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ChemicalBook >> CAS DataBase List >> Capsaicin

Capsaicin

Capsaicin price.
  • $28 - $2214.42
  • Product name: Capsaicin
  • CAS: 404-86-4
  • MF: C18H27NO3
  • MW: 305.41
  • EINECS:206-969-8
  • MDL Number:MFCD00017259
  • Synonyms:(e)-6-nonenamid ;capsaicin standard;Capsaicin,8-Methyl-N-vanillyl-trans-6-nonenamide;capsaicin(fromoleoresinofcapsicum)plusrelatedcapsaicinoids ;n-(4-hydroxy-3-methoxybenzyl-8-methylnon-trans-6-enamide ;nci-c56564 ;trans-n-((4-hydroxy-3-methoxyphenyl)methyl)-8-methyl-6-nonenamide ;(E)-8-Methyl-N-(4-hydroxy-3-methoxybenzyl)-6-nonenamide
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  • aablocks
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  • Manufactureraablocks
  • Product numberAA0034I3
  • Product description(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95%
  • Packaging1g
  • Price$35
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0034I3
  • Product description(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95%
  • Packaging5g
  • Price$90
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0034I3
  • Product description(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95%
  • Packaging25g
  • Price$268
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0034I3
  • Product description(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95%
  • Packaging100g
  • Price$763
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberV143039
  • Product descriptionCapsaicin 98%
  • Packaging25G
  • Price$460
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberV143039
  • Product descriptionCapsaicin 98%
  • Packaging5G
  • Price$155
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0157-M250
  • Product descriptionCapsaicin ≥95%(HPLC)
  • Packaging250mg
  • Price$212
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0941-M050
  • Product descriptionCapsaicin from Capsicum annuum ≥95%
  • Packaging50mg
  • Price$59
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0941-M250
  • Product descriptionCapsaicin from Capsicum annuum ≥95%
  • Packaging250mg
  • Price$236
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-C0941-G001
  • Product descriptionCapsaicin from Capsicum annuum ≥95%
  • Packaging1g
  • Price$500
  • Updated2026-05-06
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  • ManufacturerAK Scientific
  • Product numberN735
  • Product descriptionCapsaicin,fromnaturalsource
  • Packaging100mg
  • Price$28
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHBL0009474
  • Product descriptionCAPSAICIN 95.00%
  • Packaging5MG
  • Price$532
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHBL0009474
  • Product descriptionCAPSAICIN 95.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHBL0009474
  • Product descriptionCAPSAICIN 95.00%
  • Packaging100MG
  • Price$1963.5
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberC6366
  • Product descriptionCapsaicin
  • Packaging50mg
  • Price$74
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberC6366
  • Product descriptionCapsaicin
  • Packaging200mg
  • Price$183
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0034I3 (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95% 1g $35 2026-05-28 Buy
aablocks AA0034I3 (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95% 5g $90 2026-05-28 Buy
aablocks AA0034I3 (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95% 25g $268 2026-05-28 Buy
aablocks AA0034I3 (E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide 95% 100g $763 2026-05-28 Buy
ACHEMBLOCK V143039 Capsaicin 98% 25G $460 2026-05-27 Buy
ACHEMBLOCK V143039 Capsaicin 98% 5G $155 2026-05-27 Buy
Adipogen Life Sciences CDX-C0157-M250 Capsaicin ≥95%(HPLC) 250mg $212 2021-12-16 Buy
Adipogen Life Sciences CDX-C0941-M050 Capsaicin from Capsicum annuum ≥95% 50mg $59 2026-05-06 Buy
Adipogen Life Sciences CDX-C0941-M250 Capsaicin from Capsicum annuum ≥95% 250mg $236 2026-05-06 Buy
Adipogen Life Sciences CDX-C0941-G001 Capsaicin from Capsicum annuum ≥95% 1g $500 2026-05-06 Buy
AK Scientific N735 Capsaicin,fromnaturalsource 100mg $28 2021-12-16 Buy
American Custom Chemicals Corporation HBL0009474 CAPSAICIN 95.00% 5MG $532 2021-12-16 Buy
American Custom Chemicals Corporation HBL0009474 CAPSAICIN 95.00% 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation HBL0009474 CAPSAICIN 95.00% 100MG $1963.5 2021-12-16 Buy
ApexBio Technology C6366 Capsaicin 50mg $74 2026-05-06 Buy
ApexBio Technology C6366 Capsaicin 200mg $183 2026-05-06 Buy

Properties

Melting point :62-65 °C(lit.)
Boiling point :210-220 C
Density :1.1037 (rough estimate)
refractive index :1.5100 (estimate)
FEMA :3404 | CAPSAICIN
Flash point :113 °C
storage temp. :2-8°C
solubility :H2O: insoluble
form :Off-white solid
pka :9.76±0.20(Predicted)
color :Off-white
Odor :mild warm herbal
Odor Type :herbal
biological source :Capsicum sp.
Water Solubility :insoluble
Merck :14,1768
BRN :2816484
Henry's Law Constant :9.9×107 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Stable. Incompatible with strong oxidizing agents.
Major Application :metabolomics
vitamins, nutraceuticals, and natural products Cosmetics Ingredients Functions :SKIN CONDITIONING
FRAGRANCE Cosmetic Ingredient Review (CIR) :Capsaicin (404-86-4)
InChI :1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
InChIKey :YKPUWZUDDOIDPM-SOFGYWHQSA-N
SMILES :COc1cc(CNC(=O)CCCC\C=C\C(C)C)ccc1O
LogP :4.00
CAS DataBase Reference :404-86-4(CAS DataBase Reference)
EPA Substance Registry System :Capsaicin (404-86-4)

Safety Information

Symbol(GHS): Corrosion (GHS05)Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Capsaicin is the primary active component of the heat and pain-eliciting lipid-soluble fraction of the Capsicum pepper. Capsaicin is present in natural hot pepper extracts along with a number of impurities, including dihydrocapsaicin and several lesser impurities. Separation by HPLC is required in order to obtain capsaicin of consistently high purity and reproducible quality. VR1 is a heat-activated calcium ion channel which functions as part of the normal nociceptive pain pathway. Capsaicin elicits a sensation of burning pain by activation of VR1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. Chronic application of capsaicin leads to desensitization of these pain fibers and has been widely exploited in various non-prescription pain remedies.

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