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ChemicalBook >> CAS DataBase List >> 2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine price.
  • $43 - $2466
  • Product name: 2'-deoxy-2'-fluoro-2'-C-methylcytidine
  • CAS: 817204-33-4
  • MF: C10H14FN3O4
  • MW: 259.23
  • EINECS:200-001-2
  • MDL Number:MFCD13176566
  • Synonyms:(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine;PSI-6130;R 1656;PSI 6130;4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr;2'-deoxy-2'-fluoro-2'-C-methylcytidine;R 1656;ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate;4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi;4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one
70 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Synthonix
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mL(10mMinDMSO)
  • 1mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 1G
  • Manufactureraablocks
  • Product numberAA00G3MT
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99%
  • Packaging2mg
  • Price$43
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00G3MT
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99%
  • Packaging5mg
  • Price$55
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00G3MT
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99%
  • Packaging10mg
  • Price$68
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00G3MT
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99%
  • Packaging25mg
  • Price$81
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA00G3MT
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99%
  • Packaging50mg
  • Price$119
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberX203304
  • Product descriptionPSI 6130 98.00%
  • Packaging1G
  • Price$1785
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberX203304
  • Product descriptionPSI 6130 98.00%
  • Packaging1G
  • Price$1785
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX203304
  • Product descriptionPSI 6130 98.00%
  • Packaging100MG
  • Price$350
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberX203304
  • Product descriptionPSI 6130 98.00%
  • Packaging100MG
  • Price$350
  • Updated2026-05-25
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  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging50mg
  • Price$1055
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging10mg
  • Price$361
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberBA1875
  • Product descriptionPSI-6130
  • Packaging25mg
  • Price$375
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA1875
  • Product descriptionPSI-6130
  • Packaging10mg
  • Price$208
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA1875
  • Product descriptionPSI-6130
  • Packaging5mg
  • Price$143
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberBA1875
  • Product descriptionPSI-6130
  • Packaging1mL(10mMinDMSO)
  • Price$113
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00G3MT 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99% 2mg $43 2026-05-28 Buy
aablocks AA00G3MT 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99% 5mg $55 2026-05-28 Buy
aablocks AA00G3MT 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99% 10mg $68 2026-05-28 Buy
aablocks AA00G3MT 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99% 25mg $81 2026-05-28 Buy
aablocks AA00G3MT 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 99% 50mg $119 2026-05-28 Buy
ACHEMBLOCK X203304 PSI 6130 98.00% 1G $1785 2026-05-25 Buy
ACHEMBLOCK X203304 PSI 6130 98.00% 1G $1785 2026-05-27 Buy
ACHEMBLOCK X203304 PSI 6130 98.00% 100MG $350 2026-05-27 Buy
ACHEMBLOCK X203304 PSI 6130 98.00% 100MG $350 2026-05-25 Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 50mg $1055 2021-12-16 Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 5mg $228 2021-12-16 Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 10mg $361 2021-12-16 Buy
ApexBio Technology BA1875 PSI-6130 25mg $375 2026-05-06 Buy
ApexBio Technology BA1875 PSI-6130 10mg $208 2026-05-06 Buy
ApexBio Technology BA1875 PSI-6130 5mg $143 2026-05-06 Buy
ApexBio Technology BA1875 PSI-6130 1mL(10mMinDMSO) $113 2026-05-06 Buy

Properties

Melting point :216-218℃
Boiling point :482.4±55.0 °C(Predicted)
Density :1.67
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Methanol (Slightly), Water (Slightly)
pka :12.86±0.70(Predicted)
form :Solid
color :White to Light Brown
Stability :Hygroscopic
InChI :InChI=1S/C10H14FN3O4/c1-10(11)7(16)5(4-15)18-8(10)14-3-2-6(12)13-9(14)17/h2-3,5,7-8,15-16H,4H2,1H3,(H2,12,13,17)/t5-,7-,8-,10-/m1/s1
InChIKey :NYPIRLYMDJMKGW-VPCXQMTMSA-N
SMILES :OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@@](F)(C)[C@@H]1O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).

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