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ChemicalBook >> CAS DataBase List >> CAFESTOL

CAFESTOL

CAFESTOL price.
  • $29 - $2137
  • Product name: CAFESTOL
  • CAS: 469-83-0
  • MF: C20H28O3
  • MW: 316.43
  • EINECS:
  • MDL Number:MFCD01075769
  • Synonyms:CAFESTEROL;CAFESTOL;3bα,4,5,6,7,8,9,10,10aα,10b,11,12-Dodecahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7α-methanol;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta))-;5A,8-Methano-5ah-cyclohepta(5,6)naphtho(2,1-B)furan-7-methanol, 3B,4,5,6,7,8,9,10,10A,10B,11,12-dodecahydro-7-hydroxy-10B-methyl-, (3bs,5as,7R,8R,10ar,10bs)-;Ccris 1518;CAFESTOL(SH);(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
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  • aablocks
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  • American Custom Chemicals Corporation
  • Arctom
  • Biorbyt Ltd
  • Biosynth
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  • ChemScene
  • DC Chemicals
  • Thermo Scientific Chemicals
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  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
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  • 0.1g
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  • Manufactureraablocks
  • Product numberAA003ADN
  • Product description(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98%
  • Packaging1mg
  • Price$30
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003ADN
  • Product description(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98%
  • Packaging5mg
  • Price$43
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003ADN
  • Product description(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98%
  • Packaging10mg
  • Price$73
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003ADN
  • Product description(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
  • Packaging50mg
  • Price$211
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003ADN
  • Product description(3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
  • Packaging25mg
  • Price$150
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberU106176
  • Product descriptionCafestol 98.00%
  • Packaging100MG
  • Price$440
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberU106176
  • Product descriptionCafestol 98.00%
  • Packaging50MG
  • Price$260
  • Updated2026-05-27
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  • ManufacturerAHH
  • Product numberMT-48882
  • Product descriptionCafesterol 98%
  • Packaging0.1g
  • Price$260
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberMT-48882
  • Product descriptionCafesterol 97%
  • Packaging0.1g
  • Price$260
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberMT-48882
  • Product descriptionCafesterol 97%
  • Packaging0.1g
  • Price$260
  • Updated2026-05-26
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0000605
  • Product descriptionCAFESTOL 95.00%
  • Packaging5MG
  • Price$504.64
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAB2196
  • Product descriptionCafestol 98%(HPLC)
  • Packaging20mg
  • Price$209
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-N6257
  • Product descriptionCafestol 99.20%
  • Packaging25mg
  • Price$190
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-N6257
  • Product descriptionCafestol 99.20%
  • Packaging25mg
  • Price$190
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-N6257
  • Product descriptionCafestol 99.20%
  • Packaging10mg
  • Price$100
  • Updated2026-05-25
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  • ManufacturerArctom
  • Product numberHY-N6257
  • Product descriptionCafestol 99.20%
  • Packaging10mg
  • Price$100
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003ADN (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98% 1mg $30 2026-05-28 Buy
aablocks AA003ADN (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98% 5mg $43 2026-05-28 Buy
aablocks AA003ADN (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol ≥98% 10mg $73 2026-05-28 Buy
aablocks AA003ADN (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol 50mg $211 2026-05-28 Buy
aablocks AA003ADN (3bS,5aS,7R,8R,10aR,10bS)-3b,4,5,6,7,8,9,10,10a,10b,11,12-Dodecahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol 25mg $150 2026-05-28 Buy
ACHEMBLOCK U106176 Cafestol 98.00% 100MG $440 2026-05-27 Buy
ACHEMBLOCK U106176 Cafestol 98.00% 50MG $260 2026-05-27 Buy
AHH MT-48882 Cafesterol 98% 0.1g $260 2021-12-16 Buy
AHH MT-48882 Cafesterol 97% 0.1g $260 2026-05-25 Buy
AHH MT-48882 Cafesterol 97% 0.1g $260 2026-05-26 Buy
American Custom Chemicals Corporation PXT0000605 CAFESTOL 95.00% 5MG $504.64 2021-12-16 Buy
Arctom AB2196 Cafestol 98%(HPLC) 20mg $209 2026-05-26 Buy
Arctom HY-N6257 Cafestol 99.20% 25mg $190 2026-05-25 Buy
Arctom HY-N6257 Cafestol 99.20% 25mg $190 2026-05-26 Buy
Arctom HY-N6257 Cafestol 99.20% 10mg $100 2026-05-25 Buy
Arctom HY-N6257 Cafestol 99.20% 10mg $100 2026-05-26 Buy

Properties

Melting point :160-162℃ (Decomposition) (ethyl ether pentane )
alpha :D -101°
Boiling point :468.6±45.0 °C(Predicted)
Density :1.23±0.1 g/cm3 (20 ºC 760 Torr)
RTECS :PB9185090
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Soluble in dichlormethane, DMSO or ethanol
form :White to off-white solid.
pka :14.44±0.40(Predicted)
color :Off-White to Light Beige
optical activity :-9724 (CHCl3)
Major Application :food and beverages
InChI :1S/C20H28O3/c1-18-7-5-16-14(6-9-23-16)15(18)4-8-19-10-13(2-3-17(18)19)20(22,11-19)12-21/h6,9,13,15,17,21-22H,2-5,7-8,10-12H2,1H3/t13-,15-,17+,18-,19+,20+/m1/s1
InChIKey :DNJVYWXIDISQRD-HWUKTEKMSA-N
SMILES :[o]1c2c(cc1)[C@@H]3[C@]([C@H]4[C@]5(C[C@H]([C@@](C5)(O)CO)CC4)CC3)(CC2)C
LogP :4.234 (est)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cafestol is a natural diterpene which is abundant in unfiltered coffee. It elevates serum cholesterol and triglycerides in humans, an effect which does not seem to occur in monkeys, hamsters, rats, or gerbils. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Cafestol (20 μM) also inhibits the proliferation of human umbilical vein endothelial cells and prevents their migration and tube formation on Matrigel?.

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