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One	5mg	$81	2026-05-25	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One	10mg	$119	2026-05-25	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One	25mg	$218	2026-05-25	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One	50mg	$337	2026-05-25	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One	100mg	$528	2026-05-25	Buy
aablocks	AA00078W	11-(2-(2-((Diethylamino)Methyl)Piperidin-1-yl)Acetyl)-5H-Benzo[e]Pyrido[3,2-b][1,4]Diazepin-6(11H)-One ≥98%	1mg	$38	2026-05-25	Buy
ACHEMBLOCK	X203156	AF-DX 116 98.00%	250MG	$960	2026-05-27	Buy
ACHEMBLOCK	X203156	AF-DX 116 98.00%	100MG	$505	2026-05-27	Buy
ACHEMBLOCK	X203156	AF-DX 116 98.00%	25MG	$175	2026-05-27	Buy
Alichem	102394310	11-(2-(2-((Diethylamino)methyl)piperidin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one	5g	$2185.4	2021-12-16	Buy
Alichem	102394310	11-(2-(2-((Diethylamino)methyl)piperidin-1-yl)acetyl)-5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one	1g	$912.6	2021-12-16	Buy
ApexBio Technology	B6598	AF-DX 116	10mg	$251	2021-12-16	Buy
ApexBio Technology	B6598	AF-DX 116	50mg	$1053	2021-12-16	Buy
ApexBio Technology	B6598	AF-DX 116	50mg	$1053	2026-05-06	Buy
ApexBio Technology	B6598	AF-DX 116	5mg	$165	2026-05-06	Buy
ApexBio Technology	B6598	AF-DX 116	1mg	$58	2026-05-06	Buy

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Properties

Boiling point :573.2±45.0 °C(Predicted)
Density :1.171
storage temp. :room temp
solubility :DMSO: soluble5mg/mL (clear solution; warmed)
pka :11.29±0.20(Predicted)
form :powder
color :white to beige
InChIKey :UBRKDAVQCKZSPO-UHFFFAOYSA-N
SMILES :CCN(CC)CC1CCCCN1CC(=O)N2c3ccccc3C(=O)Nc4cccnc24

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P233	Keep container tightly closed.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304	IF INHALED:
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362	Take off contaminated clothing and wash before reuse.
P403	Store in a well-ventilated place.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

AF-DX 116 is a selective mAChR M2 antagonist. Ki values are 64, 417, 786, 211 and 5130 nM for human recombinant M2, M1, M3, M4 and M5 muscarinic receptors, respectively.

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11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE

Properties

Safety Information

Description

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