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ChemicalBook >> CAS DataBase List >> (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid

(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid price.
  • $22 - $1800
  • Product name: (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
  • CAS: 496868-77-0
  • MF: C25H26O3
  • MW: 374.47
  • EINECS:
  • MDL Number:
  • Synonyms:Adarotene (ST1926);(E)-3-[4-[3-(1-adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid;ADAROTENE;ST 1926;ST-1926;ST1926;(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid;ST 1926;ST 1926;ST-1926;ST1926;2-Propenoic acid, 3-(4'-hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-, (2E)-;Inhibitor,inhibit,Apoptosis,ST-1926,ST 1926,Adarotene
28 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Acrotein
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 500mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99%
  • Packaging50mg
  • Price$192
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99
  • Packaging500mg
  • Price$1044
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99%
  • Packaging25mg
  • Price$121
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99%
  • Packaging10mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99%
  • Packaging5mg
  • Price$48
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00DB1V
  • Product descriptionAdarotene 99%
  • Packaging1mg
  • Price$22
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT93158
  • Product descriptionAdarotene 98%
  • Packaging100MG
  • Price$395
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberT93158
  • Product descriptionAdarotene 98%
  • Packaging25MG
  • Price$160
  • Updated2026-05-27
  • Buy
  • ManufacturerAcrotein
  • Product numberUT01079
  • Product description(E)-3-(3'-(Adamantan-1-yl)-4'-hydroxy-[1,1'-biphenyl]-4-yl)acrylicacid 97%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3419AH
  • Product descriptionAdarotene
  • Packaging1mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3419AH
  • Product descriptionAdarotene
  • Packaging25mg
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3419AH
  • Product descriptionAdarotene
  • Packaging5mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013756
  • Product descriptionADAROTENE 95.00%
  • Packaging5MG
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3143
  • Product descriptionAdarotene
  • Packaging50mg
  • Price$362
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3143
  • Product descriptionAdarotene
  • Packaging5mg
  • Price$68
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3143
  • Product descriptionAdarotene
  • Packaging10mg
  • Price$127
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00DB1V Adarotene 99% 50mg $192 2026-05-28 Buy
aablocks AA00DB1V Adarotene 99 500mg $1044 2026-05-28 Buy
aablocks AA00DB1V Adarotene 99% 25mg $121 2026-05-28 Buy
aablocks AA00DB1V Adarotene 99% 10mg $72 2026-05-28 Buy
aablocks AA00DB1V Adarotene 99% 5mg $48 2026-05-28 Buy
aablocks AA00DB1V Adarotene 99% 1mg $22 2026-05-28 Buy
ACHEMBLOCK T93158 Adarotene 98% 100MG $395 2026-05-27 Buy
ACHEMBLOCK T93158 Adarotene 98% 25MG $160 2026-05-27 Buy
Acrotein UT01079 (E)-3-(3'-(Adamantan-1-yl)-4'-hydroxy-[1,1'-biphenyl]-4-yl)acrylicacid 97% 100mg $600 2021-12-16 Buy
AK Scientific 3419AH Adarotene 1mg $99 2021-12-16 Buy
AK Scientific 3419AH Adarotene 25mg $389 2021-12-16 Buy
AK Scientific 3419AH Adarotene 5mg $147 2021-12-16 Buy
American Custom Chemicals Corporation API0013756 ADAROTENE 95.00% 5MG $220 2021-12-16 Buy
ApexBio Technology A3143 Adarotene 50mg $362 2026-05-06 Buy
ApexBio Technology A3143 Adarotene 5mg $68 2026-05-06 Buy
ApexBio Technology A3143 Adarotene 10mg $127 2026-05-06 Buy

Properties

Melting point :>240 °C
Boiling point :574.1±50.0 °C(Predicted)
Density :1.257
storage temp. :Store at -20°C
solubility :≥37.4 mg/mL in DMSO; insoluble in H2O; ≥10.97 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :-95.54±0.10(Predicted)
color :White to green
InChI :1S/C25H26O3/c26-23-7-6-21(20-4-1-16(2-5-20)3-8-24(27)28)12-22(23)25-13-17-9-18(14-25)11-19(10-17)15-25/h1-8,12,17-19,26H,9-11,13-15H2,(H,27,28)/b8-3+
InChIKey :QAWBIEIZDDIEMW-FPYGCLRLSA-N
SMILES :Oc1c(cc(cc1)c5ccc(cc5)\C=C\C(=O)O)C32CC4CC(C3)CC(C2)C4

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Adarotene has been found to have antitumor activity against different types of cancer, including acute myeloid leukemia, primary effusion lymphoma, prostate cancer and glioma. It may also be useful in treating acute lung injury through inflammation and ROS suppression via inactivating TLR4?/NF-?κB and p38?/ERK1?/2 signaling pathways.

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