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ChemicalBook >> CAS DataBase List >> Alosetron hydrochloride

Alosetron hydrochloride

Alosetron hydrochloride price.
  • $25 - $1880
  • Product name: Alosetron hydrochloride
  • CAS: 122852-69-1
  • MF: C17H19ClN4O
  • MW: 330.81
  • EINECS:802-450-0
  • MDL Number:MFCD03453647
  • Synonyms:5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one hydrochloride;GR 68755C;2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1h-imidazol-4-yl)methyl]-1h-pyrido[4,3-b]indol-1-one hydrochloride;ALOSETRON HYDROCHLORIDE;2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride;GR 68755;GR 68755X;Alosetron hydrocloride
52 prices
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Brand
  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 10mM(in1mLDMSO)
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 500mg
  • 1g
  • 2g
  • 5g
  • 10g
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%
  • Packaging25mg
  • Price$28
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%
  • Packaging50mg
  • Price$44
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging100mg
  • Price$66
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging250mg
  • Price$72
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging1g
  • Price$185
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging5g
  • Price$805
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberZ238507
  • Product descriptionAlosetron hydrochloride 98%
  • Packaging5G
  • Price$545
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238507
  • Product descriptionAlosetron hydrochloride 98%
  • Packaging1G
  • Price$155
  • Updated2026-05-27
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1786
  • Product descriptionAlosetron Hydrochloride 98%
  • Packaging10g
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1786
  • Product descriptionAlosetron hydrochloride 97%
  • Packaging10g
  • Price$380
  • Updated2026-05-26
  • Buy
  • ManufacturerAK Scientific
  • Product numberQ640
  • Product descriptionAlosetronHCl
  • Packaging50mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94459
  • Product descriptionAlosetronHCl
  • Packaging100mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3159
  • Product descriptionAlosetron Hydrochloride
  • Packaging50mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3159
  • Product descriptionAlosetron Hydrochloride
  • Packaging50mg
  • Price$162
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3159
  • Product descriptionAlosetron Hydrochloride
  • Packaging10mM(in1mLDMSO)
  • Price$61
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3159
  • Product descriptionAlosetron Hydrochloride
  • Packaging10mg
  • Price$54
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98% 25mg $28 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98% 50mg $44 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 100mg $66 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 250mg $72 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 1g $185 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 5g $805 2026-05-25 Buy
ACHEMBLOCK Z238507 Alosetron hydrochloride 98% 5G $545 2026-05-27 Buy
ACHEMBLOCK Z238507 Alosetron hydrochloride 98% 1G $155 2026-05-27 Buy
AHH API-1786 Alosetron Hydrochloride 98% 10g $380 2021-12-16 Buy
AHH API-1786 Alosetron hydrochloride 97% 10g $380 2026-05-26 Buy
AK Scientific Q640 AlosetronHCl 50mg $135 2021-12-16 Buy
AK Scientific J94459 AlosetronHCl 100mg $144 2021-12-16 Buy
ApexBio Technology A3159 Alosetron Hydrochloride 50mg $150 2021-12-16 Buy
ApexBio Technology A3159 Alosetron Hydrochloride 50mg $162 2026-05-06 Buy
ApexBio Technology A3159 Alosetron Hydrochloride 10mM(in1mLDMSO) $61 2026-05-06 Buy
ApexBio Technology A3159 Alosetron Hydrochloride 10mg $54 2026-05-06 Buy

Properties

Melting point :288-291°C
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL at warmed
form :powder
color :white to beige
Water Solubility :H2O: ≥5mg/mL atwarmed
InChI :1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H
InChIKey :FNYQZOVOVDSGJH-UHFFFAOYSA-N
SMILES :CN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl
CAS DataBase Reference :122852-69-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lotronex (alosetron) was developed for the treatment of severe irritable bowel syndrome (IBS), and was approved for use by the US Food and Drug Administration (FDA) in 2000. Although Lotronex had a relatively high improvement rate in patients taking the drug for IBS, it was voluntarily pulled from the market by GlaxoWellcome that same year due to reports of severe adverse side effects, some resulting in death.
In 2002, Lotronex was reapproved in a supplemental New Drug Application for use under more restrictive conditions. Now with a risk management program to be consulted prior to administration of the drug, Lotronex is designated to be prescribed only when its medical benefits outweigh the risks of toxic effects; women with severe diarrhea-predominant IBS are now the focal point of prescriptions for Lotronex.

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