N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-Morpholin-4-yl-propyl)-pyriMidine-2,4-diaMine
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- $31 - $1200
- Product name: N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-Morpholin-4-yl-propyl)-pyriMidine-2,4-diaMine
- CAS: 1380432-32-5
- MF: C25H30N6O
- MW: 430.55
- EINECS:-0
- MDL Number:MFCD23143628
- Synonyms:EHOP-016;N4-(9-ETHYL-9H-CARBAZOL-3-YL)-N2-(3-MORPHOLIN-4-YL-PROPYL)-PYRIMIDINE-2,4-DIAMINE;N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-Morpholin-4-yl-propyl)-pyriMidine-2,4-diaMine;N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine;N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine Ehop-016;EHop-016, >=98%;EHOP016; EHOP-016; EHOP 016; EHOP016; EHOP-016; EHOP 016.;EHOP 016;EHOP016;4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine
50 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- Axon Medchem
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 10mg
- 5
- 5mg
- 25
- 25mg
- 50mg
- 100mg
- 200mg
- 250MG
- 1g
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98%
- Packaging25mg
- Price$96
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98%
- Packaging50mg
- Price$167
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98%
- Packaging100mg
- Price$279
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98
- Packaging200mg
- Price$435
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98%
- Packaging10mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CEZ
- Product descriptionEHop-016 98%
- Packaging5mg
- Price$31
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ237957
- Product descriptionEHop-016 98%
- Packaging250MG
- Price$670
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ237957
- Product descriptionEHop-016 98%
- Packaging100MG
- Price$335
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberZ237957
- Product descriptionEHop-016 98%
- Packaging25MG
- Price$125
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ96436
- Product descriptionEHOP-016
- Packaging5mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206639
- Product descriptionEHop-016 98+%
- Packaging50mg
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206639
- Product descriptionEHop-016 98+%
- Packaging5mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA206639
- Product descriptionEHop-016 98+%
- Packaging10mg
- Price$58
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2351
- Product descriptionEHop016 99%
- Packaging10mg
- Price$93.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2351
- Product descriptionEHop 016
- Packaging50mg
- Price$291.5
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2351
- Product descriptionEHop 016
- Packaging10mg
- Price$93.5
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009CEZ | EHop-016 98% | 25mg | $96 | 2026-05-28 | Buy |
| aablocks | AA009CEZ | EHop-016 98% | 50mg | $167 | 2026-05-28 | Buy |
| aablocks | AA009CEZ | EHop-016 98% | 100mg | $279 | 2026-05-28 | Buy |
| aablocks | AA009CEZ | EHop-016 98 | 200mg | $435 | 2026-05-28 | Buy |
| aablocks | AA009CEZ | EHop-016 98% | 10mg | $49 | 2026-05-28 | Buy |
| aablocks | AA009CEZ | EHop-016 98% | 5mg | $31 | 2026-05-28 | Buy |
| ACHEMBLOCK | Z237957 | EHop-016 98% | 250MG | $670 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z237957 | EHop-016 98% | 100MG | $335 | 2026-05-27 | Buy |
| ACHEMBLOCK | Z237957 | EHop-016 98% | 25MG | $125 | 2026-05-27 | Buy |
| AK Scientific | J96436 | EHOP-016 | 5mg | $48 | 2021-12-16 | Buy |
| Ambeed | A206639 | EHop-016 98+% | 50mg | $99 | 2021-12-16 | Buy |
| Ambeed | A206639 | EHop-016 98+% | 5mg | $44 | 2021-12-16 | Buy |
| Ambeed | A206639 | EHop-016 98+% | 10mg | $58 | 2021-12-16 | Buy |
| Axon Medchem | Axon2351 | EHop016 99% | 10mg | $93.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon2351 | EHop 016 | 50mg | $291.5 | 2026-05-19 | Buy |
| Axon Medchem | Axon2351 | EHop 016 | 10mg | $93.5 | 2026-05-19 | Buy |
Properties
Boiling point :633.9±65.0 °C(Predicted)
Density :1.27
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :7.30±0.10(Predicted)
form :powder
color :white to beige
InChIKey :AFTZZRFCMOAFCR-UHFFFAOYSA-N
SMILES :CCn1c2ccccc2c3cc(Nc4ccnc(NCCCN5CCOCC5)n4)ccc13
Density :1.27
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :7.30±0.10(Predicted)
form :powder
color :white to beige
InChIKey :AFTZZRFCMOAFCR-UHFFFAOYSA-N
SMILES :CCn1c2ccccc2c3cc(Nc4ccnc(NCCCN5CCOCC5)n4)ccc13
Safety Information
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Description
EHop-016 is an inhibitor of the small Rho GTPases Rac1 and Rac3. It inhibits Rac1 activity in MDA-MB-435 breast cancer cells with an IC50 value of 1.1 μM in a Rac1 activation assay. At a concentration of 1 μM, EHop-016 inhibits 58% of Rac3 activity, and it inhibits Cdc42 activity but only at higher concentrations (5-10 μM). It also increases Rho GTPase RhoA activity ~1.3-fold at concentrations greater than 2 μM. EHop-016 (2-4 μM) inhibits Rac-regulated functions in MDA-MB-435 cells, including lamellipodia formation and serine/threonine p21-activated kinase 1 (PAK1)-mediated cell migration. In a nude mouse model of breast cancer metastasis, EHop-016 (25 mg/kg) significantly lowers mammary fat pad tumor growth, metastasis, and angiogenesis. It also inhibits mutant receptor tyrosine kinase (KIT)-induced growth in systemic mastocytosis and acute myeloid leukemia (AML) cells (≥2.5 μM).More related product prices
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Suppliers and manufacturers
career henan chemical co
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
BOC Sciences
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Nanjing Doge Biomedical Technology Co., Ltd
Hangzhou MolCore BioPharmatech Co.,Ltd.
$1.00
4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine CAS:1380432-32-5
4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine CAS:1380432-32-5
