CYLINDROSPERMOPSIN
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- $154 - $24750
- Product name: CYLINDROSPERMOPSIN
- CAS: 143545-90-8
- MF: C15H21N5O7S
- MW: 415.42
- EINECS:
- MDL Number:MFCD01939922
- Synonyms:6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione;2,4(1h,3h)-pyrimidinedione,6-(hydroxy(2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-( ;5a-alpha,7-beta(r*))-(-)-h ;cylindrospermopsin ;sulfooxy)-1h-1,8,8b-triazaacenaphthylen-7-yl)methyl)-,(2a-alpha,3-alpha,4-alp ;PubChem ID: 42628600;2,4(1H,3H)-Pyrimidinedione, 6-[(R)-hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-
6 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 100μg
- 500μg
- 5mg
- ManufacturerCayman Chemical
- Product number10007867
- Product descriptionCylindrospermopsin ≥95%
- Packaging25μg
- Price$154
- Updated2023-06-20
- Buy
- ManufacturerCayman Chemical
- Product number10007867
- Product descriptionCylindrospermopsin ≥95%
- Packaging50μg
- Price$289
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number43408
- Product descriptionCylindrospermopsin ≥98%
- Packaging100μg
- Price$358
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number10007867
- Product descriptionCylindrospermopsin ≥95%
- Packaging100μg
- Price$405
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10007867
- Product descriptionCylindrospermopsin ≥95%
- Packaging500μg
- Price$1937
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC991455
- Product descriptionCylindrospermopsin
- Packaging5mg
- Price$24750
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10007867 | Cylindrospermopsin ≥95% | 25μg | $154 | 2023-06-20 | Buy |
| Cayman Chemical | 10007867 | Cylindrospermopsin ≥95% | 50μg | $289 | 2024-03-01 | Buy |
| Cayman Chemical | 43408 | Cylindrospermopsin ≥98% | 100μg | $358 | 2026-04-30 | Buy |
| Cayman Chemical | 10007867 | Cylindrospermopsin ≥95% | 100μg | $405 | 2024-03-01 | Buy |
| Cayman Chemical | 10007867 | Cylindrospermopsin ≥95% | 500μg | $1937 | 2021-12-16 | Buy |
| TRC | C991455 | Cylindrospermopsin | 5mg | $24750 | 2021-12-16 | Buy |
Properties
Density :1.3937 (rough estimate)
refractive index :1.6460 (estimate)
storage temp. :−20°C
solubility :DMSO: soluble
form :white powder
pka :-3.78±0.18(Predicted)
EPA Substance Registry System :Cylindrospermopsin (143545-90-8)
refractive index :1.6460 (estimate)
storage temp. :−20°C
solubility :DMSO: soluble
form :white powder
pka :-3.78±0.18(Predicted)
EPA Substance Registry System :Cylindrospermopsin (143545-90-8)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Cylindrospermopsin is a cyanotoxin alkaloid natural product isolated from Cylindrospermopsis raciborskii blooms. Cylindrospermopsin is an inhibitor of protein synthesis, shown to block the in vitro activity of uridine monophosphate synthase complex. The acute toxicity of Cylindrospermopsin is described to be mediated by CYP (cytochrome p450)-generated metabolites, as inhibitors of CYP (cytochrome p450) completely blocked Cylindrospermopsin toxicity. Decreased activity in reduced glutathione (GSH) synthesis correlated with Cylindrospermopsin exposure may further support the damage caused by metabolites through diminished cellular scavenging of reactive oxygen species. Blockade of CYP (cytochrome p450) by inhibitors also protected cells from Cylindrospermopsin-mediated decreases in GSH levels, indicating that CYP (cytochrome p450)-generated metabolites may also mediate the reduction of GSH synthesis and fall in cellular levels of GSH.Related product price
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