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ChemicalBook >> CAS DataBase List >> diABZI STING agonist-1 trihydrochloride

diABZI STING agonist-1 trihydrochloride

diABZI STING agonist-1 trihydrochloride price.
  • $147 - $3850
  • Product name: diABZI STING agonist-1 trihydrochloride
  • CAS: 2138299-34-8
  • MF: C42H52ClN13O7
  • MW: 886.41
  • EINECS:
  • MDL Number:MFCD31746912
  • Synonyms:diABZI STING agonist-1 trihydrochloride;STING agonist-1(compound 3)trihydrochloride;STING?agonist?diABZ;(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride);diABZI STING Agonist 3 (hydrochloride);STING agonist-1 trihydrochloride;1-[(2E)-4-[5-(Aminocarbonyl)-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-methoxy-1H-benzimidazol-1-yl]-2-buten-1-yl]-2-[[(1-ethyl-3-methyl-1H-pyrazol-5-yl)carbonyl]amino]-7-[3-(4-morpholinyl)propoxy]-1H-benzimidazole-5-carboxamide Hydrochloride (1:3);inhibit,diABZI STING agonist1 trihydrochloride,MPYS,diABZI STING agonist-1 trihydrochloride,ERIS,STING,Inhibitor,MITA,Stimulator of Interferon Genes,TMEM173,diABZI STING agonist 1 trihydrochloride
47 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mlx10mM(inDMSO)
  • 500μg
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 100MG
  • 200mg
  • Manufactureraablocks
  • Product numberAA01FNMV
  • Product description(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride)
  • Packaging2mg
  • Price$195
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FNMV
  • Product description(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride)
  • Packaging1mg
  • Price$147
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FNMV
  • Product description(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride)
  • Packaging5mg
  • Price$288
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01FNMV
  • Product description(E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride)
  • Packaging10mg
  • Price$447
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberZ238695
  • Product descriptiondiABZI STING agonist-1 trihydrochloride 95%
  • Packaging5MG
  • Price$400
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238695
  • Product descriptiondiABZI STING agonist-1 trihydrochloride 95%
  • Packaging25MG
  • Price$940
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238695
  • Product descriptiondiABZI STING agonist-1 trihydrochloride 95%
  • Packaging100MG
  • Price$1990
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number1582EN
  • Product description1-[(E)-4-[5-Carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide;trihydrochloride
  • Packaging1mg
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$858
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$903
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging25mg
  • Price$922
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging10mg
  • Price$613
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging5mg
  • Price$428
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging1mg
  • Price$204
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging50mg
  • Price$1568
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-112921B
  • Product descriptiondiABZISTINGagonist-1trihydrochloride 99.84%
  • Packaging100mg
  • Price$2803
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01FNMV (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride) 2mg $195 2026-05-30 Buy
aablocks AA01FNMV (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride) 1mg $147 2026-05-30 Buy
aablocks AA01FNMV (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride) 5mg $288 2026-05-30 Buy
aablocks AA01FNMV (E)-1-(4-(5-Carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-morpholinopropoxy)-1H-benzo[d]imidazol-1-yl)but-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzimidazole-5-carboxamide tris(hydrochloride) 10mg $447 2026-05-30 Buy
ACHEMBLOCK Z238695 diABZI STING agonist-1 trihydrochloride 95% 5MG $400 2026-05-27 Buy
ACHEMBLOCK Z238695 diABZI STING agonist-1 trihydrochloride 95% 25MG $940 2026-05-27 Buy
ACHEMBLOCK Z238695 diABZI STING agonist-1 trihydrochloride 95% 100MG $1990 2026-05-27 Buy
AK Scientific 1582EN 1-[(E)-4-[5-Carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide;trihydrochloride 1mg $430 2021-12-16 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 10mM*1mLinDMSO(Solid+Solvent) $858 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 10mM*1mLinDMSO(Solution) $903 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 25mg $922 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 10mg $613 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 5mg $428 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 1mg $204 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 50mg $1568 2026-05-26 Buy
Arctom HY-112921B diABZISTINGagonist-1trihydrochloride 99.84% 100mg $2803 2026-05-26 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: 50 mg/ml
form :A crystalline solid
color :White to yellow
InChIKey :PSJURLIZOBGEGB-HRNDJLQDSA-N
SMILES :C(N1C(=NC2=CC(C(=O)N)=CC(OCCCN3CCOCC3)=C12)NC(C1=CC(C)=NN1CC)=O)/C=C/CN1C(=NC2=CC(C(=O)N)=CC(OC)=C12)NC(C1=CC(C)=NN1CC)=O.Cl

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

diABZI STING agonist-1 is an agonist of the stimulator of interferon genes (STING) pathway. It induces secretion of IFN-β in human peripheral blood mononuclear cells (PBMCs; EC50 = 130 nM). diABZI STING agonist-1 (2.5 mg/kg) increases serum levels of IFN-β, IL-6, TNF, and KC/GROα in wild-type, but not Sting-/-, mice. It inhibits the cytopathic effect of the common cold human coronavirus 229E (HCoV-229E) in infected MRC-5 cells (EC50 = 3 nM). diABZI STING agonist-1 also decreases the level of severe acute respiratory coronavirus 2 (SARS-CoV-2) RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay. It decreases tumor volume and increases survival in a CT26 murine colorectal cancer model when administered at a dose of 3 mg/kg.

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