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ChemicalBook >> CAS DataBase List >> 2,2-Dimethyl-1,3-dioxane-4,6-dione

2,2-Dimethyl-1,3-dioxane-4,6-dione

2,2-Dimethyl-1,3-dioxane-4,6-dione price.
  • $6 - $4225.87
  • Product name: 2,2-Dimethyl-1,3-dioxane-4,6-dione
  • CAS: 2033-24-1
  • MF: C6H8O4
  • MW: 144.13
  • EINECS:217-992-8
  • MDL Number:MFCD00006638
  • Synonyms:'MELDRUM'S ACID';LABOTEST-BB LT00233174;2,2-DiMethyl-1,3-dioxane-4,6-dione, 98% 25GR;2,2-Dimethyl-1,3-dioxane-4,6-dione cycl-Isopropylidene Malonate Malonic Acid Cyclic Isopropylidene Ester;2,2-dimethyl-1,3-dioxane-4,6-diacetone ;2,2-Dimethyl-4,6-dioxo-m-dioxane;2,2-Dimethyl-m-dioxane-4,6-dione;2,2-dimethyl-m-dioxane-6-dione
80 prices
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  • Acrotein
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  • ManufacturerAcrotein
  • Product numberAS00233
  • Product descriptionIsopropylidenemalonate 97%
  • Packaging25g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-16552
  • Product descriptionMeldrums acid 97%
  • Packaging1000g
  • Price$298
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-16552
  • Product descriptionMeldrums acid 97%
  • Packaging1000g
  • Price$298
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum's acid 95%
  • Packaging1kg
  • Price$129
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum'sacid
  • Packaging500g
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum's acid 95%
  • Packaging500g
  • Price$80
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum'sacid
  • Packaging25g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum's acid 95%
  • Packaging5g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90600
  • Product descriptionMeldrum'sacid
  • Packaging100g
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum's acid 95%
  • Packaging25g
  • Price$23
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberA037
  • Product descriptionMeldrum's acid 95%
  • Packaging100g
  • Price$35
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ90600
  • Product descriptionMeldrum'sacid
  • Packaging500g
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412608
  • Product description2,2-Dimethyl-1,3-dioxane-4,6-dione 98%
  • Packaging500g
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412608
  • Product description2,2-Dimethyl-1,3-dioxane-4,6-dione 98%
  • Packaging100g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412608
  • Product description2,2-Dimethyl-1,3-dioxane-4,6-dione 98%
  • Packaging25g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA412608
  • Product description2,2-Dimethyl-1,3-dioxane-4,6-dione 98%
  • Packaging1kg
  • Price$73
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein AS00233 Isopropylidenemalonate 97% 25g $11 2021-12-16 Buy
AHH MT-16552 Meldrums acid 97% 1000g $298 2026-05-25 Buy
AHH MT-16552 Meldrums acid 97% 1000g $298 2026-05-26 Buy
AK Scientific A037 Meldrum's acid 95% 1kg $129 2026-06-04 Buy
AK Scientific A037 Meldrum'sacid 500g $67 2021-12-16 Buy
AK Scientific A037 Meldrum's acid 95% 500g $80 2026-06-04 Buy
AK Scientific A037 Meldrum'sacid 25g $14 2021-12-16 Buy
AK Scientific A037 Meldrum's acid 95% 5g $16 2026-06-04 Buy
AK Scientific J90600 Meldrum'sacid 100g $22 2021-12-16 Buy
AK Scientific A037 Meldrum's acid 95% 25g $23 2026-06-04 Buy
AK Scientific A037 Meldrum's acid 95% 100g $35 2026-06-04 Buy
AK Scientific J90600 Meldrum'sacid 500g $49 2021-12-16 Buy
Ambeed A412608 2,2-Dimethyl-1,3-dioxane-4,6-dione 98% 500g $39 2021-12-16 Buy
Ambeed A412608 2,2-Dimethyl-1,3-dioxane-4,6-dione 98% 100g $10 2021-12-16 Buy
Ambeed A412608 2,2-Dimethyl-1,3-dioxane-4,6-dione 98% 25g $6 2021-12-16 Buy
Ambeed A412608 2,2-Dimethyl-1,3-dioxane-4,6-dione 98% 1kg $73 2021-12-16 Buy

Properties

Melting point :92-96 °C(lit.)
Boiling point :182.71°C (rough estimate)
Density :1.1311 (rough estimate)
vapor pressure :0.044-133Pa at 25℃
refractive index :1.4434 (estimate)
storage temp. :2-8°C
solubility :dioxane: soluble5%, clear to very slightly hazy, colorless to faintly yellow
pka :5.1(at 25℃)
form :Crystals or Powder
color :Brownish-white to beige-brown
Water Solubility :2.5 g/100 mL (20 ºC)
Merck :14,5817
BRN :117310
InChI :1S/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H3
InChIKey :GXHFUVWIGNLZSC-UHFFFAOYSA-N
SMILES :CC1(C)OC(=O)CC(=O)O1
LogP :-1.58-4.786 at 25℃
CAS DataBase Reference :2033-24-1(CAS DataBase Reference)
NIST Chemistry Reference :1,3-Dioxane-4,6-dione, 2,2-dimethyl-(2033-24-1)
EPA Substance Registry System :1,3-Dioxane-4,6-dione, 2,2-dimethyl- (2033-24-1)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

Isopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.

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