3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
![3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide price.](/CAS/GIF/860352-01-8.gif)
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- $14 - $7494.8
- Product name: 3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
- CAS: 860352-01-8
- MF: C17H19FN4O2S
- MW: 362.42
- EINECS:
- MDL Number:MFCD12406007
- Synonyms:3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide;5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide;AZD 7762;1-(2-((S)-piperidin-3-ylcarbamoyl)-5-(3-fluorophenyl)thiophen-3-yl)urea;5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide AZD 7762;AZD 7762 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide;(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide;AZD7762; AZD-7762
80 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 2mg
- 10mM(in 1mL DMSO)
- 25.00mg
- EvaluationSample
- 10mM*1mLinDMSO(Solid+Solvent)
- 1unit
- 100.00mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO
- 1mg
- 5mg
- 10mg
- 25mg
- 250MG
- 50mg
- 100mg
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 ≥98%
- Packaging1mg
- Price$14
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 98%
- Packaging25mg
- Price$78
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 98%
- Packaging5mg
- Price$33
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 98%
- Packaging10mg
- Price$46
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 98%
- Packaging100mg
- Price$200
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GRRV
- Product descriptionAZD7762 98%
- Packaging50mg
- Price$125
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228679
- Product descriptionAZD-7762 97.00%
- Packaging1G
- Price$1270
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228679
- Product descriptionAZD-7762 97.00%
- Packaging250MG
- Price$415
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228679
- Product descriptionAZD-7762 97.00%
- Packaging100MG
- Price$245
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5341
- Product descriptionAZD7762
- Packaging100mg
- Price$931
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging25MG
- Price$1127.86
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging5MG
- Price$730.54
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000916
- Product description(S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00%
- Packaging1G
- Price$7494.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging25mg
- Price$170
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging50mg
- Price$309
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA5919
- Product descriptionAZD7762
- Packaging100mg
- Price$517
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GRRV | AZD7762 ≥98% | 1mg | $14 | 2026-05-28 | Buy |
| aablocks | AA00GRRV | AZD7762 98% | 25mg | $78 | 2026-05-28 | Buy |
| aablocks | AA00GRRV | AZD7762 98% | 5mg | $33 | 2026-05-28 | Buy |
| aablocks | AA00GRRV | AZD7762 98% | 10mg | $46 | 2026-05-28 | Buy |
| aablocks | AA00GRRV | AZD7762 98% | 100mg | $200 | 2026-05-28 | Buy |
| aablocks | AA00GRRV | AZD7762 98% | 50mg | $125 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228679 | AZD-7762 97.00% | 1G | $1270 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228679 | AZD-7762 97.00% | 250MG | $415 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228679 | AZD-7762 97.00% | 100MG | $245 | 2026-05-27 | Buy |
| AK Scientific | SYN5341 | AZD7762 | 100mg | $931 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 25MG | $1127.86 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 5MG | $730.54 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000916 | (S)-5-(3-FLUOROPHENYL)-N-(PIPERIDIN-3-YL)-3-UREIDOTHIOPHENE-2-CARBOXAMIDE 95.00% | 1G | $7494.8 | 2021-12-16 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 25mg | $170 | 2026-05-06 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 50mg | $309 | 2026-05-06 | Buy |
| ApexBio Technology | A5919 | AZD7762 | 100mg | $517 | 2026-05-06 | Buy |
Properties
Boiling point :547.6±50.0 °C(Predicted)
Density :1.38
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :9.06±0.20(Predicted)
color :Yellow or brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Density :1.38
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :9.06±0.20(Predicted)
color :Yellow or brown
Stability :Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Actively proliferating cells experience blocks at certain checkpoints in the cell cycle when DNA damage is detected. These checkpoints allow for DNA damage repair before further cell cycle progression. Targeting signaling pathways to selectively inhibit repair at these checkpoints in tumor cells is of considerable interest to cancer therapeutics. AZD 7762 selectively inhibits the activity of checkpoint kinases (Chk) 1 and Chk2 (IC50s = 5 nM) by competitively and reversibly binding their respective ATP-binding sites (Ki = 3.6 nM for Chk1). AZD 7762 abrogates DNA damage-induced S and G2 checkpoints with an EC50 value of 10 nM and potentiates the efficacy of DNA-damage repair prohibitive agents, gemcitabine and topotecan, both in vitro and in various tumor xenografts by modulating downstream checkpoint pathway proteins.More related product prices
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3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide CAS:860352-01-8
3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide CAS:860352-01-8
