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ChemicalBook >> CAS DataBase List >> Avacopan

Avacopan

Avacopan price.
  • $42 - $3894
  • Product name: Avacopan
  • CAS: 112093-28-4
  • MF: C25H27NO2
  • MW: 373.49
  • EINECS:
  • MDL Number:
  • Synonyms:(Z)-4-Hydroxy-N-desmethyl Tamoxifen;4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;Phenol, 4-[(1Z)-1-[4-[2-(MethylaMino)ethoxy]phenyl]-2-phenyl-1-butenyl]-;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) see D292043;(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer) ;(Z)-4-Hydroxy-N-DesMethyl TaMoxifen (Endoxifen);Endoxifen (Z-isomer);Avacopan
54 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 1mg
  • 0.5mg
  • 10
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 0.1g
  • 100MG
  • 250MG
  • 0.25g
  • 0.5g
  • 1G
  • 2g
  • Manufactureraablocks
  • Product numberAA007UN2
  • Product descriptionEndoxifen Z-isomer
  • Packaging1mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007UN2
  • Product descriptionEndoxifen Z-isomer
  • Packaging5mg
  • Price$72
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007UN2
  • Product descriptionEndoxifen Z-isomer
  • Packaging10mg
  • Price$88
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007UN2
  • Product descriptionEndoxifen Z-isomer
  • Packaging25mg
  • Price$164
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007UN2
  • Product descriptionEndoxifen Z-isomer
  • Packaging50mg
  • Price$251
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203753
  • Product descriptionEndoxifen 98%
  • Packaging100MG
  • Price$350
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203753
  • Product descriptionEndoxifen 98%
  • Packaging25MG
  • Price$200
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203753
  • Product descriptionEndoxifen 98%
  • Packaging250MG
  • Price$700
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX203753
  • Product descriptionEndoxifen 98%
  • Packaging1G
  • Price$1550
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5886
  • Product descriptionN-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers)
  • Packaging10mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010318
  • Product description(Z)-ENDOXIFEN 95.00%
  • Packaging50MG
  • Price$1437.11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010318
  • Product description(Z)-ENDOXIFEN 95.00%
  • Packaging10MG
  • Price$794.36
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging50mg
  • Price$245
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging50mg
  • Price$245
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7481
  • Product descriptionEndoxifen
  • Packaging10mg
  • Price$75
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007UN2 Endoxifen Z-isomer 1mg $44 2026-05-28 Buy
aablocks AA007UN2 Endoxifen Z-isomer 5mg $72 2026-05-28 Buy
aablocks AA007UN2 Endoxifen Z-isomer 10mg $88 2026-05-28 Buy
aablocks AA007UN2 Endoxifen Z-isomer 25mg $164 2026-05-28 Buy
aablocks AA007UN2 Endoxifen Z-isomer 50mg $251 2026-05-28 Buy
ACHEMBLOCK X203753 Endoxifen 98% 100MG $350 2026-05-27 Buy
ACHEMBLOCK X203753 Endoxifen 98% 25MG $200 2026-05-27 Buy
ACHEMBLOCK X203753 Endoxifen 98% 250MG $700 2026-05-27 Buy
ACHEMBLOCK X203753 Endoxifen 98% 1G $1550 2026-05-27 Buy
AK Scientific X5886 N-Desmethyl-4-hydroxytamoxifen,(mixtureofisomers) 10mg $280 2021-12-16 Buy
American Custom Chemicals Corporation API0010318 (Z)-ENDOXIFEN 95.00% 50MG $1437.11 2021-12-16 Buy
American Custom Chemicals Corporation API0010318 (Z)-ENDOXIFEN 95.00% 10MG $794.36 2021-12-16 Buy
ApexBio Technology B7481 Endoxifen 50mg $245 2021-12-16 Buy
ApexBio Technology B7481 Endoxifen 50mg $245 2026-05-06 Buy
ApexBio Technology B7481 Endoxifen 10mg $75 2021-12-16 Buy
ApexBio Technology B7481 Endoxifen 10mg $75 2026-05-06 Buy

Properties

Melting point :127-129°C
Boiling point :519.3±50.0 °C(Predicted)
Density :1.099±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -86°C Freezer, Under Inert Atmosphere
solubility :DMSO : 50 mg/mL (133.87 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form :Powder
pka :10.36±0.15(Predicted)
color :White to off-white
Stability :Light Sensitive, Temperature Sensitive
InChI :InChI=1S/C25H27NO2/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(27)14-10-20)21-11-15-23(16-12-21)28-18-17-26-2/h4-16,26-27H,3,17-18H2,1-2H3/b25-24-
InChIKey :MHJBZVSGOZTKRH-IZHYLOQSSA-N
SMILES :C1(O)=CC=C(/C(/C2=CC=C(OCCNC)C=C2)=C(/C2=CC=CC=C2)\CC)C=C1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger P260, P264, P270, P314, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning P273, P391, P501
Precautionary statements:
P201 Obtain special instructions before use.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.

Description

Tamoxifen (TMX; ) is a selective estrogen receptor (ER) modulator used as adjuvant therapy for estrogen-dependent breast cancer. Endoxifen is an active metabolite of TMX, produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for ERs than TMX. As the efficient conversion of TMX to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.

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