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ChemicalBook >> CAS DataBase List >> 4-(Difluoromethoxy)nitrobenzene

4-(Difluoromethoxy)nitrobenzene

4-(Difluoromethoxy)nitrobenzene price.
  • $8 - $1475.1
  • Product name: 4-(Difluoromethoxy)nitrobenzene
  • CAS: 1544-86-1
  • MF: C7H5F2NO3
  • MW: 189.12
  • EINECS:
  • MDL Number:MFCD00085009
  • Synonyms:BUTTPARK 45\10-48;Anisole,α,α-difluoro-p-nitro- ;Benzene,1-(difluoromethoxy)-4-nitro- ;Difluoromethyl4-nitrophenylether ;p-Nitrophenyldifluoromethylether ;1-(DIFLUOROMETHOXY)-4-NITROBENZENE;4-(DIFLUOROMETHOXY)NITROBENZENE;4-NITRO-ALPHA,ALPHA-DIFLUOROANISOLE
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  • Manufactureraablocks
  • Product numberAA003D0B
  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging25g
  • Price$21
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003D0B
  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging5g
  • Price$12
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003D0B
  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging1g
  • Price$8
  • Updated2026-05-28
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  • ManufacturerActivate Scientific
  • Product numberAS92615
  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging5g
  • Price$29
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS92615
  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging25g
  • Price$93
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
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  • Product description4-(Difluoromethoxy)nitrobenzene 97%
  • Packaging100g
  • Price$336
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product number4830AD
  • Product description4-(Difluoromethoxy)nitrobenzene
  • Packaging1g
  • Price$63
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1544861
  • Product description4-(Difluoromethoxy)nitrobenzene
  • Packaging250mg
  • Price$489.6
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1544861
  • Product description4-(Difluoromethoxy)nitrobenzene
  • Packaging500mg
  • Price$806.85
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  • ManufacturerAlichem
  • Product number1544861
  • Product description4-(Difluoromethoxy)nitrobenzene
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  • Product description4-(Difluoromethoxy)nitrobenzene 97%
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  • ManufacturerAmbeed
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  • Product description4-(Difluoromethoxy)nitrobenzene 97%
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  • Updated2021-12-16
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  • ManufacturerAmbeed
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  • Product description4-(Difluoromethoxy)nitrobenzene 97%
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  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0022333
  • Product description4-(DIFLUOROMETHOXY)NITROBENZENE 95.00%
  • Packaging5G
  • Price$912.29
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0022333
  • Product description4-(DIFLUOROMETHOXY)NITROBENZENE 95.00%
  • Packaging2.5G
  • Price$796.77
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003D0B 4-(Difluoromethoxy)nitrobenzene 97% 25g $21 2026-05-28 Buy
aablocks AA003D0B 4-(Difluoromethoxy)nitrobenzene 97% 5g $12 2026-05-28 Buy
aablocks AA003D0B 4-(Difluoromethoxy)nitrobenzene 97% 1g $8 2026-05-28 Buy
Activate Scientific AS92615 4-(Difluoromethoxy)nitrobenzene 97% 5g $29 2026-06-04 Buy
Activate Scientific AS92615 4-(Difluoromethoxy)nitrobenzene 97% 25g $93 2026-06-04 Buy
Activate Scientific AS92615 4-(Difluoromethoxy)nitrobenzene 97% 100g $336 2026-06-04 Buy
AK Scientific 4830AD 4-(Difluoromethoxy)nitrobenzene 1g $63 2021-12-16 Buy
Alichem 1544861 4-(Difluoromethoxy)nitrobenzene 250mg $489.6 2021-12-16 Buy
Alichem 1544861 4-(Difluoromethoxy)nitrobenzene 500mg $806.85 2021-12-16 Buy
Alichem 1544861 4-(Difluoromethoxy)nitrobenzene 1g $1475.1 2021-12-16 Buy
Ambeed A179728 4-(Difluoromethoxy)nitrobenzene 97% 100g $203 2021-12-16 Buy
Ambeed A179728 4-(Difluoromethoxy)nitrobenzene 97% 25g $64 2021-12-16 Buy
Ambeed A179728 4-(Difluoromethoxy)nitrobenzene 97% 5g $20 2021-12-16 Buy
Ambeed A179728 4-(Difluoromethoxy)nitrobenzene 97% 1g $9 2021-12-16 Buy
American Custom Chemicals Corporation HCH0022333 4-(DIFLUOROMETHOXY)NITROBENZENE 95.00% 5G $912.29 2021-12-16 Buy
American Custom Chemicals Corporation HCH0022333 4-(DIFLUOROMETHOXY)NITROBENZENE 95.00% 2.5G $796.77 2021-12-16 Buy

Properties

Melting point :37-40 °C (lit.)
Boiling point :108 °C
Density :1.384±0.06 g/cm3(Predicted)
Flash point :>230 °F
storage temp. :2-8°C
form :powder to lump
color :Light yellow to Brown to Dark green
FreezingPoint :31.0 to 34.0 ℃
InChI :1S/C7H5F2NO3/c8-7(9)13-6-3-1-5(2-4-6)10(11)12/h1-4,7H
InChIKey :SVGGBARCOQPYMV-UHFFFAOYSA-N
SMILES :[O-][N+](=O)c1ccc(OC(F)F)cc1
CAS DataBase Reference :1544-86-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-(Difluoromethoxy)nitrobenzene is an industrial chemical that can be used to make 4-fluoro-3-pyridinol (F3P), a compound that has potential as a new drug for the treatment of cancer. The synthesis of F3P begins with the reaction of 4-(difluoromethoxy)nitrobenzene and potassium hydroxide in methanol, which yields 4-fluoro-3-hydroxypyridine. This product is then reacted with ammonia gas and pyridine to yield F3P. The final step involves heating the product at high temperature with nitric acid, which yields nitrobenztriazole.

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