Diosmetin
|
- $5 - $770
- Product name: Diosmetin
- CAS: 520-34-3
- MF: C16H12O6
- MW: 300.26
- EINECS:208-291-8
- MDL Number:MFCD00017425
- Synonyms:3',5,7-TRIHYDROXY-4'METHOXYFLAVONE;4'-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;4-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;5,7,3'-TRIHYDROXY-4'-METHOXYFLAVONE;DIOSMETIN;5,7-Dihydroxy-2-[3-hydroxy-4-methoxyphenyl]-[4H]-1-benzopyran-4-one;4'-Methylluteolin;Diosmetol
102 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 50mg
- 100MG
- 200mg
- 250mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mlx10mM(inDMSO)
- 5mg
- 10mg
- 20mg
- 25mg
- 500mg
- 1g
- 1000mg
- 2g
- 5g
- 10.00g
- 25.00g
- 50g
- 100.00g
- 10mM(in1mLDMSO)
- 10g
- 25g
- 100g
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 98%
- Packaging250mg
- Price$7
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 98%
- Packaging1g
- Price$9
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96%
- Packaging5g
- Price$23
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96%
- Packaging10g
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96%
- Packaging25g
- Price$72
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003PLZ
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 97%
- Packaging100g
- Price$274
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX191764
- Product description5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one 95.00%
- Packaging100G
- Price$280
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberAPI-1501
- Product descriptionDiosmetin 98%
- Packaging25g
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1501
- Product descriptionDiosmetin 97%
- Packaging25g
- Price$750
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ51310
- Product descriptionDiosmetin
- Packaging1g
- Price$117
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging25g
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging10g
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA124051
- Product descriptionDiosmetin 96%
- Packaging5g
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0005231
- Product descriptionDIOSMETIN 95.00%
- Packaging100MG
- Price$202.65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5990
- Product descriptionDiosmetin
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5990
- Product descriptionDiosmetin
- Packaging50mg
- Price$53
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 98% | 250mg | $7 | 2026-05-28 | Buy |
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 98% | 1g | $9 | 2026-05-28 | Buy |
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96% | 5g | $23 | 2026-05-28 | Buy |
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96% | 10g | $37 | 2026-05-28 | Buy |
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 96% | 25g | $72 | 2026-05-28 | Buy |
| aablocks | AA003PLZ | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl);-4H-chromen-4-one 97% | 100g | $274 | 2026-05-28 | Buy |
| ACHEMBLOCK | X191764 | 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one 95.00% | 100G | $280 | 2026-05-27 | Buy |
| AHH | API-1501 | Diosmetin 98% | 25g | $750 | 2021-12-16 | Buy |
| AHH | API-1501 | Diosmetin 97% | 25g | $750 | 2026-05-26 | Buy |
| AK Scientific | J51310 | Diosmetin | 1g | $117 | 2021-12-16 | Buy |
| Ambeed | A124051 | Diosmetin 96% | 25g | $104 | 2021-12-16 | Buy |
| Ambeed | A124051 | Diosmetin 96% | 10g | $53 | 2021-12-16 | Buy |
| Ambeed | A124051 | Diosmetin 96% | 5g | $32 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PXT0005231 | DIOSMETIN 95.00% | 100MG | $202.65 | 2021-12-16 | Buy |
| ApexBio Technology | B5990 | Diosmetin | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B5990 | Diosmetin | 50mg | $53 | 2026-05-06 | Buy |
Properties
Melting point :256-258°C
Boiling point :576.7±50.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
pka :6.50±0.40(Predicted)
form :Solid
color :light yellow to yellow
Water Solubility :19μg/L at 20℃
BRN :294492
Henry's Law Constant :3.3×1012 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Hygroscopic
Major Application :metabolomics
vitamins, nutraceuticals, and natural products Cosmetics Ingredients Functions :SKIN CONDITIONING
InChI :1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
InChIKey :MBNGWHIJMBWFHU-UHFFFAOYSA-N
SMILES :COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
LogP :3.1 at 20℃
CAS DataBase Reference :520-34-3(CAS DataBase Reference)
Boiling point :576.7±50.0 °C(Predicted)
Density :1.512±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in acetonitrile, DMSO (60 mg/ml), and ethanol (17 mg/ml), clear, light yellow to yellow.
pka :6.50±0.40(Predicted)
form :Solid
color :light yellow to yellow
Water Solubility :19μg/L at 20℃
BRN :294492
Henry's Law Constant :3.3×1012 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Hygroscopic
Major Application :metabolomics
vitamins, nutraceuticals, and natural products Cosmetics Ingredients Functions :SKIN CONDITIONING
InChI :1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
InChIKey :MBNGWHIJMBWFHU-UHFFFAOYSA-N
SMILES :COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
LogP :3.1 at 20℃
CAS DataBase Reference :520-34-3(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Diosmetin is a natural O-methylated flavone that is structurally related to luteolin . It reversibly inhibits cytochrome P450 (CYP) isoforms 1A1 and 1B1 in human liver microsomes with Ki values of 89 and 16 nM, respectively. It less potently inhibits CYP2C8 and CYP2C9 (Kis = 3.1 and 1.7 μM, respectively). While diosmetin inhibits CYP1A1 activity, it increases the transcription of the CYP1A1 gene in MCF-7 cells by activating the aryl hydrocarbon receptor when applied at 5 μM. Diosmetin also inhibits signaling through the stem cell factor receptor, c-Kit, at micromolar concentrations.Related product price
-
Luteolin
$5-1595 -
Coumarin 6
$10-807 -
Coumarin-3-carboxylic acid
$5-1068.61
Suppliers and manufacturers
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Diosmetin
CAS:520-34-3
BINBO BIOLOGICAL CO.,LTD
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Zheyan Biotech Co., Ltd.
Diosmetin
CAS:520-34-3
