5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
![5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine price.](/CAS/GIF/1134156-31-2.gif)
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- $14 - $4725
- Product name: 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
- CAS: 1134156-31-2
- MF: C25H23Cl2N7O4
- MW: 556.4
- EINECS:
- MDL Number:MFCD18086892
- Synonyms:VER 155008;4-((((2R,3S,4R,5R)-5-(6-aMino-8-((3,4-dichlorobenzyl)aMino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methoxy)Methyl)benzonitrile;8-(3,4-Dichlorobenzyl)aMino-5'-O-(4-cyanobenzyl)adenosine;4-{(2R,3S,4R,5R)-5-[6-aMino-8-(3,4-dichlorobenzylaMino)purin-9-yl]-3,4-dihydroxytetrahydrofuran-2-ylMethoxyMethyl}benzonitrile;VER 155088;5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine;VER-155008, ≥98% (HPLC);8-(3,4-Dichlorobenzyl)amino-5’-O-(4-cyanobenzyl)adenosine, VER155008
71 prices
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Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 25mg
- 250mg
- 500mg
- 1g
- 10
- 50
- 10mM*1mLinDMSO
- 1.00g
- 10mM(in1mLDMSO)
- 1mg
- 5mg
- 10mg
- 50MG
- 10mM(in 1mL DMSO)
- 100mg
- 5G
- 10G
- Manufactureraablocks
- Product numberAA0008ET
- Product descriptionVER-155008 ≥98%(HPLC)
- Packaging100mg
- Price$319
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0008ET
- Product descriptionVER-155008 98%
- Packaging10mg
- Price$49
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0008ET
- Product descriptionVER-155008 98%
- Packaging5mg
- Price$28
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA0008ET
- Product descriptionVER-155008 98%
- Packaging1mg
- Price$14
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number2290AA
- Product description5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
- Packaging1mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001088
- Product descriptionVER 155008 99.00%
- Packaging5MG
- Price$206.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001088
- Product descriptionVER 155008 99.00%
- Packaging10MG
- Price$721.59
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001088
- Product descriptionVER 155008 99.00%
- Packaging50MG
- Price$1327.97
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001088
- Product descriptionVER 155008 99.00%
- Packaging5G
- Price$3054.98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001088
- Product descriptionVER 155008 99.00%
- Packaging10G
- Price$4498.73
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4387
- Product descriptionVER155008
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4387
- Product descriptionVER155008
- Packaging10mM(in 1mL DMSO)
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4387
- Product descriptionVER 155008
- Packaging10mg
- Price$88
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4387
- Product descriptionVER 155008
- Packaging10mM(in1mLDMSO)
- Price$94
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4387
- Product descriptionVER 155008
- Packaging50mg
- Price$226
- Updated2026-05-06
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1608
- Product descriptionVER 155008
- Packaging5mg
- Price$104.5
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0008ET | VER-155008 ≥98%(HPLC) | 100mg | $319 | 2026-05-25 | Buy |
| aablocks | AA0008ET | VER-155008 98% | 10mg | $49 | 2026-05-25 | Buy |
| aablocks | AA0008ET | VER-155008 98% | 5mg | $28 | 2026-05-25 | Buy |
| aablocks | AA0008ET | VER-155008 98% | 1mg | $14 | 2026-05-25 | Buy |
| AK Scientific | 2290AA | 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine | 1mg | $108 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001088 | VER 155008 99.00% | 5MG | $206.8 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001088 | VER 155008 99.00% | 10MG | $721.59 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001088 | VER 155008 99.00% | 50MG | $1327.97 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001088 | VER 155008 99.00% | 5G | $3054.98 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001088 | VER 155008 99.00% | 10G | $4498.73 | 2021-12-16 | Buy |
| ApexBio Technology | A4387 | VER155008 | 10mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A4387 | VER155008 | 10mM(in 1mL DMSO) | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A4387 | VER 155008 | 10mg | $88 | 2026-05-06 | Buy |
| ApexBio Technology | A4387 | VER 155008 | 10mM(in1mLDMSO) | $94 | 2026-05-06 | Buy |
| ApexBio Technology | A4387 | VER 155008 | 50mg | $226 | 2026-05-06 | Buy |
| Axon Medchem | Axon1608 | VER 155008 | 5mg | $104.5 | 2026-05-19 | Buy |
Properties
Boiling point :856.3±75.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :13.04±0.70(Predicted)
form :powder
color :white to light brown
InChIKey :ZXGGCBQORXDVTE-UMCMBGNQSA-N
SMILES :O(CC1=CC=C(C#N)C=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2NCC2=CC=C(Cl)C(Cl)=C2)[C@H](O)[C@@H]1O
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :13.04±0.70(Predicted)
form :powder
color :white to light brown
InChIKey :ZXGGCBQORXDVTE-UMCMBGNQSA-N
SMILES :O(CC1=CC=C(C#N)C=C1)C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2NCC2=CC=C(Cl)C(Cl)=C2)[C@H](O)[C@@H]1O
Safety Information
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Description
VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells.More related product prices
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![5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine](https://img.chemicalbook.com/ProductImageEN/2018-12/small/110edfa5-4508-4f59-9b59-a130c147c852.png){kind=small}
