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ChemicalBook >> CAS DataBase List >> 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione price.
  • $4 - $275502
  • Product name: 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
  • CAS: 835616-60-9
  • MF: C13H9FN2O4
  • MW: 276.22
  • EINECS:
  • MDL Number:MFCD11840666
  • Synonyms:2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione;E3 ligase Ligand 4;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fl...;Pomalidomide Related Compound 7;TC-E3 5032;E3 ligase Ligand 4(TC-E3 5032);2-(2,6-dioxo-3-piperidinyl)-4-fluoro-1H-Isoindole-1,3(2H)-dione;135582
110 prices
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging100mg
  • Price$4
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging250mg
  • Price$5
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging1g
  • Price$7
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging5g
  • Price$21
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging10g
  • Price$32
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging25g
  • Price$64
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging50g
  • Price$118
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA008J07
  • Product description1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98%
  • Packaging100g
  • Price$218
  • Updated2026-05-28
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging10g
  • Price$125
  • Updated2026-05-21
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging100g
  • Price$440
  • Updated2026-05-21
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging5g
  • Price$76
  • Updated2026-05-21
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging1g
  • Price$50
  • Updated2026-05-21
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging200g
  • Price$993
  • Updated2026-05-21
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 95%-98%
  • Packaging1g
  • Price$1200
  • Updated2021-12-16
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  • ManufacturerAbosyn
  • Product number10-3156
  • Product description2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches)
  • Packaging400g
  • Price$1390
  • Updated2026-05-21
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  • ManufacturerACHEMBLOCK
  • Product numberM23273
  • Product description2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 97%
  • Packaging1G
  • Price$20
  • Updated2026-05-27
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Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 100mg $4 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 250mg $5 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 1g $7 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 5g $21 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 10g $32 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 25g $64 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 50g $118 2026-05-28 Buy
aablocks AA008J07 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-fluoro- 98% 100g $218 2026-05-28 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 10g $125 2026-05-21 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 100g $440 2026-05-21 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 5g $76 2026-05-21 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 1g $50 2026-05-21 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 200g $993 2026-05-21 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione 95%-98% 1g $1200 2021-12-16 Buy
Abosyn 10-3156 2-(2,6-dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione >95%(Puritymayvarybetweenbatches) 400g $1390 2026-05-21 Buy
ACHEMBLOCK M23273 2-(2,6-Dioxo-piperidin-3-yl)-4-fluoroisoindoline-1,3-dione 97% 1G $20 2026-05-27 Buy

Properties

Melting point :254-256°C
Boiling point :520.9±45.0 °C(Predicted)
Density :1.570±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Dichloromethane (Slightly, Heated), DMSO (Slightly)
pka :10.63±0.40(Predicted)
form :Solid
color :White to Off-White
InChI :InChI=1S/C13H9FN2O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5H2,(H,15,17,18)
InChIKey :CRAUTELYXAAAPW-UHFFFAOYSA-N
SMILES :C1(=O)C2=C(C(F)=CC=C2)C(=O)N1C1CCC(=O)NC1=O

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

4-Fluoro-thalidomide is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).

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