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ChemicalBook >> CAS DataBase List >> Avasimibe

Avasimibe

Avasimibe price.
  • $17 - $2250
  • Product name: Avasimibe
  • CAS: 166518-60-1
  • MF: C29H43NO4S
  • MW: 501.72
  • EINECS:1592732-453-0
  • MDL Number:MFCD00934956
  • Synonyms:Avasimibe, >=98%;2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate;[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;PD 148515;avasimibe;n-(2,6-dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide;N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE;((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER
73 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 5
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 10mM*1mLinDMSO
  • 100mg
  • 10mM*1mLinDMSO(Solution)
  • 250mg
  • 25
  • 200mg
  • 500MG
  • 1G
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 50.00g
  • 100.00g
  • 250.00g
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99%
  • Packaging1mg
  • Price$17
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99%
  • Packaging5mg
  • Price$21
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99%
  • Packaging10mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99%
  • Packaging50mg
  • Price$115
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99%
  • Packaging100mg
  • Price$205
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA001WPD
  • Product descriptionAvasimibe 99
  • Packaging200mg
  • Price$360
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10275
  • Product descriptionAvasimibe 98%
  • Packaging100MG
  • Price$235
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10275
  • Product descriptionAvasimibe 98%
  • Packaging1G
  • Price$1100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10275
  • Product descriptionAvasimibe 98%
  • Packaging5MG
  • Price$45
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10275
  • Product descriptionAvasimibe 98%
  • Packaging25MG
  • Price$75
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberV2056
  • Product descriptionavasimibe
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging50mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging100mg
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging250mg
  • Price$626
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging1g
  • Price$2128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging10mg
  • Price$191
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001WPD Avasimibe 99% 1mg $17 2026-05-28 Buy
aablocks AA001WPD Avasimibe 99% 5mg $21 2026-05-28 Buy
aablocks AA001WPD Avasimibe 99% 10mg $32 2026-05-28 Buy
aablocks AA001WPD Avasimibe 99% 50mg $115 2026-05-28 Buy
aablocks AA001WPD Avasimibe 99% 100mg $205 2026-05-28 Buy
aablocks AA001WPD Avasimibe 99 200mg $360 2026-05-28 Buy
ACHEMBLOCK 10275 Avasimibe 98% 100MG $235 2026-05-27 Buy
ACHEMBLOCK 10275 Avasimibe 98% 1G $1100 2026-05-27 Buy
ACHEMBLOCK 10275 Avasimibe 98% 5MG $45 2026-05-27 Buy
ACHEMBLOCK 10275 Avasimibe 98% 25MG $75 2026-05-27 Buy
AK Scientific V2056 avasimibe 50mg $240 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 50mg $322 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 100mg $418 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 250mg $626 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 1g $2128 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 10mg $191 2021-12-16 Buy

Properties

Melting point :178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChI :1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N
SMILES :CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Acyl-Coenzyme A:cholesterol acyltransferases (ACAT1 and ACAT2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. Avasimibe is an orally bioavailable inhibitor of ACAT (IC50s = 24 and 9.2 μM for ACAT1 and ACAT2, respectively). It reduces foam cell formation in human macrophages in vitro, enhancing free cholesterol efflux and inhibiting the uptake of modified LDL and dose-dependently reduces plasma total triglyceride and VLDL cholesterol levels in cholesterol-fed animal models. Avasimibe inhibition of ACAT has been used to decrease amyloid β generation in models of Alzheimer’s disease.

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