Dofetilide
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- $5 - $2835.25
- Product name: Dofetilide
- CAS: 115256-11-6
- MF: C19H27N3O5S2
- MW: 441.56
- EINECS:638-817-5
- MDL Number:MFCD00869707
- Synonyms:Tikosyn;beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide;Methanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl) phenyl);Tikosym;Methyl[2-[4-(methylsulfonylamino)phenoxy]ethyl][4-(methylsulfonylamino)phenethyl]amine;N-[4-[2-[N-Methyl-2-(4-methylsulfonylaminophenoxy)ethylamino]ethyl]phenyl]methanesulfonamide;U-68798;N-[4-[2-[2-[4-(methanesulfonamido)phenyl]ethyl-methylamino]ethoxy]phenyl]methanesulfonamide
81 prices
Selected condition：
Brand
- aablocks
- AHH
- AK Scientific
- Ambeed
- ApexBio Technology
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 25
- 10mg
- 5mg
- 10mM*1mLinDMSO
- 5
- 25mg
- 50mg
- 100.00mg
- 0.1g
- 100mg
- 200mg
- 250mg
- 250.00mg
- 500mg
- 1.00g
- 10mM(in1mLDMSO)
- 1g
- 10mM(in 1mL DMSO)
- 2g
- 5g
- 10g
- 25g
- 250 mg
- Manufactureraablocks
- Product numberAA000GGG
- Product descriptionN-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%
- Packaging10mg
- Price$5
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GGG
- Product descriptionN-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%
- Packaging50mg
- Price$12
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GGG
- Product descriptionN-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%
- Packaging100mg
- Price$21
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GGG
- Product descriptionN-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%
- Packaging250mg
- Price$51
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000GGG
- Product descriptionN-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%(HPLC)
- Packaging1g
- Price$164
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberAPI-1606
- Product descriptionDofetilide 98%
- Packaging0.1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1606
- Product descriptionDofetilide 97%
- Packaging0.1g
- Price$370
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberI881
- Product descriptionDofetilide 98%(HPLC)
- Packaging250mg
- Price$59
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI881
- Product descriptionDofetilide 98%(HPLC)
- Packaging100mg
- Price$36
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI881
- Product descriptionDofetilide
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberI881
- Product descriptionDofetilide 98%(HPLC)
- Packaging25mg
- Price$16
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI881
- Product descriptionDofetilide 98%(HPLC)
- Packaging1g
- Price$147
- Updated2026-06-04
- Buy
- ManufacturerAmbeed
- Product numberA253881
- Product descriptionN-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+%
- Packaging50mg
- Price$23
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253881
- Product descriptionN-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+%
- Packaging100mg
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253881
- Product descriptionN-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+%
- Packaging25mg
- Price$16
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA253881
- Product descriptionN-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+%
- Packaging5mg
- Price$7
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000GGG | N-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98% | 10mg | $5 | 2026-05-25 | Buy |
| aablocks | AA000GGG | N-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98% | 50mg | $12 | 2026-05-25 | Buy |
| aablocks | AA000GGG | N-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98% | 100mg | $21 | 2026-05-25 | Buy |
| aablocks | AA000GGG | N-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98% | 250mg | $51 | 2026-05-25 | Buy |
| aablocks | AA000GGG | N-[4-(2-{2-[4-(methanesulphonamido)phenoxyl]-N-methylethylamino}ethyl)phenyl]-methanesulphonamide 98%(HPLC) | 1g | $164 | 2026-05-25 | Buy |
| AHH | API-1606 | Dofetilide 98% | 0.1g | $370 | 2021-12-16 | Buy |
| AHH | API-1606 | Dofetilide 97% | 0.1g | $370 | 2026-05-26 | Buy |
| AK Scientific | I881 | Dofetilide 98%(HPLC) | 250mg | $59 | 2026-06-04 | Buy |
| AK Scientific | I881 | Dofetilide 98%(HPLC) | 100mg | $36 | 2026-06-04 | Buy |
| AK Scientific | I881 | Dofetilide | 5mg | $39 | 2021-12-16 | Buy |
| AK Scientific | I881 | Dofetilide 98%(HPLC) | 25mg | $16 | 2026-06-04 | Buy |
| AK Scientific | I881 | Dofetilide 98%(HPLC) | 1g | $147 | 2026-06-04 | Buy |
| Ambeed | A253881 | N-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+% | 50mg | $23 | 2021-12-16 | Buy |
| Ambeed | A253881 | N-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+% | 100mg | $34 | 2021-12-16 | Buy |
| Ambeed | A253881 | N-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+% | 25mg | $16 | 2021-12-16 | Buy |
| Ambeed | A253881 | N-(4-(2-(Methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide 98+% | 5mg | $7 | 2021-12-16 | Buy |
Properties
Melting point :147-1490C
Boiling point :614.1±65.0 °C(Predicted)
Density :1.344±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :7.0, 9.0, 9.6(at 25℃)
form :powder
color :white to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
InChIKey :IXTMWRCNAAVVAI-UHFFFAOYSA-N
SMILES :CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc2ccc(NS(C)(=O)=O)cc2
CAS DataBase Reference :115256-11-6(CAS DataBase Reference)
Boiling point :614.1±65.0 °C(Predicted)
Density :1.344±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
pka :7.0, 9.0, 9.6(at 25℃)
form :powder
color :white to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
InChIKey :IXTMWRCNAAVVAI-UHFFFAOYSA-N
SMILES :CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc2ccc(NS(C)(=O)=O)cc2
CAS DataBase Reference :115256-11-6(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Dofetilide is a class III antiarrhythmic agent that prolongs cardiac action potential duration by selectively inhibiting the rapidly activating inward rectifying component of net delayed rectifier K+ current (IC50 = 31.5 nM in guinea pig cardiomyocytes). However, at 1 μM dofetilide demonstrates pro-arrhythmic activity, inducing early after depolarizations (prolonged repolarization) in cell models and Torsade de Pointes in animal models. Given this adverse side effect, dofetilide has been cautiously used in the treatment of atrial fibrillation, the conversion of flutter to sinus rhythm, and in the maintenance of sinus rhythm after conversion.Related product price
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Suppliers and manufacturers
Shaanxi Haibo Biotechnology Co., Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Zhejiang ZETian Fine Chemicals Co. LTD
Dofetilide
CAS:115256-11-6
