AS601245
|
- $50 - $2100
- Product name: AS601245
- CAS: 345987-15-7
- MF: C20H16N6S
- MW: 372.45
- EINECS:
- MDL Number:MFCD07772196
- Synonyms:AS601245;AS601245.TFA;JNK Inhibitor V;alpha-[2-[[2-(3-Pyridinyl)ethyl]amino]-4-pyrimidinyl]-2-benzothiazoleacetonitrile;2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile;2-Benzothiazoleacetonitrile, α-[2-[[2-(3-pyridinyl)ethyl]amino]-4-pyrimidinyl]-;CS-1619;2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
74 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 10mg
- 10mM(in 1mL DMSO)
- 5mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in1mLDMSO)
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging25mg
- Price$112
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging50mg
- Price$145
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging100mg
- Price$245
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging1mg
- Price$53
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging10mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C0UJ
- Product descriptionJNK Inhibitor V 98%
- Packaging5mg
- Price$68
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227424
- Product descriptionAS601245 97.00%
- Packaging100MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227424
- Product descriptionAS601245 97.00%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number5676CR
- Product description1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile
- Packaging25mg
- Price$810
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging50mg
- Price$631
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging10mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging25mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging5mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001543
- Product descriptionAS-601245 95.00%
- Packaging5MG
- Price$500.12
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging50mg
- Price$538
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging1mg
- Price$56
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 25mg | $112 | 2026-05-28 | Buy |
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 50mg | $145 | 2026-05-28 | Buy |
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 100mg | $245 | 2026-05-28 | Buy |
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 1mg | $53 | 2026-05-28 | Buy |
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 10mg | $87 | 2026-05-28 | Buy |
| aablocks | AA00C0UJ | JNK Inhibitor V 98% | 5mg | $68 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227424 | AS601245 97.00% | 100MG | $285 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227424 | AS601245 97.00% | 25MG | $110 | 2026-05-27 | Buy |
| AK Scientific | 5676CR | 1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile | 25mg | $810 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 50mg | $631 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 10mg | $286 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 25mg | $485 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 5mg | $169 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001543 | AS-601245 95.00% | 5MG | $500.12 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 50mg | $538 | 2026-05-06 | Buy |
| ApexBio Technology | B5942 | AS601245 | 1mg | $56 | 2026-05-06 | Buy |
Properties
Boiling point :635.6±65.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL in DMSO
pka :5.32±0.10(Predicted)
form :White to yellow solid.
color :Light yellow to yellow
InChI :1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,15H,7,10H2,(H,23,24,26)
InChIKey :RCYPVQCPYKNSTG-UHFFFAOYSA-N
SMILES :[s]1c2c(nc1C(c3nc(ncc3)NCCc4cnccc4)C#N)cccc2
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL in DMSO
pka :5.32±0.10(Predicted)
form :White to yellow solid.
color :Light yellow to yellow
InChI :1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,15H,7,10H2,(H,23,24,26)
InChIKey :RCYPVQCPYKNSTG-UHFFFAOYSA-N
SMILES :[s]1c2c(nc1C(c3nc(ncc3)NCCc4cnccc4)C#N)cccc2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
c-Jun N-terminal kinases (JNKs) phosphorylate c-Jun and regulate transcription in response to an array of inflammatory signals. JNK inhibitor V is an ATP-competitive inhibitor of JNK1, JNK2, and JNK3 (IC50s = 150, 220, and 70 nM, respectively). While initial studies demonstrated 10- to 100-fold selectivity for JNK isoforms over a panel of 25 other kinases, strong interactions of JNK inhibitor V with GSK3B, Pim-1, Pim-3, and other kinases, evaluated as a shift in thermal melting point, suggest additional targets exist. In vivo efficacy of JNK inhibitor V against JNK isoforms has been demonstrated in gerbils, mice, and rats via oral, intravenous, or intraperitoneal administration. This compound is commonly used to investigate the role of JNK signaling in cells and animals.Related product price
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Suppliers and manufacturers
career henan chemical co
![2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile](https://img.chemicalbook.com/ProductImageEN/2020-1/small/8bc99468-0952-462c-b2a2-9c76546d4ce8.jpg)
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
InvivoChem
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
$9.80
2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile CAS:345987-15-7
2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile CAS:345987-15-7
