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ChemicalBook >> CAS DataBase List >> Ethyl 4,4,4-trifluoroacetoacetate

Ethyl 4,4,4-trifluoroacetoacetate

Ethyl 4,4,4-trifluoroacetoacetate price.
  • $5 - $4185.12
  • Product name: Ethyl 4,4,4-trifluoroacetoacetate
  • CAS: 372-31-6
  • MF: C6H7F3O3
  • MW: 184.11
  • EINECS:206-750-7
  • MDL Number:MFCD00000424
  • Synonyms:Ethyl 4,4,4-trifluoro-3-oxobutyrate;(Trifluoroacetyl)acetic acid ethyl ester;2-(Trifluoroacetyl)acetic acid ethyl ester;3-Oxo-4,4,4-trifluorobutanoic acid ethyl ester;4,4,4-Trifluoro-3-oxobutyric acid ethyl ester;Trifluoroacetylacetic acid ethyl ester;Ethyl 4,4,4-trifluoroacetoacetate 98%;Ethyl4,4,4-trifluoroacetoacetate98%
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  • Manufactureraablocks
  • Product numberAA0035VR
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate 98%
  • Packaging25g
  • Price$7
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035VR
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate 98%
  • Packaging50g
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035VR
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate ≥98%
  • Packaging100g
  • Price$16
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035VR
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate 98%
  • Packaging250g
  • Price$29
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035VR
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate 98%
  • Packaging500g
  • Price$56
  • Updated2026-05-28
  • Buy
  • ManufacturerAHH
  • Product numberMT-12812
  • Product descriptionEthyl 4,4,4-Trifluoroacetoacetate 98%
  • Packaging1000g
  • Price$298
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-12812
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 97%
  • Packaging1000g
  • Price$298
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-12812
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 97%
  • Packaging1000g
  • Price$298
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberF661
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 98%(GC)
  • Packaging100g
  • Price$59
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93298
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 95%
  • Packaging500g
  • Price$117
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF661
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 98%(GC)
  • Packaging500g
  • Price$139
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93298
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 95%
  • Packaging1kg
  • Price$153
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF661
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 98%(GC)
  • Packaging1kg
  • Price$197
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberF661
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 98%(GC)
  • Packaging5g
  • Price$18
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ93298
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 95%
  • Packaging25g
  • Price$20
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberF661
  • Product descriptionEthyl 4,4,4-trifluoroacetoacetate 98%(GC)
  • Packaging25g
  • Price$27
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0035VR Ethyl 4,4,4-Trifluoroacetoacetate 98% 25g $7 2026-05-28 Buy
aablocks AA0035VR Ethyl 4,4,4-Trifluoroacetoacetate 98% 50g $11 2026-05-28 Buy
aablocks AA0035VR Ethyl 4,4,4-Trifluoroacetoacetate ≥98% 100g $16 2026-05-28 Buy
aablocks AA0035VR Ethyl 4,4,4-Trifluoroacetoacetate 98% 250g $29 2026-05-28 Buy
aablocks AA0035VR Ethyl 4,4,4-Trifluoroacetoacetate 98% 500g $56 2026-05-28 Buy
AHH MT-12812 Ethyl 4,4,4-Trifluoroacetoacetate 98% 1000g $298 2021-12-16 Buy
AHH MT-12812 Ethyl 4,4,4-trifluoroacetoacetate 97% 1000g $298 2026-05-25 Buy
AHH MT-12812 Ethyl 4,4,4-trifluoroacetoacetate 97% 1000g $298 2026-05-26 Buy
AK Scientific F661 Ethyl 4,4,4-trifluoroacetoacetate 98%(GC) 100g $59 2026-06-04 Buy
AK Scientific J93298 Ethyl 4,4,4-trifluoroacetoacetate 95% 500g $117 2026-06-04 Buy
AK Scientific F661 Ethyl 4,4,4-trifluoroacetoacetate 98%(GC) 500g $139 2026-06-04 Buy
AK Scientific J93298 Ethyl 4,4,4-trifluoroacetoacetate 95% 1kg $153 2026-06-04 Buy
AK Scientific F661 Ethyl 4,4,4-trifluoroacetoacetate 98%(GC) 1kg $197 2026-06-04 Buy
AK Scientific F661 Ethyl 4,4,4-trifluoroacetoacetate 98%(GC) 5g $18 2026-06-04 Buy
AK Scientific J93298 Ethyl 4,4,4-trifluoroacetoacetate 95% 25g $20 2026-06-04 Buy
AK Scientific F661 Ethyl 4,4,4-trifluoroacetoacetate 98%(GC) 25g $27 2026-06-04 Buy

Properties

Melting point :-39 °C
Boiling point :129-130 °C(lit.)
Density :1.259 g/mL at 25 °C(lit.)
vapor pressure :8hPa at 20℃
refractive index :n20/D 1.375(lit.)
Flash point :84 °F
storage temp. :Sealed in dry,Room Temperature
solubility :10g/l
form :Liquid
pka :7.76±0.10(Predicted)
Specific Gravity :1.259 (20/4℃)
color :Clear colorless to slightly yellow
PH :6.2 (10g/l, H2O, 20℃)
Water Solubility :10 g/L (20 ºC)
BRN :608353
InChI :1S/C6H7F3O3/c1-2-12-5(11)3-4(10)6(7,8)9/h2-3H2,1H3
InChIKey :OCJKUQIPRNZDTK-UHFFFAOYSA-N
SMILES :CCOC(=O)CC(=O)C(F)(F)F
CAS DataBase Reference :372-31-6(CAS DataBase Reference)
NIST Chemistry Reference :Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6)
EPA Substance Registry System :Ethyl 4,4,4-trifluoroacetoacetate (372-31-6)

Safety Information

Symbol(GHS): Flame (GHS02)Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P273 Avoid release to the environment.

Description

Ethyl trifluoroacetoacetate is used as an intermediate in synthetic chemistry. It is also used as an intermediate for agro chemicals and pharmaceuticals. Further, it is used in the preparation of fluorinated 2-thiouracil analogs as antithyroid agents.

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