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ChemicalBook >> CAS DataBase List >> 17(R)-Resolvin D3

17(R)-Resolvin D3

17(R)-Resolvin D3 price.
  • $169 - $1347
  • Product name: 17(R)-Resolvin D3
  • CAS: 1427475-53-3
  • MF: C22H32O5
  • MW: 376.49
  • EINECS:
  • MDL Number:
  • Synonyms:17(R)-Resolvin D3;5,7,9,13,15,19-Docosahexaenoic acid, 4,11,17-trihydroxy-, (4S,5Z,7E,9E,11R,13Z,15E,17R,19Z)-
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 10μg
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number9002880
  • Product description17(R)-Resolvin D3 ≥90%
  • Packaging10μg
  • Price$169
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002880
  • Product description17(R)-Resolvin D3 ≥90%
  • Packaging25μg
  • Price$400
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002880
  • Product description17(R)-Resolvin D3 ≥90%
  • Packaging50μg
  • Price$758
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number9002880
  • Product description17(R)-Resolvin D3 ≥90%
  • Packaging100μg
  • Price$1347
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 9002880 17(R)-Resolvin D3 ≥90% 10μg $169 2026-04-30 Buy
Cayman Chemical 9002880 17(R)-Resolvin D3 ≥90% 25μg $400 2026-04-30 Buy
Cayman Chemical 9002880 17(R)-Resolvin D3 ≥90% 50μg $758 2026-04-30 Buy
Cayman Chemical 9002880 17(R)-Resolvin D3 ≥90% 100μg $1347 2026-04-30 Buy

Properties

Boiling point :609.2±55.0 °C(Predicted)
Density :1.101±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: unstable; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
pka :4.56±0.10(Predicted)

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

17(R)-Resolvin D3 (17(R)-RvD3) is an aspirin-triggered epimer of resolvin D3 .1 It is produced from docosahexaenoic acid (DHA; ) by COX-2 in the presence of aspirin via a 17(R)-hydroperoxy DHA (17(R)-HDHA; ) intermediate and has been found in mouse inflammatory exudates.1,2 17(R)-RvD3 reduces transmigration of isolated human polymorphonuclear cells (PMNs) and induces efferocytosis of apoptotic PMNs by macrophages.2 17(R)-RvD3 (10 ng/animal) reduces transmigration of neutrophils into the peritoneal cavity, as well as decreases the levels of IL-6 and increases the levels of IL-10 in inflammatory exudate in a mouse model of zymosan-induced peritonitis. It activates GPR32 in a β-arrestin reporter assay and increases phagocytosis to a greater degree in CHO cells overexpressing GPR32 compared to mock-transfected cells. 17(R)-RvD3 increases phagocytosis of etoposide-generated tumor cell debris by monocyte-derived macrophages in H460 human lung carcinoma cells in a concentration-dependent manner.3 It also inhibits tumor growth in a mouse model of Lewis lung carcinoma when administered at a dose of 0.6 μg/kg per day.

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