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ChemicalBook >> CAS DataBase List >> N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate

N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate price.
  • $11.2 - $6699
  • Product name: N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate
  • CAS: 212333-72-7
  • MF: C10H16N3OS.F6P
  • MW: 371.28
  • EINECS:805-907-2
  • MDL Number:MFCD05865266
  • Synonyms:S-(1-OXIDO-2-PYRIDYL)-N,N,N',N'-TETRAMETHYLTHIURONIUM-PF6;N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuron;S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuron;HOTT N,N,N'',N''-TETRAMETHYL-S-(1-OXIDO-2-PYRIDYL)THIURONIUM HEXAFLUOROPHOSPHATE;N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate;S-(1-Oxido-2-pyridyl)-thio-N,N,N,N-tetramethyluronium hexafluorophosphate;S-(2-Pyridyl)-N,N,Nμ,Nμ-tetramethylthiuronium N-oxide hexafluorophosphate, N,N,Nμ,Nμ-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate;2-((dimethylamino)(dimethyliminio)methylthio)pyridine 1-oxide hexafluorophosphate(V)
55 prices
Selected condition:
Brand
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth
  • Chem-Impex
  • ChemScene
  • Iris Biotech GmbH
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Thermo Scientific Chemicals
  • TRC
Package
  • 1g
  • 5g
  • 10g
  • 25G
  • 50g
  • 100g
  • 250G
  • 500G
  • ManufacturerACHEMBLOCK
  • Product numberP39782
  • Product descriptionHOTT 95%
  • Packaging25G
  • Price$125
  • Updated2026-05-27
  • Buy
  • ManufacturerAcrotein
  • Product numberNA-0415
  • Product descriptionHOTT 97%
  • Packaging25g
  • Price$199.84
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberNA-0415
  • Product descriptionHOTT 97%
  • Packaging100g
  • Price$562.83
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberNA-0415
  • Product descriptionHOTT 97%
  • Packaging100g
  • Price$562.84
  • Updated2026-05-25
  • Buy
  • ManufacturerAcrotein
  • Product numberNA-0415
  • Product descriptionHOTT 97%
  • Packaging5g
  • Price$66.91
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98%
  • Packaging100g
  • Price$589
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51444
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95%
  • Packaging100g
  • Price$440
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98%
  • Packaging25g
  • Price$167
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51444
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95%
  • Packaging25g
  • Price$125
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98%
  • Packaging5g
  • Price$49
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate]
  • Packaging5g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51444
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95%
  • Packaging1g
  • Price$12
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate]
  • Packaging1g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV1163
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98%
  • Packaging1g
  • Price$16
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51444
  • Product descriptionHOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95%
  • Packaging5g
  • Price$37
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51444
  • Product descriptionHOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate]
  • Packaging5g
  • Price$40
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK P39782 HOTT 95% 25G $125 2026-05-27 Buy
Acrotein NA-0415 HOTT 97% 25g $199.84 2026-05-25 Buy
Acrotein NA-0415 HOTT 97% 100g $562.83 2021-12-16 Buy
Acrotein NA-0415 HOTT 97% 100g $562.84 2026-05-25 Buy
Acrotein NA-0415 HOTT 97% 5g $66.91 2026-05-25 Buy
AK Scientific V1163 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98% 100g $589 2026-06-04 Buy
AK Scientific J51444 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95% 100g $440 2026-06-04 Buy
AK Scientific V1163 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98% 25g $167 2026-06-04 Buy
AK Scientific J51444 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95% 25g $125 2026-06-04 Buy
AK Scientific V1163 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98% 5g $49 2026-06-04 Buy
AK Scientific V1163 HOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate] 5g $54 2021-12-16 Buy
AK Scientific J51444 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95% 1g $12 2026-06-04 Buy
AK Scientific V1163 HOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate] 1g $14 2021-12-16 Buy
AK Scientific V1163 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 98% 1g $16 2026-06-04 Buy
AK Scientific J51444 HOTT [N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate] 95% 5g $37 2026-06-04 Buy
AK Scientific J51444 HOTT[N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuroniumhexafluorophosphate] 5g $40 2021-12-16 Buy

Properties

Melting point :120-125 °C
storage temp. :-20°C
solubility : acetonitrile, CH2Cl2, THF (moderate solubility)
form :Powder
color :White to yellow
Sensitive :Moisture Sensitive
Major Application :peptide synthesis
InChI :InChI=1S/C10H16N3OS.F6P/c1-11(2)10(12(3)4)15-9-7-5-6-8-13(9)14;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1
InChIKey :UCOGEMMJHLHOAW-UHFFFAOYSA-N
SMILES :[S+](C1=CC=CC=[N+]1[O-])=C(N(C)C)N(C)C.[P-](F)(F)(F)(F)(F)F
CAS DataBase Reference :212333-72-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuronium hexafluorophosphate is a very reactive peptide coupling reagent. It can be used as a reagent for synthesis of inhibitors for PAD1, 3, and 4. Also, it can be used for synthesis of enantiomerically pure vinylcyclopropylboronic esters, synthesis of enantiomerically pure cyclopropane building blocks, camphor-derived chiral auxiliary for hydroxyalkyl radicals, solution and solid-phase coupling, conversion of carboxylic acids to Weinreb amides and N-methoxy or N-benzoxy amides.

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