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ChemicalBook >> CAS DataBase List >> α,α-Difluorophenylacetic acid

α,α-Difluorophenylacetic acid

α,α-Difluorophenylacetic acid price.
  • $9 - $990
  • Product name: α,α-Difluorophenylacetic acid
  • CAS: 360-03-2
  • MF: C8H6F2O2
  • MW: 172.13
  • EINECS:623-610-4
  • MDL Number:MFCD00498146
  • Synonyms:DIFLUORO(PHENYL)ACETIC ACID;A,A-DIFLUOROPHENYLACETIC ACID;ALPHA,ALPHA-DIFLUOROPHENYLACETIC ACID;alpha-Difluoro-benzeneacetic acid;ɑ,ɑ-Difluorophenylacetic acid, 99%;2,3-DIFLUOROPHENYLACETIC ACID 95+%;2,3-DIFLUUOROPHENYL ACETIC ACID;2,3-DIFLUUOROPHENYL ACETIC
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  • ManufacturerA2B
  • Product numberAI48861
  • Product description2,2-Difluoro-2-phenylacetic acid 97%
  • Packaging1g
  • Price$9
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI48861
  • Product description2,2-Difluoro-2-phenylacetic acid 97%
  • Packaging25g
  • Price$150
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI48861
  • Product description2,2-Difluoro-2-phenylacetic acid 97%
  • Packaging100g
  • Price$528
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI48861
  • Product description2,2-Difluoro-2-phenylacetic acid 97%
  • Packaging5g
  • Price$41
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberT89857
  • Product description2,2-difluoro-2-phenylacetic acid 95%
  • Packaging100G
  • Price$990
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT89857
  • Product description2,2-difluoro-2-phenylacetic acid 95%
  • Packaging100G
  • Price$990
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT89857
  • Product description2,2-difluoro-2-phenylacetic acid 95%
  • Packaging25G
  • Price$330
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT89857
  • Product description2,2-difluoro-2-phenylacetic acid 95%
  • Packaging25G
  • Price$330
  • Updated2026-05-27
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS148555
  • Product description2,2-Difluoro-2-phenylacetic Acid?? 98%
  • Packaging1g
  • Price$29
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS148555
  • Product description2,2-Difluoro-2-phenylacetic Acid?? 98%
  • Packaging5g
  • Price$86
  • Updated2026-06-04
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS148555
  • Product description2,2-Difluoro-2-phenylacetic Acid?? 98%
  • Packaging25g
  • Price$257
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS148555
  • Product description2,2-Difluoro-2-phenylacetic Acid?? 98%
  • Packaging100g
  • Price$751
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberV5485
  • Product description2,2-Difluoro-2-phenylaceticacid
  • Packaging5g
  • Price$88
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberV5485
  • Product description2,2-Difluoro-2-phenylaceticacid
  • Packaging25g
  • Price$365
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number360032
  • Product description2,2-Difluoro-2-phenylaceticacid
  • Packaging25g
  • Price$447.86
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number360032
  • Product description2,2-Difluoro-2-phenylaceticacid
  • Packaging100g
  • Price$750.42
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A2B AI48861 2,2-Difluoro-2-phenylacetic acid 97% 1g $9 2026-05-25 Buy
A2B AI48861 2,2-Difluoro-2-phenylacetic acid 97% 25g $150 2026-05-25 Buy
A2B AI48861 2,2-Difluoro-2-phenylacetic acid 97% 100g $528 2026-05-25 Buy
A2B AI48861 2,2-Difluoro-2-phenylacetic acid 97% 5g $41 2026-05-25 Buy
ACHEMBLOCK T89857 2,2-difluoro-2-phenylacetic acid 95% 100G $990 2026-05-25 Buy
ACHEMBLOCK T89857 2,2-difluoro-2-phenylacetic acid 95% 100G $990 2026-05-27 Buy
ACHEMBLOCK T89857 2,2-difluoro-2-phenylacetic acid 95% 25G $330 2026-05-25 Buy
ACHEMBLOCK T89857 2,2-difluoro-2-phenylacetic acid 95% 25G $330 2026-05-27 Buy
Activate Scientific AS148555 2,2-Difluoro-2-phenylacetic Acid?? 98% 1g $29 2026-06-04 Buy
Activate Scientific AS148555 2,2-Difluoro-2-phenylacetic Acid?? 98% 5g $86 2026-06-04 Buy
Activate Scientific AS148555 2,2-Difluoro-2-phenylacetic Acid?? 98% 25g $257 2026-06-04 Buy
Activate Scientific AS148555 2,2-Difluoro-2-phenylacetic Acid?? 98% 100g $751 2026-06-04 Buy
AK Scientific V5485 2,2-Difluoro-2-phenylaceticacid 5g $88 2021-12-16 Buy
AK Scientific V5485 2,2-Difluoro-2-phenylaceticacid 25g $365 2021-12-16 Buy
Alichem 360032 2,2-Difluoro-2-phenylaceticacid 25g $447.86 2021-12-16 Buy
Alichem 360032 2,2-Difluoro-2-phenylaceticacid 100g $750.42 2021-12-16 Buy

Properties

Melting point :65-75 °C
Boiling point :0°C
Density :1.338±0.06 g/cm3(Predicted)
Flash point :0°C
storage temp. :Refrigerator, Under inert atmosphere
solubility :Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form :Solid
pka :1.04±0.10(Predicted)
color :White to Pale Yellow
InChI :1S/C8H6F2O2/c9-8(10,7(11)12)6-4-2-1-3-5-6/h1-5H,(H,11,12)
InChIKey :PFKSLFZFBCIJOI-UHFFFAOYSA-N
SMILES :OC(=O)C(F)(F)c1ccccc1
CAS DataBase Reference :360-03-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

α,α-Difluorophenylacetic acid is a phenylacetic acid with two fluorides on the benzylic carbon. The inductive effect of the difluoromethyl group increases the acidity of α,α-difluorophenylacetic acid. α,α-difluorophenylacetic acid and 2-arylbenzoimidazoles could be used as reaction substrates to synthesise difluoroarymethyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones through radical cascade cyclization[1].

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