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ChemicalBook >> CAS DataBase List >> 4-Chloro-2-methylthiopyrimidine

4-Chloro-2-methylthiopyrimidine

4-Chloro-2-methylthiopyrimidine price.
  • $5 - $1214.14
  • Product name: 4-Chloro-2-methylthiopyrimidine
  • CAS: 49844-90-8
  • MF: C5H5ClN2S
  • MW: 160.62
  • EINECS:256-500-6
  • MDL Number:MFCD00006083
  • Synonyms:4-Chloro-2-(methylmercapto)pyrimidine;2-methylthio-4-chloropyrimine;2-(Methylthio)-4-chloropyrimidine;4-Chloro-2-(methylthio)pyrimidine ,98%;4-Chloro-2-(Methylthio)py...;4-Chloro-2-(methylmercapto)pyrimidine, 4-Chloro-2-(methylsulphanyl)pyrimidine;4-Chloro-2-methylthiopyrimidine,97%;4-Chloro-2-methylthiopyrimidine 4-Chloro-2-(methylthio)pyrimidine
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  • Manufactureraablocks
  • Product numberAA006XU5
  • Product description4-Chloro-2-(methylthio)pyrimidine 95%
  • Packaging1g
  • Price$14
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA006XU5
  • Product description4-Chloro-2-(methylthio)pyrimidine 98%
  • Packaging5g
  • Price$20
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA006XU5
  • Product description4-Chloro-2-(methylthio)pyrimidine 98%
  • Packaging10g
  • Price$34
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA006XU5
  • Product description4-Chloro-2-(methylthio)pyrimidine 97%
  • Packaging25g
  • Price$63
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA006XU5
  • Product description4-Chloro-2-(methylthio)pyrimidine 97%
  • Packaging100g
  • Price$174
  • Updated2026-05-28
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  • ManufacturerActivate Scientific
  • Product numberAS50202
  • Product description4-Chloro-2-methylthiopyrimidine 98%
  • Packaging25g
  • Price$71
  • Updated2026-06-04
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  • ManufacturerActivate Scientific
  • Product numberAS50202
  • Product description4-Chloro-2-methylthiopyrimidine 98%
  • Packaging5g
  • Price$24
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ56763
  • Product description4-Chloro-2-methylthiopyrimidine
  • Packaging1g
  • Price$20
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberW6531
  • Product description4-Chloro-2-methylthiopyrimidine
  • Packaging5g
  • Price$80
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ56763
  • Product description4-Chloro-2-methylthiopyrimidine
  • Packaging25g
  • Price$179
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA202666
  • Product description4-Chloro-2-(methylthio)pyrimidine 98%
  • Packaging1g
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA202666
  • Product description4-Chloro-2-(methylthio)pyrimidine 98%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA202666
  • Product description4-Chloro-2-(methylthio)pyrimidine 98%
  • Packaging25g
  • Price$37
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0023301
  • Product description4-CHLORO-2-(METHYLTHIO)PYRIMIDINE 95.00%
  • Packaging10G
  • Price$1134.09
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0023301
  • Product description4-CHLORO-2-(METHYLTHIO)PYRIMIDINE 95.00%
  • Packaging25G
  • Price$1214.14
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR6414
  • Product description4-Chloro-2-(methylsulphanyl)pyrimidine 97%
  • Packaging100g
  • Price$177
  • Updated2026-06-04
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA006XU5 4-Chloro-2-(methylthio)pyrimidine 95% 1g $14 2026-05-28 Buy
aablocks AA006XU5 4-Chloro-2-(methylthio)pyrimidine 98% 5g $20 2026-05-28 Buy
aablocks AA006XU5 4-Chloro-2-(methylthio)pyrimidine 98% 10g $34 2026-05-28 Buy
aablocks AA006XU5 4-Chloro-2-(methylthio)pyrimidine 97% 25g $63 2026-05-28 Buy
aablocks AA006XU5 4-Chloro-2-(methylthio)pyrimidine 97% 100g $174 2026-05-28 Buy
Activate Scientific AS50202 4-Chloro-2-methylthiopyrimidine 98% 25g $71 2026-06-04 Buy
Activate Scientific AS50202 4-Chloro-2-methylthiopyrimidine 98% 5g $24 2026-06-04 Buy
AK Scientific J56763 4-Chloro-2-methylthiopyrimidine 1g $20 2021-12-16 Buy
AK Scientific W6531 4-Chloro-2-methylthiopyrimidine 5g $80 2021-12-16 Buy
AK Scientific J56763 4-Chloro-2-methylthiopyrimidine 25g $179 2021-12-16 Buy
Ambeed A202666 4-Chloro-2-(methylthio)pyrimidine 98% 1g $5 2021-12-16 Buy
Ambeed A202666 4-Chloro-2-(methylthio)pyrimidine 98% 5g $10 2021-12-16 Buy
Ambeed A202666 4-Chloro-2-(methylthio)pyrimidine 98% 25g $37 2021-12-16 Buy
American Custom Chemicals Corporation HCH0023301 4-CHLORO-2-(METHYLTHIO)PYRIMIDINE 95.00% 10G $1134.09 2021-12-16 Buy
American Custom Chemicals Corporation HCH0023301 4-CHLORO-2-(METHYLTHIO)PYRIMIDINE 95.00% 25G $1214.14 2021-12-16 Buy
Apolloscientific OR6414 4-Chloro-2-(methylsulphanyl)pyrimidine 97% 100g $177 2026-06-04 Buy

Properties

Melting point :−2 °C(lit.)
Boiling point :139-140 °C36 mm Hg(lit.)
Density :1.381 g/mL at 25 °C(lit.)
refractive index :n20/D 1.6(lit.)
Flash point :>230 °F
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
pka :-0.56±0.20(Predicted)
form :liquid
color :Colorless to Red to Green
Water Solubility :Not miscible or difficult to mix in water.
Sensitive :Hygroscopic
BRN :118042
InChI :InChI=1S/C5H5ClN2S/c1-9-5-7-3-2-4(6)8-5/h2-3H,1H3
InChIKey :DFOHHQRGDOQMKG-UHFFFAOYSA-N
SMILES :C1(SC)=NC=CC(Cl)=N1
CAS DataBase Reference :49844-90-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.

Description

It finds it application as a building block used in medicinal chemistry synthesis. 4-Chloro-2-methylthiopyrimidine is used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid. It is also used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors.

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