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ChemicalBook >> CAS DataBase List >> Alosetron hydrochloride

Alosetron hydrochloride

Alosetron hydrochloride price.
  • $21 - $1880
  • Product name: Alosetron hydrochloride
  • CAS: 122852-69-1
  • MF: C17H19ClN4O
  • MW: 330.81
  • EINECS:802-450-0
  • MDL Number:MFCD03453647
  • Synonyms:5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one hydrochloride;GR 68755C;2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1h-imidazol-4-yl)methyl]-1h-pyrido[4,3-b]indol-1-one hydrochloride;ALOSETRON HYDROCHLORIDE;2,3,4,5-Tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one Hydrochloride;GR 68755;GR 68755X;Alosetron hydrocloride
73 prices
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  • aablocks
  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
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  • 10mM(in1mLDMSO)
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  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%
  • Packaging25mg
  • Price$28
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%
  • Packaging50mg
  • Price$44
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging100mg
  • Price$66
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging250mg
  • Price$72
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging1g
  • Price$185
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000JIZ
  • Product description1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC)
  • Packaging5g
  • Price$805
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberZ238507
  • Product descriptionAlosetron hydrochloride 98%
  • Packaging5G
  • Price$545
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberZ238507
  • Product descriptionAlosetron hydrochloride 98%
  • Packaging1G
  • Price$155
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberAPI-1786
  • Product descriptionAlosetron Hydrochloride 98%
  • Packaging10g
  • Price$380
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1786
  • Product descriptionAlosetron hydrochloride 97%
  • Packaging10g
  • Price$380
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberJ40177
  • Product descriptionAlosetron HCl 98%(HPLC)
  • Packaging50mg
  • Price$129
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberQ640
  • Product descriptionAlosetronHCl
  • Packaging50mg
  • Price$135
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberQ640
  • Product descriptionAlosetron HCl 98%(HPLC)
  • Packaging100mg
  • Price$199
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberQ640
  • Product descriptionAlosetron HCl 98%(HPLC)
  • Packaging25mg
  • Price$68
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ94459
  • Product descriptionAlosetronHCl
  • Packaging100mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ94459
  • Product descriptionAlosetron HCl 95%
  • Packaging100mg
  • Price$149
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98% 25mg $28 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98% 50mg $44 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 100mg $66 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 250mg $72 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 1g $185 2026-05-25 Buy
aablocks AA000JIZ 1H-Pyrido[4,3-b]indol-1-one,2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-,hydrochloride (1:1) ≥98%(HPLC) 5g $805 2026-05-25 Buy
ACHEMBLOCK Z238507 Alosetron hydrochloride 98% 5G $545 2026-05-27 Buy
ACHEMBLOCK Z238507 Alosetron hydrochloride 98% 1G $155 2026-05-27 Buy
AHH API-1786 Alosetron Hydrochloride 98% 10g $380 2021-12-16 Buy
AHH API-1786 Alosetron hydrochloride 97% 10g $380 2026-05-26 Buy
AK Scientific J40177 Alosetron HCl 98%(HPLC) 50mg $129 2026-06-04 Buy
AK Scientific Q640 AlosetronHCl 50mg $135 2021-12-16 Buy
AK Scientific Q640 Alosetron HCl 98%(HPLC) 100mg $199 2026-06-04 Buy
AK Scientific Q640 Alosetron HCl 98%(HPLC) 25mg $68 2026-06-04 Buy
AK Scientific J94459 AlosetronHCl 100mg $144 2021-12-16 Buy
AK Scientific J94459 Alosetron HCl 95% 100mg $149 2026-06-04 Buy

Properties

Melting point :288-291°C
storage temp. :2-8°C
solubility :H2O: ≥5mg/mL at warmed
form :powder
color :white to beige
Water Solubility :H2O: ≥5mg/mL atwarmed
InChI :1S/C17H18N4O.ClH/c1-11-13(19-10-18-11)9-21-8-7-15-16(17(21)22)12-5-3-4-6-14(12)20(15)2;/h3-6,10H,7-9H2,1-2H3,(H,18,19);1H
InChIKey :FNYQZOVOVDSGJH-UHFFFAOYSA-N
SMILES :CN1C2=C(C=CC=C2)C3=C1CCN(CC4=C(C)N=CN4)C3=O.Cl
CAS DataBase Reference :122852-69-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P273 Avoid release to the environment.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lotronex (alosetron) was developed for the treatment of severe irritable bowel syndrome (IBS), and was approved for use by the US Food and Drug Administration (FDA) in 2000. Although Lotronex had a relatively high improvement rate in patients taking the drug for IBS, it was voluntarily pulled from the market by GlaxoWellcome that same year due to reports of severe adverse side effects, some resulting in death.
In 2002, Lotronex was reapproved in a supplemental New Drug Application for use under more restrictive conditions. Now with a risk management program to be consulted prior to administration of the drug, Lotronex is designated to be prescribed only when its medical benefits outweigh the risks of toxic effects; women with severe diarrhea-predominant IBS are now the focal point of prescriptions for Lotronex.

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