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ChemicalBook >> CAS DataBase List >> Amitriptyline hydrochloride

Amitriptyline hydrochloride

Amitriptyline hydrochloride  price.
  • $5 - $2055.9
  • Product name: Amitriptyline hydrochloride
  • CAS: 549-18-8
  • MF: C20H24ClN
  • MW: 313.86
  • EINECS:208-964-6
  • MDL Number:MFCD00012537
  • Synonyms:Amiplin;Normaln;Methanol (test Amitriptyline HCl, 1.0 mg/mL as free base);3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride;Amitriptyline hydrochloride 98+%;Amitriptyline hydrochloride solution ;3-(10,11-Dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride;Endep hydrochloride
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  • Manufactureraablocks
  • Product numberAA003NRA
  • Product descriptionAmitriptyline Hydrochloride 97%
  • Packaging1g
  • Price$18
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003NRA
  • Product descriptionAmitriptyline Hydrochloride 97%
  • Packaging5g
  • Price$23
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003NRA
  • Product descriptionAmitriptyline Hydrochloride 97%
  • Packaging25g
  • Price$63
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003NRA
  • Product descriptionAmitriptyline Hydrochloride 97%
  • Packaging100g
  • Price$157
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003NRA
  • Product descriptionAmitriptyline Hydrochloride 97%
  • Packaging500g
  • Price$540
  • Updated2026-05-28
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  • ManufacturerAK Scientific
  • Product numberH905
  • Product descriptionAmitriptyline hydrochloride 98%
  • Packaging5g
  • Price$39
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10484
  • Product descriptionAmitriptyline hydrochloride 99%(HPLC)
  • Packaging25mg
  • Price$39
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10484
  • Product descriptionAmitriptyline hydrochloride 99%(HPLC)
  • Packaging100mg
  • Price$94
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ10484
  • Product descriptionAmitriptyline hydrochloride
  • Packaging100mg
  • Price$94
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberH905
  • Product descriptionAmitriptyline hydrochloride 98%
  • Packaging1g
  • Price$18
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberH905
  • Product descriptionAmitriptyline hydrochloride 98%
  • Packaging25g
  • Price$117
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10484
  • Product descriptionAmitriptyline hydrochloride 99%(HPLC)
  • Packaging1g
  • Price$197
  • Updated2026-06-04
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  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging1g
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  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA315453
  • Product descriptionAmitriptyline hydrochloride 97+%
  • Packaging25g
  • Price$43
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003NRA Amitriptyline Hydrochloride 97% 1g $18 2026-05-28 Buy
aablocks AA003NRA Amitriptyline Hydrochloride 97% 5g $23 2026-05-28 Buy
aablocks AA003NRA Amitriptyline Hydrochloride 97% 25g $63 2026-05-28 Buy
aablocks AA003NRA Amitriptyline Hydrochloride 97% 100g $157 2026-05-28 Buy
aablocks AA003NRA Amitriptyline Hydrochloride 97% 500g $540 2026-05-28 Buy
AK Scientific H905 Amitriptyline hydrochloride 98% 5g $39 2026-06-04 Buy
AK Scientific J10484 Amitriptyline hydrochloride 99%(HPLC) 25mg $39 2026-06-04 Buy
AK Scientific J10484 Amitriptyline hydrochloride 99%(HPLC) 100mg $94 2026-06-04 Buy
AK Scientific J10484 Amitriptyline hydrochloride 100mg $94 2021-12-16 Buy
AK Scientific H905 Amitriptyline hydrochloride 98% 1g $18 2026-06-04 Buy
AK Scientific H905 Amitriptyline hydrochloride 98% 25g $117 2026-06-04 Buy
AK Scientific J10484 Amitriptyline hydrochloride 99%(HPLC) 1g $197 2026-06-04 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 100mg $5 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 1g $6 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 5g $10 2021-12-16 Buy
Ambeed A315453 Amitriptyline hydrochloride 97+% 25g $43 2021-12-16 Buy

Properties

Melting point :196-197°C
Flash point :11 °C
storage temp. :2-8°C
solubility :H2O: soluble
form :powder
pka :9.4(at 25℃)
color :white to off-white
PH :4.5~6.0 (10g/l, 25℃)
Water Solubility :almost transparency
Merck :14,487
Henry's Law Constant :1.4×102 mol/(m3Pa) at 25℃, HSDB (2015)
BCS Class :1
InChI :InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H
InChIKey :KFYRPLNVJVHZGT-UHFFFAOYSA-N
SMILES :CN(CC/C=C1/C2=C(C=CC=C2)CCC2=C/1C=CC=C2)C.[H]Cl
CAS DataBase Reference :549-18-8(CAS DataBase Reference)
EPA Substance Registry System :Amitriptyline hydrochloride (549-18-8)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Amitriptyline is a first generation tricyclic antidepressant. It strongly blocks the serotonin and norepinephrine transporters (Kds = 4.3 and 35 nM, respectively) and inhibits the serotonin 5-HT2A receptor (Ki =20 nM). Amitriptyline also antagonizes histamine H1, muscarinic acetylcholine, and α1-adrenergic receptors (Kis = 1.1, 18, and 27 nM, respectively).

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