(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide
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- $16 - $3068
- Product name: (E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide
- CAS: 432531-71-0
- MF: C18H15N5O6S2
- MW: 461.47
- EINECS:
- MDL Number:
- Synonyms:(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide;Necrosulfonami;N-[4-[[(3-Methoxypyrazinyl)aMino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenaMide;(E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide;MLKL Inhibitor, Necrosulfonamide - CAS 432531-71-0 - Calbiochem;Necrosulfonamide(b);2-Propenamide, N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-;(E/Z)-Necrosulfonamide
41 prices
Selected condition:
Brand
- aablocks
- Arctom
- Biosynth
- Chemenu
- ChemScene
- CSNpharm
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 10mM*1mLinDMSO(Solution)
- 5mg
- 10mg
- 10.00mg
- 25mg
- 25.00mg
- 50mg
- 50.00mg
- 100mg
- 0.5g
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E/Z)-Necrosulfonamide 98%
- Packaging1mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E/Z)-Necrosulfonamide 98%
- Packaging5mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E/Z)-Necrosulfonamide 98%
- Packaging10mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+%
- Packaging10mg
- Price$147
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+%
- Packaging25mg
- Price$222
- Updated2021-12-16
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E/Z)-Necrosulfonamide 98%
- Packaging25mg
- Price$90
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DEZZ
- Product description(E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+%
- Packaging50mg
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging50mg
- Price$342
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging100mg
- Price$513
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging25mg
- Price$228
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging10mg
- Price$119
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging5mg
- Price$76
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging10mM*1mLinDMSO(Solution)
- Price$77
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-100573A
- Product description(E/Z)-Necrosulfonamide 98.03%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$74
- Updated2026-05-26
- Buy
- ManufacturerBiosynth
- Product numberHSA53171
- Product descriptionMLKL Inhibitor, Necrosulfonamide
- Packaging50mg
- Price$958
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DEZZ | (E/Z)-Necrosulfonamide 98% | 1mg | $16 | 2026-05-28 | Buy |
| aablocks | AA00DEZZ | (E/Z)-Necrosulfonamide 98% | 5mg | $33 | 2026-05-28 | Buy |
| aablocks | AA00DEZZ | (E/Z)-Necrosulfonamide 98% | 10mg | $54 | 2026-05-28 | Buy |
| aablocks | AA00DEZZ | (E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+% | 5mg | $104 | 2021-12-16 | Buy |
| aablocks | AA00DEZZ | (E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+% | 10mg | $147 | 2021-12-16 | Buy |
| aablocks | AA00DEZZ | (E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+% | 25mg | $222 | 2021-12-16 | Buy |
| aablocks | AA00DEZZ | (E/Z)-Necrosulfonamide 98% | 25mg | $90 | 2026-05-28 | Buy |
| aablocks | AA00DEZZ | (E)-N-[4-[N-(3-Methoxypyrazin-2-yl)sulfaMoyl]phenyl]-3-(5-nitrothiophene-2-yl)acrylaMide 98+% | 50mg | $348 | 2021-12-16 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 50mg | $342 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 100mg | $513 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 25mg | $228 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 10mg | $119 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 5mg | $76 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 10mM*1mLinDMSO(Solution) | $77 | 2026-05-26 | Buy |
| Arctom | HY-100573A | (E/Z)-Necrosulfonamide 98.03% | 10mM*1mLinDMSO(Solid+Solvent) | $74 | 2026-05-26 | Buy |
| Biosynth | HSA53171 | MLKL Inhibitor, Necrosulfonamide | 50mg | $958 | 2026-06-04 | Buy |
Properties
storage temp. :+2C to +8C
solubility :DMSO:100.0(Max Conc. mg/mL);216.7(Max Conc. mM)
form :Dark yellow solid
color :Light yellow to yellow
InChI :1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
InChIKey :FNPPHVLYVGMZMZ-XBXARRHUSA-N
SMILES :[S](=O)(=O)(Nc3ncc[n+H]c3OC)c1ccc(cc1)\N=C(/[O-])\C=C\c2[s]c(cc2)[N+](=O)[O-]
solubility :DMSO:100.0(Max Conc. mg/mL);216.7(Max Conc. mM)
form :Dark yellow solid
color :Light yellow to yellow
InChI :1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
InChIKey :FNPPHVLYVGMZMZ-XBXARRHUSA-N
SMILES :[S](=O)(=O)(Nc3ncc[n+H]c3OC)c1ccc(cc1)\N=C(/[O-])\C=C\c2[s]c(cc2)[N+](=O)[O-]
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Necrosulfonamide specifically blocks necrosis downstream of receptor-interacting serine-threonine kinase 3 (RIP3) activation. RIP3 is a key signalling molecule in the programmed necrosis (necroptosis) pathway.Related product price
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Suppliers and manufacturers
Shaanxi Dideu New Materials Co. Ltd
ATK CHEMICAL COMPANY LIMITED
Finetech Industry Limited
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
J & K SCIENTIFIC LTD.
Chemsky(shanghai)International Co.,Ltd.
Necrosulfonamide
CAS:432531-71-0




