N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide
![N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide price.](/CAS/GIF/184036-34-8.gif)
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- $186 - $2400
- Product name: N- (4- chloro- 3- methyl- oxazol- 5- yl)- 2- [2- (6- methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophene- 3- sulfonamide
- CAS: 184036-34-8
- MF: C18H15ClN2O6S2
- MW: 454.9
- EINECS:
- MDL Number:MFCD00945687
- Synonyms:N-(4-chloro-3-methyl-2,3-dihydrooxazol-5-yl)-2-(2-(6-methylbenzo[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide;N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide;N-(4-Chloro-3-methyl-oxazol-5-yl)-2-[2-(6-methylbenzo[1,3]dioxol-5-yl)acetyl]thiophene-3-sulfo;N-(4-Chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d]-[1,3]dioxol-5-yl)acetyl)thiophene-3;N-(4-chloro-3-methyl-oxazol-5-yl)-2-[2-(6-methylbenzo[1,3]dioxol-5-yl)acetyl]thiophene-3-sulfonamide;D07171;Sitax;N- (4- chloro- 3- Methyl- oxazol- 5- yl)- 2- [2- (6- Methylbenzo[1,3]dioxol- 5- yl)acetyl]- thiophen
31 prices
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Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- Chemenu
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 25MG
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging1mg
- Price$186
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging5mg
- Price$193
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging10mg
- Price$215
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging20mg
- Price$279
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging100mg
- Price$436
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging50mg
- Price$350
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging1g
- Price$1043
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039SD
- Product descriptionN-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90%
- Packaging500mg
- Price$708
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging1MG
- Price$360
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging1MG
- Price$360
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging100MG
- Price$2400
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging100MG
- Price$2400
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging5MG
- Price$940
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging5MG
- Price$940
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging25MG
- Price$1560
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberS78000
- Product descriptionSitaxentan 97%
- Packaging25MG
- Price$1560
- Updated2026-05-27
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 1mg | $186 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 5mg | $193 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 10mg | $215 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 20mg | $279 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 100mg | $436 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 50mg | $350 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 1g | $1043 | 2026-05-28 | Buy |
| aablocks | AA0039SD | N-(4-chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide 90% | 500mg | $708 | 2026-05-28 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 1MG | $360 | 2026-05-25 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 1MG | $360 | 2026-05-27 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 100MG | $2400 | 2026-05-25 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 100MG | $2400 | 2026-05-27 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 5MG | $940 | 2026-05-25 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 5MG | $940 | 2026-05-27 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 25MG | $1560 | 2026-05-25 | Buy |
| ACHEMBLOCK | S78000 | Sitaxentan 97% | 25MG | $1560 | 2026-05-27 | Buy |
Properties
Melting point :42-45°
Boiling point :663.9±65.0 °C(Predicted)
Density :1.558
storage temp. :2-8°C
solubility :DMSO
form :Powder
pka :4.96±0.10(Predicted)
Boiling point :663.9±65.0 °C(Predicted)
Density :1.558
storage temp. :2-8°C
solubility :DMSO
form :Powder
pka :4.96±0.10(Predicted)
Safety Information
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Description
Sitaxsentan is a selective endothelin-A (ETA) receptor antagonist launched for the treatment of patients with pulmonary arterial hypertension (PAH), to improve exercise capacity. It is the second ET receptor antagonist to be marketed for this indication behind bosentan. PAH encompasses a heterogeneous group of disorders characterized by inappropriate overactivation of the endothelin system and is characterized by a progressive increase in pulmonary vascular resistance resulting from vascular remodeling, vasoconstriction, and cellular proliferation. Endothelin-1 (ET-1), a potent vasoconstrictor and smooth muscle mitogen, is a key contributor to the acceleration of the disease, and its effects are mediated through activation of ETA and ETB receptors. ETA receptors are found primarily on smooth muscle cells and, when activated, induce vasoconstriction and cellular proliferation. ETB receptors are expressed in both pulmonary vascular endothelial cells and smooth muscle cells, and their activation is associated with the renal and pulmonary clearance of ET.More related product prices
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