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ChemicalBook >> CAS DataBase List >> 4-Aminopyridine

4-Aminopyridine

4-Aminopyridine price.
  • $7.62 - $4129.82
  • Product name: 4-Aminopyridine
  • CAS: 504-24-5
  • MF: C5H6N2
  • MW: 94.11
  • EINECS:207-987-9
  • MDL Number:MFCD00006439
  • Synonyms:4-AMINOPYRIDINE,REAGENT;AMINOPYRIDINE, 4-(P);PARA-AMINOPYRIDINE;4-AMINO PYRIDINE PYRIDIN-4-YLAMINE;Phillips 1861;phillips1861 ;Pimadin (free base);Prc 1237
66 prices
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  • Absolute Chiral
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  • ManufacturerAbsolute Chiral
  • Product numberD1326-00-N
  • Product description4-Aminopyridine 95%
  • Packaging5g
  • Price$18
  • Updated2026-05-23
  • Buy
  • ManufacturerAbsolute Chiral
  • Product numberD1326-00-N
  • Product description4-Aminopyridine 95%
  • Packaging5G
  • Price$28
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-41399
  • Product description4-Aminopyridine 97%
  • Packaging1000g
  • Price$610
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-41399
  • Product description4-Aminopyridine 97%
  • Packaging1000g
  • Price$610
  • Updated2026-05-25
  • Buy
  • ManufacturerAHH
  • Product numberMT-41399
  • Product description4-Aminopyridine 97%
  • Packaging1000g
  • Price$610
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ94087
  • Product description4-Aminopyridine
  • Packaging5g
  • Price$12
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM1555287
  • Product description4-AMINOPYRIDINE 99.00%
  • Packaging5MG
  • Price$502
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM1555287
  • Product description4-AMINOPYRIDINE 99.00%
  • Packaging100G
  • Price$2353.66
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM1555287
  • Product description4-AMINOPYRIDINE 99.00%
  • Packaging250G
  • Price$4129.82
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB3530
  • Product description4-Aminopyridine
  • Packaging10mM(in 1mL H2O)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB3530
  • Product description4-Aminopyridine
  • Packaging50g
  • Price$63
  • Updated2021-12-16
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  • ManufacturerAronis compounds
  • Product numberc08484
  • Product description4-pyridinamine
  • Packaging100mg
  • Price$80
  • Updated2021-12-16
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  • ManufacturerAtlantic Research Chemicals
  • Product numberAE00203
  • Product description4-Aminopyridine 95
  • Packaging2.5g
  • Price$12.7
  • Updated2026-05-23
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  • ManufacturerAtlantic Research Chemicals
  • Product numberAE00203
  • Product description4-Aminopyridine 95
  • Packaging250mg
  • Price$7.62
  • Updated2026-05-23
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  • ManufacturerAtlantic Research Chemicals
  • Product numberAE00203
  • Product description4-Aminopyridine 95
  • Packaging5g
  • Price$15.24
  • Updated2026-05-23
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  • ManufacturerAtlantic Research Chemicals
  • Product numberAE00203
  • Product description4-Aminopyridine 95
  • Packaging10g
  • Price$17.78
  • Updated2026-05-23
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Manufacturer Product number Product description Packaging Price Updated Buy
Absolute Chiral D1326-00-N 4-Aminopyridine 95% 5g $18 2026-05-23 Buy
Absolute Chiral D1326-00-N 4-Aminopyridine 95% 5G $28 2021-12-16 Buy
AHH MT-41399 4-Aminopyridine 97% 1000g $610 2021-12-16 Buy
AHH MT-41399 4-Aminopyridine 97% 1000g $610 2026-05-25 Buy
AHH MT-41399 4-Aminopyridine 97% 1000g $610 2026-05-26 Buy
AK Scientific J94087 4-Aminopyridine 5g $12 2021-12-16 Buy
American Custom Chemicals Corporation CHM1555287 4-AMINOPYRIDINE 99.00% 5MG $502 2021-12-16 Buy
American Custom Chemicals Corporation CHM1555287 4-AMINOPYRIDINE 99.00% 100G $2353.66 2021-12-16 Buy
American Custom Chemicals Corporation CHM1555287 4-AMINOPYRIDINE 99.00% 250G $4129.82 2021-12-16 Buy
ApexBio Technology B3530 4-Aminopyridine 10mM(in 1mL H2O) $50 2021-12-16 Buy
ApexBio Technology B3530 4-Aminopyridine 50g $63 2021-12-16 Buy
Aronis compounds c08484 4-pyridinamine 100mg $80 2021-12-16 Buy
Atlantic Research Chemicals AE00203 4-Aminopyridine 95 2.5g $12.7 2026-05-23 Buy
Atlantic Research Chemicals AE00203 4-Aminopyridine 95 250mg $7.62 2026-05-23 Buy
Atlantic Research Chemicals AE00203 4-Aminopyridine 95 5g $15.24 2026-05-23 Buy
Atlantic Research Chemicals AE00203 4-Aminopyridine 95 10g $17.78 2026-05-23 Buy

Properties

Melting point :155-158 °C (lit.)
Boiling point :273 °C (lit.)
Density :1.26
vapor pressure :0.046Pa at 25℃
refractive index :1.5560 (estimate)
Flash point :156°C
storage temp. :2-8°C
solubility :H2O: soluble50mg/mL, clear, colorless
form :Crystalline Powder, Solid or Crystals
pka :9.114(at 25℃)
color :White to faint grey to light yellow
Water Solubility :Soluble in water(112 g/L at 20°C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Merck :14,3933
BRN :105782
Henry's Law Constant :4.3×104 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Hygroscopic
Major Application :agriculture
environmental InChI :1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKey :NUKYPUAOHBNCPY-UHFFFAOYSA-N
SMILES :Nc1ccncc1
LogP :-0.76 at pH7.4
CAS DataBase Reference :504-24-5(CAS DataBase Reference)
NIST Chemistry Reference :4-Pyridinamine(504-24-5)
EPA Substance Registry System :4-Aminopyridine (504-24-5)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-Aminopyridine (4-AP) is a non-selective blocker of voltage-dependent K+-channels (Kv proteins in the KCN gene family). It has greatest potency at Kv1 (KCNA) and Kv3 (KCNC) family members (IC50s = 290, 590, 195, 13, 29, and 100 μM for subunits 1.1, 1.2, 1.3, 1.4, 3.1, and 3.2, respectively). 4-AP also blocks Kv2 and Kv4 subunits at millimolar concentrations. When administered orally, 4-AP has benefits against multiple sclerosis, while injection into the brain produces epileptiform activity and can be used to study seizures.

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