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ChemicalBook >> CAS DataBase List >> Debio-1347

Debio-1347

Debio-1347 price.
  • $15 - $1700
  • Product name: Debio-1347
  • CAS: 1265229-25-1
  • MF: C20H16N6O
  • MW: 356.38
  • EINECS:
  • MDL Number:MFCD28502053
  • Synonyms:Debio-1347;FF284;CH5183284 (Debio-1347);(5-amino-1-(2-methyl-3H-benzo[d]imidazol-5-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone;CH5183284;Debio-1347:CH5183284;CH5183284;CH-5183284;CH 5183284;CS-1637
61 prices
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 1g
  • 10mM(in 1mL DMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10.00mg
  • 25.00mg
  • 50.00mg
  • 10mM*1mLinDMSO
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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  • 100MG
  • 250MG
  • 10mM(in1mLDMSO)
  • Manufactureraablocks
  • Product numberAA009CJH
  • Product descriptionCH5183284 (Debio-1347) 99%(HPLC)
  • Packaging1mg
  • Price$15
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CJH
  • Product descriptionCH5183284 (Debio-1347) 99%(HPLC)
  • Packaging5mg
  • Price$29
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CJH
  • Product descriptionCH5183284 (Debio-1347) 99%(HPLC)
  • Packaging10mg
  • Price$42
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CJH
  • Product descriptionCH5183284 (Debio-1347) 99%(HPLC)
  • Packaging50mg
  • Price$109
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA009CJH
  • Product descriptionCH5183284 (Debio-1347) 99%(HPLC)
  • Packaging25mg
  • Price$69
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberQ65616
  • Product description(5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98%
  • Packaging250MG
  • Price$880
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberQ65616
  • Product description(5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98%
  • Packaging250MG
  • Price$880
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65616
  • Product description(5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98%
  • Packaging100MG
  • Price$440
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberQ65616
  • Product description(5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98%
  • Packaging100MG
  • Price$440
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product number2863DS
  • Product descriptionDebio-1347
  • Packaging25mg
  • Price$626
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284(Debio-1347)
  • Packaging25mg
  • Price$334
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284(Debio-1347)
  • Packaging100mg
  • Price$698
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284 (Debio-1347)
  • Packaging10mM(in1mLDMSO)
  • Price$66
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284 (Debio-1347)
  • Packaging25mg
  • Price$187
  • Updated2026-05-06
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  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284 (Debio-1347)
  • Packaging5mg
  • Price$55
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4985
  • Product descriptionCH5183284(Debio-1347)
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CJH CH5183284 (Debio-1347) 99%(HPLC) 1mg $15 2026-05-28 Buy
aablocks AA009CJH CH5183284 (Debio-1347) 99%(HPLC) 5mg $29 2026-05-28 Buy
aablocks AA009CJH CH5183284 (Debio-1347) 99%(HPLC) 10mg $42 2026-05-28 Buy
aablocks AA009CJH CH5183284 (Debio-1347) 99%(HPLC) 50mg $109 2026-05-28 Buy
aablocks AA009CJH CH5183284 (Debio-1347) 99%(HPLC) 25mg $69 2026-05-28 Buy
ACHEMBLOCK Q65616 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98% 250MG $880 2026-05-25 Buy
ACHEMBLOCK Q65616 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98% 250MG $880 2026-05-27 Buy
ACHEMBLOCK Q65616 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98% 100MG $440 2026-05-25 Buy
ACHEMBLOCK Q65616 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone 98% 100MG $440 2026-05-27 Buy
AK Scientific 2863DS Debio-1347 25mg $626 2021-12-16 Buy
ApexBio Technology B4985 CH5183284(Debio-1347) 25mg $334 2021-12-16 Buy
ApexBio Technology B4985 CH5183284(Debio-1347) 100mg $698 2021-12-16 Buy
ApexBio Technology B4985 CH5183284 (Debio-1347) 10mM(in1mLDMSO) $66 2026-05-06 Buy
ApexBio Technology B4985 CH5183284 (Debio-1347) 25mg $187 2026-05-06 Buy
ApexBio Technology B4985 CH5183284 (Debio-1347) 5mg $55 2026-05-06 Buy
ApexBio Technology B4985 CH5183284(Debio-1347) 5mg $103 2021-12-16 Buy

Properties

Boiling point :775.5±55.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥35.6 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :solid
pka :10.51±0.10(Predicted)
color :Off-white to yellow
CAS DataBase Reference :1265229-25-1

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CH5183284 is a potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC50s = 9.3, 7.6, and 22 nM, respectively). It less potently inhibits FGFR4 and platelet-derived growth factor receptor β (IC50s = 290 and 560 nM, respectively) and displays IC50 values greater than 1 μM for a diverse panel of tyrosine and serine/threonine kinases. CH5183284 is effective against FGFR2 containing the gatekeeper mutation V564F. Moreover, it inhibits the growth of cancer cells expressing FGFR genetic alterations both in vitro and in xenograft mouse models.

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