BTP2
|
- $25 - $1700
- Product name: BTP2
- CAS: 223499-30-7
- MF: C15H9F6N5OS
- MW: 421.32
- EINECS:
- MDL Number:MFCD00220976
- Synonyms:BTP2;N-[4-[3,5-BIS(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]PHENYL]-4-METHYL-1,2,3-THIADIAZOLE-5-CARBOXAMIDE;4-methyl-4μ-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]-1,2,3-thiadiazole-5-carboxanilide;YM-58483;CRAC Channel Inhibitor, BTP2;YM-58483(BTP2);BTP 2, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide;YM-5883
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10
- 2mg
- 5mg
- 10mg
- 50
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 100MG
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging1mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging2mg
- Price$31
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging5mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging10mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging25mg
- Price$132
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE85
- Product descriptionCRAC Channel Inhibitor, BTP2 99%
- Packaging50mg
- Price$173
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65761
- Product descriptionN-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98%
- Packaging25MG
- Price$115
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65761
- Product descriptionN-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98%
- Packaging100MG
- Price$300
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65761
- Product descriptionN-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98%
- Packaging1G
- Price$950
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number0291CA
- Product descriptionN-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
- Packaging1g
- Price$1442
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0291CA
- Product descriptionN-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
- Packaging250mg
- Price$594
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number0291CA
- Product descriptionN-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide
- Packaging100mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA172938
- Product descriptionYM-58483 98+%
- Packaging10mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA172938
- Product descriptionYM-58483 98+%
- Packaging5mg
- Price$98
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA172938
- Product descriptionYM-58483 98+%
- Packaging50mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA172938
- Product descriptionYM-58483 98+%
- Packaging25mg
- Price$167
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 1mg | $25 | 2026-05-28 | Buy |
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 2mg | $31 | 2026-05-28 | Buy |
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 5mg | $47 | 2026-05-28 | Buy |
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 10mg | $82 | 2026-05-28 | Buy |
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 25mg | $132 | 2026-05-28 | Buy |
| aablocks | AA00BE85 | CRAC Channel Inhibitor, BTP2 99% | 50mg | $173 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65761 | N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98% | 25MG | $115 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65761 | N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98% | 100MG | $300 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65761 | N-(4-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide 98% | 1G | $950 | 2026-05-27 | Buy |
| AK Scientific | 0291CA | N-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide | 1g | $1442 | 2021-12-16 | Buy |
| AK Scientific | 0291CA | N-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide | 250mg | $594 | 2021-12-16 | Buy |
| AK Scientific | 0291CA | N-[4-[3,5-Bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide | 100mg | $340 | 2021-12-16 | Buy |
| Ambeed | A172938 | YM-58483 98+% | 10mg | $128 | 2021-12-16 | Buy |
| Ambeed | A172938 | YM-58483 98+% | 5mg | $98 | 2021-12-16 | Buy |
| Ambeed | A172938 | YM-58483 98+% | 50mg | $218 | 2021-12-16 | Buy |
| Ambeed | A172938 | YM-58483 98+% | 25mg | $167 | 2021-12-16 | Buy |
Properties
Melting point :165-167 °C
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :10.53±0.70(Predicted)
form :Solid
color :white to beige
InChI :1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
InChIKey :XPRZIORDEVHURQ-UHFFFAOYSA-N
SMILES :Cc1nnsc1C(=O)Nc2ccc(cc2)-n3nc(cc3C(F)(F)F)C(F)(F)F
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :10.53±0.70(Predicted)
form :Solid
color :white to beige
InChI :1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)
InChIKey :XPRZIORDEVHURQ-UHFFFAOYSA-N
SMILES :Cc1nnsc1C(=O)Nc2ccc(cc2)-n3nc(cc3C(F)(F)F)C(F)(F)F
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Calcium release-activated calcium (CRAC) channels mediate sustained calcium influx in electrically non-excitable cells. CRAC channels are activated by the release of calcium from intracellular stores, as induced by inositol trisphosphate. CRAC channel activation is essential for the activation of leukocytes and the production of cytokines and inflammatory mediators. YM-58483 is a potent inhibitor of CRAC channels, blocking thapsigargin-induced sustained calcium influx, Th2 cytokine production, and NF-AT-driven promoter activity in T lymphocytes (IC50 = 100 nM). YM-58483 also inhibits lung interleukin-4 and cysteinyl leukotriene generation as well as airway eosinophil infiltration in animal models of asthma.More related product prices
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