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ChemicalBook >> CAS DataBase List >> (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide

(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide price.
  • $13 - $2707
  • Product name: (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide
  • CAS: 473727-83-2
  • MF: C21H23N3O5
  • MW: 397.42
  • EINECS:
  • MDL Number:MFCD16628072
  • Synonyms:Sch 527123;(R)-2-hydroxy-N,N-diMethyl-3-((2-((1-(5-Methylfuran-2-yl)propyl)aMino)-3,4-dioxocyclobut-1-en-1-yl)aMino)benzaMide;(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3;(R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylfuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide;3-[[3-[(Dimethylamino)carbonyl]-2-hydroxyphenyl]amino]-4-[[(R)-1-(5-methylfuran-2-yl)propyl]amino]cyclobut-3-ene-1,2-dione;SCH527123, Navarixin;Benzamide, 2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-;2-Hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3,4-dioxo-1-cyclobuten-1-yl
51 prices
Selected condition:
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  • aablocks
  • ACHEMBLOCK
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 2.5mg
  • 1mg
  • 10mM(in1mLDMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 200mg
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98%
  • Packaging1mg
  • Price$13
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98%
  • Packaging5mg
  • Price$28
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98%
  • Packaging10mg
  • Price$40
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98%
  • Packaging50mg
  • Price$112
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98%
  • Packaging25mg
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0070OQ
  • Product description(R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 95%
  • Packaging250mg
  • Price$428
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD249383
  • Product descriptionNavarixin 98%
  • Packaging250MG
  • Price$720
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberAD249383
  • Product descriptionNavarixin 98%
  • Packaging25MG
  • Price$170
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD249383
  • Product descriptionNavarixin 98%
  • Packaging100MG
  • Price$425
  • Updated2026-05-27
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001086
  • Product descriptionSCH-527123 95.00%
  • Packaging5MG
  • Price$337.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001086
  • Product descriptionSCH-527123 95.00%
  • Packaging1G
  • Price$1709.4
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3802
  • Product descriptionSCH527123
  • Packaging200mg
  • Price$1200
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3802
  • Product descriptionSCH527123
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3802
  • Product descriptionSCH 527123
  • Packaging50mg
  • Price$446
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberA3802
  • Product descriptionSCH 527123
  • Packaging200mg
  • Price$880
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3802
  • Product descriptionSCH 527123
  • Packaging10mg
  • Price$165
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98% 1mg $13 2026-05-28 Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98% 5mg $28 2026-05-28 Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98% 10mg $40 2026-05-28 Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98% 50mg $112 2026-05-28 Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 98% 25mg $68 2026-05-28 Buy
aablocks AA0070OQ (R)-2-Hydroxy-N,N-dimethyl-3-((2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)benzamide 95% 250mg $428 2026-05-28 Buy
ACHEMBLOCK AD249383 Navarixin 98% 250MG $720 2026-05-27 Buy
ACHEMBLOCK AD249383 Navarixin 98% 25MG $170 2026-05-27 Buy
ACHEMBLOCK AD249383 Navarixin 98% 100MG $425 2026-05-27 Buy
American Custom Chemicals Corporation KIN0001086 SCH-527123 95.00% 5MG $337.7 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001086 SCH-527123 95.00% 1G $1709.4 2021-12-16 Buy
ApexBio Technology A3802 SCH527123 200mg $1200 2021-12-16 Buy
ApexBio Technology A3802 SCH527123 50mg $480 2021-12-16 Buy
ApexBio Technology A3802 SCH 527123 50mg $446 2026-05-06 Buy
ApexBio Technology A3802 SCH 527123 200mg $880 2026-05-06 Buy
ApexBio Technology A3802 SCH 527123 10mg $165 2026-05-06 Buy

Properties

Melting point :118-120℃
Boiling point :548.7±60.0 °C(Predicted)
Density :1.34
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly)
pka :7.93±0.50(Predicted)
form :Solid
color :Light Yellow to Yellow
InChI :InChI=1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1
InChIKey :RXIUEIPPLAFSDF-CYBMUJFWSA-N
SMILES :C(N(C)C)(=O)C1=CC=CC(NC2C(=O)C(=O)C=2N[C@@H](C2=CC=C(C)O2)CC)=C1O

Safety Information

Symbol(GHS): Corrosion (GHS05)Health Hazard (GHS08)Exclamation Mark (GHS07)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P341 IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Sch 527123 is a potent CXCR2 antagonist. It can potentially inhibits human colon cancer liver metastasis.

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