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ChemicalBook >> CAS DataBase List >> 4-Amidinophenylmethanesulfonyl fluoride hydrochloride

4-Amidinophenylmethanesulfonyl fluoride hydrochloride

4-Amidinophenylmethanesulfonyl fluoride hydrochloride price.
  • $21 - $12166
  • Product name: 4-Amidinophenylmethanesulfonyl fluoride hydrochloride
  • CAS: 74938-88-8
  • MF: C8H10ClFN2O2S
  • MW: 252.69
  • EINECS:
  • MDL Number:MFCD00036898
  • Synonyms:APMSF HCL;APMSF HYDROCHLORIDE;4-AMIDINOPHENYLMETHANESULFONYL FLUORIDE HYDROCHLORI;P-APMSF;P-APMSF, HYDROCHLORIDE;(P-AMIDINOPHENYL)METHANESULFONYL FLUORIDE HYDROCHLORIDE;P-AMIDINOPHENYLMETHYLSULFONYLFLUORIDE, HCL;P-AMIDINOPHENYLMETHYL-SULFONYLFLUORIDE HYDROCHLORIDE
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  • aablocks
  • Activate Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Arctom
  • Biosynth
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  • Frontier Specialty Chemicals
  • Sigma-Aldrich
  • SynQuest Laboratories
Package
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  • 25mg
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  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride ≥95%
  • Packaging1mg
  • Price$37
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95%
  • Packaging5mg
  • Price$89
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95%
  • Packaging25mg
  • Price$129
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95%
  • Packaging10mg
  • Price$107
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95%
  • Packaging50mg
  • Price$155
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003KKJ
  • Product description4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95%
  • Packaging100mg
  • Price$187
  • Updated2026-05-28
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS142461
  • Product description(4-Carbamimidoylphenyl)methanesulfonyl fluoride HCl 95%
  • Packaging1g
  • Price$12166
  • Updated2026-06-04
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging50mg
  • Price$196
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging25mg
  • Price$163
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product description(4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95%
  • Packaging100mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging100mg
  • Price$236
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product description(4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95%
  • Packaging250mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging5mg
  • Price$112
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging10mg
  • Price$135
  • Updated2026-06-05
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product description(4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95%
  • Packaging50mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA639185
  • Product descriptionp-APMSF HCl 95%
  • Packaging1mg
  • Price$76
  • Updated2026-06-05
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride ≥95% 1mg $37 2026-05-28 Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95% 5mg $89 2026-05-28 Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95% 25mg $129 2026-05-28 Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95% 10mg $107 2026-05-28 Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95% 50mg $155 2026-05-28 Buy
aablocks AA003KKJ 4-Amidinophenylmethanesulfonyl fluoride hydrochloride 95% 100mg $187 2026-05-28 Buy
Activate Scientific AS142461 (4-Carbamimidoylphenyl)methanesulfonyl fluoride HCl 95% 1g $12166 2026-06-04 Buy
Ambeed A639185 p-APMSF HCl 95% 50mg $196 2026-06-05 Buy
Ambeed A639185 p-APMSF HCl 95% 25mg $163 2026-06-05 Buy
Ambeed A639185 (4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95% 100mg $175 2021-12-16 Buy
Ambeed A639185 p-APMSF HCl 95% 100mg $236 2026-06-05 Buy
Ambeed A639185 (4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95% 250mg $278 2021-12-16 Buy
Ambeed A639185 p-APMSF HCl 95% 5mg $112 2026-06-05 Buy
Ambeed A639185 p-APMSF HCl 95% 10mg $135 2026-06-05 Buy
Ambeed A639185 (4-Carbamimidoylphenyl)methanesulfonylfluoridehydrochloride 95% 50mg $144 2021-12-16 Buy
Ambeed A639185 p-APMSF HCl 95% 1mg $76 2026-06-05 Buy

Properties

Melting point :~205 °C (dec.)
storage temp. :-20°C
solubility :H2O: 50 mM Stable when aliquoted at −20°C. Half-life = 6 minutes in pH 7.0 buffer systems.
form :White solid
color :white
Water Solubility :water: 25mg/mL
BRN :9083148
InChI :1S/C8H9FN2O2S.ClH/c9-14(12,13)5-6-1-3-7(4-2-6)8(10)11;/h1-4H,5H2,(H3,10,11);1H
InChIKey :KHLLRHIUKOJXLL-UHFFFAOYSA-N
SMILES :Cl[H].NC(=N)c1ccc(CS(F)(=O)=O)cc1
CAS DataBase Reference :74938-88-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): Corrosion (GHS05)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

p-APMSF has been shown to be an irreversible and specific inhibitor of the class of plasma serine proteases which display substrate specificity for positively charged side chains of arginine and lysine amino acids. In addition, p-APMSF has been noted to be a protease inhibitor that blocks intracellular acidification, DNA fragmentation, and 5-Fluoro-2'-deoxyuridine induced cell death in mouse mammary tumor cells. This compound also demonstrates inhibitory abilities toward esterase activity in thrombin like enzymes. p-APMSF, Hydrochloride is an inhibitor of KLK11, Thrombin, Trypsin, C1r, C1s, Factor X and plasminogen.

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