BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-
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- $12 - $1450
- Product name: BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-
- CAS: 1054543-47-3
- MF: C33H25F6N3O3
- MW: 625.56
- EINECS:604-604-1
- MDL Number:MFCD19443178
- Synonyms:BenzaMide, 4-[[2-[3,5-bis(trifluoroMethyl)phenyl]-4,5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-;Apoptosis Activator VII, Apoptozole;6-BROMO-4-CHLOROQUINOLINE HYDROCHLORIDE (1:1);5-bis(trifluoroMethyl)phenyl]-4;5-bis(4-Methoxyphenyl)-1H-iMidazol-1-yl]Methyl]-;Apoptosis Activator VII, Apoptozole - CAS 1054543-47-3 - Calbiochem;4-({2-[3,5-Bis(trifluoromethyl)phenyl]-4,5-bis(4-methoxyphenyl)-1 H-imidazol-1-yl}methyl)benzamide;Apoptozole,Apoptosis Activator VII
56 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 25mg
- 10mM*1mLinDMSO(Solution)
- 50.00mg
- 10mM*1mLinDMSO
- 50mg
- 100.00mg
- 100MG
- 200mg
- 250.00mg
- 250MG
- 1g
- 10 mg
- Manufactureraablocks
- Product numberAA008TM5
- Product descriptionApoptozole 99%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TM5
- Product descriptionApoptozole 99%
- Packaging5mg
- Price$22
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TM5
- Product descriptionApoptozole 99%
- Packaging10mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TM5
- Product descriptionApoptozole 99
- Packaging200mg
- Price$455
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50937
- Product descriptionApoptozole 98%
- Packaging250MG
- Price$320
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50937
- Product descriptionApoptozole 98%
- Packaging250MG
- Price$320
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50937
- Product descriptionApoptozole 98%
- Packaging100MG
- Price$190
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberP50937
- Product descriptionApoptozole 98%
- Packaging100MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number1922DC
- Product descriptionApoptozole
- Packaging25mg
- Price$459
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102708
- Product descriptionApoptozole 98+%
- Packaging50mg
- Price$131
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102708
- Product descriptionApoptozole 98+%
- Packaging5mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA102708
- Product descriptionApoptozole 98+%
- Packaging10mg
- Price$77
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0316515
- Product description4-[[2-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4,5-BIS-(4-METHOXYPHENYL)-1H-IMIDAZOL-1-YL]METHYL]BENZAMIDE 95.00%
- Packaging5MG
- Price$501.61
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4803
- Product descriptionApoptozole
- Packaging50mg
- Price$654
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4803
- Product descriptionApoptozole
- Packaging25mg
- Price$369
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4803
- Product descriptionApoptozole
- Packaging10mg
- Price$75
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TM5 | Apoptozole 99% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA008TM5 | Apoptozole 99% | 5mg | $22 | 2026-05-28 | Buy |
| aablocks | AA008TM5 | Apoptozole 99% | 10mg | $31 | 2026-05-28 | Buy |
| aablocks | AA008TM5 | Apoptozole 99 | 200mg | $455 | 2026-05-28 | Buy |
| ACHEMBLOCK | P50937 | Apoptozole 98% | 250MG | $320 | 2026-05-25 | Buy |
| ACHEMBLOCK | P50937 | Apoptozole 98% | 250MG | $320 | 2026-05-27 | Buy |
| ACHEMBLOCK | P50937 | Apoptozole 98% | 100MG | $190 | 2026-05-25 | Buy |
| ACHEMBLOCK | P50937 | Apoptozole 98% | 100MG | $190 | 2026-05-27 | Buy |
| AK Scientific | 1922DC | Apoptozole | 25mg | $459 | 2021-12-16 | Buy |
| Ambeed | A102708 | Apoptozole 98+% | 50mg | $131 | 2021-12-16 | Buy |
| Ambeed | A102708 | Apoptozole 98+% | 5mg | $59 | 2021-12-16 | Buy |
| Ambeed | A102708 | Apoptozole 98+% | 10mg | $77 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0316515 | 4-[[2-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-4,5-BIS-(4-METHOXYPHENYL)-1H-IMIDAZOL-1-YL]METHYL]BENZAMIDE 95.00% | 5MG | $501.61 | 2021-12-16 | Buy |
| ApexBio Technology | C4803 | Apoptozole | 50mg | $654 | 2021-12-16 | Buy |
| ApexBio Technology | C4803 | Apoptozole | 25mg | $369 | 2021-12-16 | Buy |
| ApexBio Technology | C4803 | Apoptozole | 10mg | $75 | 2026-05-06 | Buy |
Properties
Melting point :225-228°C
Boiling point :703.5±70.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :White solid
pka :15.98±0.50(Predicted)
color :White
InChIKey :ZIMMTPFXOMAJTQ-UHFFFAOYSA-N
SMILES :C(N)(=O)C1=CC=C(CN2C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=NC(C3=CC=C(OC)C=C3)=C2C2=CC=C(OC)C=C2)C=C1
Boiling point :703.5±70.0 °C(Predicted)
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :White solid
pka :15.98±0.50(Predicted)
color :White
InChIKey :ZIMMTPFXOMAJTQ-UHFFFAOYSA-N
SMILES :C(N)(=O)C1=CC=C(CN2C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=NC(C3=CC=C(OC)C=C3)=C2C2=CC=C(OC)C=C2)C=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Apoptozole is an inhibitor of heat shock protein 70 (Hsp70; 65% inhibition at 200 μM) that acts by blocking its ATPase activity. It does not act on Hsp40, Hsp60, or Hsp90. Apoptozole dose-dependently induces apoptosis in cancer cells (IC50 = 5-7 μM). It prevents the association of Hsp70 with apoptotic protease-activating factor 1 and triggers caspase activation in HeLa cells. Apoptozole (10 mg/kg, i.p.) prevents the growth of A549, RKO, and HeLa cell xenografts in mice without significant loss of body weight.Related product price
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